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- Pretreatment with antiserum against dynorphin, substance P, or cholecystokinin enhances the morphine-produced anti-allodynia in the sciatic nerve ligated mice.
- Terminating migraine with allodynia and ongoing central sensitization using parenteral administration of COX1/COX2 inhibitors.
- Almotriptan in migraine patients who respond poorly to oral sumatriptan: a double-blind, randomized trial.
- CRF2 receptor activation prevents colorectal distension induced visceral pain and spinal ERK1/2 phosphorylation in rats.
- Involvement of vagal opioid receptors in respiratory effects of morphine in anaesthetized rats.
- Effect of licofelone against mechanical hyperalgesia and cold allodynia in the rat model of incisional pain.
- The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation.
- Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
- Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB2 receptor.
- SAR and biological evaluation of novel trans-3,4-dimethyl-4-arylpiperidine derivatives as opioid antagonists.
- Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain.
- Epinephrine-induced excitation and sensitization of rat C-fiber nociceptors.
- Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities.
- Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats.
- Herpes simplex virus type 1 latency-associated transcript expression protects trigeminal ganglion neurons from apoptosis.
- A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia.
- Influence of the dopamine D2 receptor knockout on pain-related behavior in the mouse.
- Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain.
- Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical allodynia of CCI rats.
- Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing.
- [Nalpha-benzylTyr1,cyclo(D-Asp5,Dap8)]- dynorphin A-(1-11)NH2 cyclized in the "address" domain is a novel kappa-opioid receptor antagonist.
- Adamantyl cannabinoids: a novel class of cannabinergic ligands.
- ATP is a mediator of chemosensory transduction in the central nervous system.
- Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents.
- Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.
- 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles.
- Differential behavioral tolerance to the delta-opioid agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley rats.
- The P2X3 antagonist P1, P5-di[inosine-5'] pentaphosphate binds to the desensitized state of the receptor in rat dorsal root ganglion neurons.
- Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats.
- Formulation, characterization, and evaluation of ketorolac tromethamine-loaded biodegradable microspheres.
- Anticonvulsant drugs for acute and chronic pain.
- Gabapentin for acute and chronic pain.
- Antidepressants for neuropathic pain.
- Endogenous opioid mechanisms partially mediate P2X3/P2X2/3-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain.
- Design, synthesis, and preliminary evaluation of gabapentin-pregabalin mutual prodrugs in relieving neuropathic pain.
- Ryanodine receptors are involved in muscarinic antinociception in mice.
- Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties.
- Novel endomorphin-2 analogs with mu-opioid receptor antagonist activity.
- Intrarectal lidocaine is an effective treatment for abdominal pain associated with diarrhea-predominant irritable bowel syndrome.
- Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice.
- Activation and activators of TRPV1 and their pharmaceutical implication.
- Focus on the three key enzymes hydrolysing endocannabinoids as new drug targets.
- Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
- Efficacy of the 5-HT1A agonist, buspirone hydrochloride, in migraineurs with anxiety: a randomized, prospective, parallel group, double-blind, placebo-controlled study.
- Anti-allodynic interactions between NMDA receptor channel blockers and morphine or clonidine in neuropathic rats.
- A prostacyclin receptor antagonist inhibits the sensitized release of substance P from rat sensory neurons.
- TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury.
- A multicenter, double-blind, safety study of QR-333 for the treatment of symptomatic diabetic peripheral neuropathy. A preliminary report.
- Involvement of GABA and opioid peptide receptors in sevoflurane-induced antinociception in rat spinal cord.
- Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus.