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- Assessment of single-dose benzodiazepines on insulin secretion, insulin sensitivity and glucose effectiveness in healthy volunteers: a double-blind, placebo-controlled, randomized cross-over trial [ISRCTN08745124].
- Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.
- Insulin resistance and endothelial dysfunction in type 2 diabetes patients with or without microalbuminuria.
- Is diabetes an independent risk factor for mortality after myocardial infarction? The ARIC (Atherosclerosis Risk in Communities) Surveillance Study.
- 4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.
- Randomized trial of effect of alendronate continuation versus discontinuation in women with low BMD: results from the Fracture Intervention Trial long-term extension.
- Risk-benefit profile for raloxifene: 4-year data From the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial.
- Muscle-specific overexpression of CD36 reverses the insulin resistance and diabetes of MKR mice.
- A central role for inflammation in the pathogenesis of diabetic retinopathy.
- Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes.
- Impact of diabetes mellitus on long-term outcome after unstable angina and non-ST-segment elevation myocardial infarction treated with a very early invasive strategy.
- Risk factor management in diabetic and non-diabetic patients with coronary heart disease. Findings from the EUROASPIRE I AND II surveys.
- Enhancement of early- and late-phase insulin secretion and insulin sensitivity by the combination of repaglinide and metformin in type 2 diabetes mellitus.
- Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products.
- Rosiglitazone improves, while Glibenclamide worsens blood pressure control in treated hypertensive diabetic and dyslipidemic subjects via modulation of insulin resistance and sympathetic activity.
- Synthesis of tetrahydronaphthyl thioureas as potent appetite suppressants.
- Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid.
- Effect of oral CCK-1 agonist GI181771X on fasting and postprandial gastric functions in healthy volunteers.
- Efficacy of pharmacotherapy for weight loss in adults with type 2 diabetes mellitus: a meta-analysis.
- Impact of diabetes and previous myocardial infarction on long-term survival: 25-year mortality follow-up of primary screenees of the Multiple Risk Factor Intervention Trial.
- Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines.
- Physical training may enhance beta-cell function in type 2 diabetes.
- Body size and breast cancer risk: findings from the European Prospective Investigation into Cancer And Nutrition (EPIC).
- Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility.
- Transgenic rescue of insulin receptor-deficient mice.
- Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin.
- Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study.
- In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.
- Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX(2)R) antagonists.
- Rational design of potent and selective NH-linked aryl/heteroaryl cathepsin K inhibitors.
- Alpha,alpha-difluoro-beta-ketophosphonates as potent inhibitors of protein tyrosine phosphatase 1B.
- Elevation of intracavernous pressure and NO-cGMP activity by a new herbal formula in penile tissues of aged and diabetic rats.
- Atorvastatin improves diabetic dyslipidemia and increases lipoprotein lipase activity in vivo.
- Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study.
- Visceral fat in hypertension: influence on insulin resistance and beta-cell function.
- Novel 18beta-glycyrrhetinic acid analogues as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenases.
- Taurine increases glucose sensitivity of UCP2-overexpressing beta-cells by ameliorating mitochondrial metabolism.
- Tetrahydrobiopterin increases insulin sensitivity in patients with type 2 diabetes and coronary heart disease.
- Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.
- A virtual screening approach to finding novel and potent antagonists at the melanin-concentrating hormone 1 receptor.
- Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists.
- Expression of ICAM-1 by osteoblasts in healthy individuals and in patients suffering from osteoarthritis and osteoporosis.
- Acute and chronic effects of FR-149175, a beta 3-adrenergic receptor agonist, on energy expenditure in Zucker fatty rats.
- Effect of a beta-3 agonist on food intake in two strains of rats that differ in susceptibility to obesity.
- Flt3-ligand treatment prevents diabetes in NOD mice.
- Are we underestimating diabetes-related lower-extremity amputation rates? Results and benefits of the first prospective study.
- Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes.
- The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes.
- Expression levels of genes likely involved in glucose-sensing in the obese Zucker rat brain.
- NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy.
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