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• 1. Molecular docking of four beta-amyloid1-42 fragments on the alpha7 nicotinic receptor: delineating the binding site of the Abeta peptides.
• 2. Stable expression and characterisation of a human alpha 7 nicotinic subunit chimera: a tool for functional high-throughput screening.
• 3. Galantamine modulates nicotinic receptor and blocks Abeta-enhanced glutamate toxicity.
• 4. Effects of Abeta1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the tau-protein and on the alpha7 nicotinic acetylcholine receptor in vitro.
• 5. Discovery of the alpha7 nicotinic acetylcholine receptor agonists. (R)-3'-(5-Chlorothiophen-2-yl)spiro-1-azabicyclo[2.2.2]octane-3,5'-[1',3']oxazolidin-2'-one as a novel, potent, selective, and orally bioavailable ligand.
• 6. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation.
• 7. A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.
• 8. Reversal of isolation-rearing-induced PPI deficits by an alpha7 nicotinic receptor agonist.
• 9. Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.
• 10. alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats.
• 11. Anti-inflammatory properties of cholinergic up-regulation: A new role for acetylcholinesterase inhibitors.
• 12. Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice.
• 13. 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs.
• 14. Microglial alpha7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role.
• 15. Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.
• 16. Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia.
• 17. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.
• 18. SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia.
• 19. Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists.
• 20. Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
• 21. alpha7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation.
• 22. The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents.
• 23. Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.
• 24. Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells.
• 25. METABOLISM AND DISPOSITION OF A SELECTIVE {alpha}7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST IN HUMANS.
• 26. Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators.
• 27. The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease.
• 28. Discovery, Synthesis, and Structure Activity of a Highly Selective alpha7 Nicotinic Acetylcholine Receptor Antagonist.
• 29. Novel alpha7 nicotinic receptor isoforms and deficient cholinergic transcription in schizophrenia.
• 30. Distinct profiles of {alpha}7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes.
• 31. Phencyclidine-Induced Cognitive Deficits in Mice Are Improved by Subsequent Subchronic Administration of the Novel Selective alpha7 Nicotinic Receptor Agonist SSR180711.
• 32. Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys.
• 33. Pharmacological Characteristics and Binding Modes of Caracurine V Analogues and Related Compounds at the Neuronal alpha7 Nicotinic Acetylcholine Receptor.
• 34. Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors.
• 35. Screening for new agonists against Alzheimer's disease.
• 36. [3H]A-585539, A NOVEL HIGH AFFINITY {alpha}7 NEURONAL NICOTINIC RECEPTOR AGONIST: RADIOLIGAND BINDING CHARACTERIZATION TO RAT AND HUMAN BRAIN.
• 37. Improvement of contextual memory by S 24795 in aged mice: comparison with memantine.
• 38. {alpha}7 Nicotinic Receptor Up-regulation in Cholinergic Basal Forebrain Neurons in Alzheimer Disease.
• 39. alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues.
• 40. Comparative effects of the alpha7 nicotinic partial agonist, S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice.
• 41. alpha-RgIA, a Novel Conotoxin That Blocks the alpha9alpha10 nAChR: Structure and Identification of Key Receptor-Binding Residues.
• 42. Cardiovascular effects of activation of central alpha7 and alpha4beta2 nAChRs: a role for vasopressin in anaesthetized rats.
• 43. First administration of cytidine diphosphocholine and galantamine in schizophrenia: a sustained alpha7 nicotinic agonist strategy.
• 44. Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar beta amyloid peptide (1-42)-stimulated microglia.
• 45. Allosteric modulation of alpha7 nicotinic receptors selectively depolarizes hippocampal interneurons, enhancing spontaneous GABAergic transmission.
• 46. Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer.
• 47. Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: In vitro and in vivo activity.
• 48. The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat.
• 49. Lack of beneficial galantamine effect for smoking behavior: A double-blind randomized trial in people with schizophrenia.
• 50. Stimulation of the alpha4beta2 nicotinic receptor by 5-I A-85380 improves auditory gating in DBA/2 mice.

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