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- Effect of methylthiouracil on the colloidopexic capacity of hepatosplenic macrophages through thyroid function depression.
- Clinical safety and tolerability of montelukast, a leukotriene receptor antagonist, in controlled clinical trials in patients aged > or = 6 years.
- Synthesis of small molecule CDC25 phosphatases inhibitors.
- Synthesis of analogs of (1,4)-3- and 5-imino oxazepane, thiazepane, and diazepane as inhibitors of nitric oxide synthases.
- Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma.
- Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.
- Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial.
- Arterial neovascularization and inflammation in vulnerable patients: early and late signs of symptomatic atherosclerosis.
- Novel antiinflammatory vascular benefits of systemic and stent-based delivery of ethylisopropylamiloride.
- A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction.
- A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats.
- BAY 50-4798, a novel, high-affinity receptor-specific recombinant interleukin-2 analog, induces dose-dependent increases in CD25 expression and proliferation among unstimulated, human peripheral blood mononuclear cells in vitro.
- Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats.
- Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices.
- Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains.
- Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia/reperfusion.
- Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis.
- Cloning and sequencing of variable region cDNAs of a novel human monoclonal antibody to carcinoembryonic antigen, and generation of a single chain variable fragmented antibody.
- Serendipitous discovery of an unexpected rearrangement leads to two new classes of potential protease inhibitors.
- The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes.
- Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase.
- Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: implications in cancer immunotherapy.
- Dual effect of angiotensin-converting enzyme inhibition on angiogenesis in type 1 diabetic mice.
- Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial.
- Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis.
- Characterization of (2R, 3S)-2-([[4-(2-butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzyme.
- Infliximab treatment for steroid-refractory acute graft-versus-host disease.
- Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.
- Donepezil improved memory in multiple sclerosis in a randomized clinical trial.
- Anti-tumor effect of an intratumoral administration of dendritic cells in combination with TS-1, an oral fluoropyrimidine anti-cancer drug, and OK-432, a streptococcal immunopotentiator: involvement of toll-like receptor 4.
- The metabolic syndrome, inflammation, and risk of cognitive decline.
- A new class of acyclic 2-alkyl-1,1,2-triaryl (Z)-olefins as selective cyclooxygenase-2 inhibitors.
- HMG-CoA reductase inhibitor attenuates experimental autoimmune myocarditis through inhibition of T cell activation.
- Ligand discovery using small molecule microarrays.
- Anti-interleukin-12 antibody for active Crohn's disease.
- Tumor necrosis factor-alpha (TNF-alpha) promotes cell survival during spermatogenesis, and this effect can be blocked by infliximab, a TNF-alpha antagonist.
- Zafirlukast treatment for acute asthma: evaluation in a randomized, double-blind, multicenter trial.
- Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity.
- Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies.
- Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis.
- Characterization of a population of small macrophages in induced sputum of patients with chronic obstructive pulmonary disease and healthy volunteers.
- Pharmacokinetics, safety, and tolerability of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist after oral administration at single and multiple once-daily ascending doses in healthy volunteers.
- 3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.
- Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors.
- Atorvastatin reduces arterial stiffness in patients with rheumatoid arthritis.
- Pathophysiological role of human beta-defensins 2 in gastric mucosa.
- Antibody-mediated transduction of p53 selectively kills cancer cells.
- Theobromine inhibits sensory nerve activation and cough.
- BRAK/CXCL14 is a potent inhibitor of angiogenesis and a chemotactic factor for immature dendritic cells.
- Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label study.
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