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Vaccines: The World Market

What are the trends that are fueling a new boom in vaccine production and sales? Why is an industry so commonly associated with children finding an increasing marketplace among adult populations? What makes this class of drugs likely to grow at a faster rate than other pharmaceutical products? These are among the questions answered in Kalorama’s in-depth report, Vaccines: The World Market.

With the historic success of vaccines in virtually eliminating diseases such as small pox and polio, and with their obvious benefit of preventing disease before it occurs, vaccines are a 9 billion dollar industry and new vaccines continue to be developed. Kalorama’s Vaccines: The World Market breaks down the market for pediatric and adult vaccines, providing background information, revenue numbers, and a discussion of critical trends that anyone seeking opportunities in vaccines will need to be aware of. Among the exhaustive information in this report, the following topics are discussed in detail:

 

• Current and Forecasted Revenue Figures to 2012 for strategic planning and new product consideration.
• Over 55 Tables and Figures for easy access to decision support information in proposals, internal memos and business plans.
• Round-up of Key Vaccine Companies for benchmarking and marketplace knowledge.
• Discussion of Major Issues and Trends such as vaccine safety and legislation affecting the market; current vaccine companies can use to plan, new entrants can use to quickly bring themselves up to speed on the marketplace and steer clear of problem areas.
• Review of the Robust Vaccine Pipeline (nearly 200+ drugs in development) and how they are expected to affect the market, so that executives can adjust business decisions to the most likely market scenario. Current revenues and revenue forecasts to 2012 are included for the following pediatric vaccine categories:
• DTaP & DTP Vaccines
• Hep Vaccines
• HiB Vaccines
• MMR Vaccines
• Combination Vaccines
• Pneumococcal Vaccines
• Polio Vaccines
• Varicella Vaccines
• Other Pediatric Vaccines

As well as Revenues and Forecasts to 2012 for the following adult vaccine categories:

Influenza Vaccines

Hepatitis Vaccines

Pneumococcal Vaccines

Travel, DT and other Adult Vaccines

 

Additionally, this report provides current market size and forecasts the following cancer vaccines:

• Breast Cancer
• Cervical Cancer
• Colon/Rectal Cancer
• Lung
• Melanoma
• Prostate
• Other cancers.

Kalorama’s trusted information-gathering process provides the most accurate study of the market for vaccines available today. Information and analysis presented in this report is based on extensive interviews with senior management of top companies. While financial reports, major research literature and government information is culled, information is corroborated and key market insights originate from interviews with industry leaders.

Sales, Marketing, Business Development and Strategic Planning executives in the pharmaceutical industry, advertising agencies and consulting groups who work with pharmaceutical clients as well as institutional librarians are among those who will benefit from Kalorama’s detailed analysis of the vaccine market.

As part of its detailed coverage, Kalorama’s Vaccines: The World Market features profiles of the following companies:

• Acambis plc
• AlphaVax, Inc.
• Avant Immunotherapeutics
• Bavarian Nordic A/S
• Baxter Healthcare
• Berna Biotech AG
• Emergent Biosolutions
• GlaxoSmithKline
• MEDIMMUNE
• Merck & Co. Inc
• Nabi Biopharmaceuticals
• Novartis
• PFIZER
• Pharmexa
• SANOFI Pasteur
• Vical
• Wyeth

 

Table of Contents

Chapter One: Executive Summary

• Scope And Methodology
• Overview
• Pediatric Preventative Vaccines
  • The Market
• Adult Preventative Vaccines
  • The Market
• Total Preventative Market
• Emerging Cancer Vaccines
  • The Market
• Issues and Trends

Chapter Two: Introduction to Vaccines

• A Brief History: The Development of Vaccines
• The Immune Response
• Mechanism of Action
• Types of Vaccines
  • Attenuated (Weakened) Live Viruses
  • Killed (Inactivated) Viruses
  • Toxoid Vaccines
  • Genetically Engineered/Modified Vaccines
• Vaccine Approval Process

Chapter Three: Pediatric Preventive Vaccines

• Introduction
• Childhood Immunization in the United States
  • Childhood Immunization Rates
  • Challenges to the Vaccine Delivery System
  • Recommended Childhood Immunization Schedule
• Pediatric Vaccine Products
  • BCG Vaccines
  • Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio Vaccines
  • Haemophilus Influenzae Type B Vaccines
  • Hepatitis A Vaccines
  • Measles, Mumps and Rubella Vaccines
  • Pneumococcal Conjugate Vaccine
  • Rotavirus Vaccines
  • Varicella Vaccines
• Cost of Vaccines in the United States
• Pediatric Vaccines in Development
  • Global Initiatives for Vaccine Research
  • Diarrhea-Related Diseases
  • Acute Respiratory Infections
  • Other Conditions
• The World Market for Pediatric Preventive Vaccines
  • Total Market Size and Forecast
  • DTP and DTaP Vaccine Market
  • Hepatitis Vaccine Market
  • Haemophilus Influenzae Type B Vaccine Market
  • Measles, Mumps and Rubella Vaccines
  • Combination Vaccines Market
  • Pneumococcal Vaccine
  • Poliovirus Vaccine
  • Varicella Vaccines
  • Other Vaccines Market

Chapter Four: Adult Preventive Vaccines

• Introduction
• Adult Vaccine-Preventable Diseases: Facts and Figures
• Global Virological Surveillance Program
• Recommendations for Adult Immunizations
  • Vaccine Recommendations for International Travel
  • CDC’s Recommendations for Yellow Fever Vaccination
  • WHO International Health Regulations
• Adult Vaccine Products
  • BCG Vaccines
  • Cholera Vaccines
  • Diphtheria-Tetanus Vaccines
  • Hepatitis Vaccines
  • Influenza Vaccines
  • Japanese Encephalitis Vaccine
  • Pneumococcal Disease Vaccines
  • Rabies Vaccine
  • Typhoid Vaccines
  • Yellow Fever Vaccines
• Adult Vaccines in Development
• Global Initiatives for Vaccine Research
  • Cholera
  • Dengue Fever
  • Epstein-Barr Virus
  • HIV/AIDS
  • Helicobacter Pylori
  • Hepatitis
  • Herpesvirus
  • Leishmaniasis
  • Malaria
  • Severe Acute Respiratory Syndrome
  • Shigella
  • West Nile Virus
• The World Market for Adult Preventive Vaccines
  • Total Market Size and Forecast
  • Hepatitis Market
  • Influenza Vaccine Market
  • Travel, DT, and Miscellaneous Vaccine Market

Chapter Five: Preventive Vaccines Market Summary

• Trends Driving the Preventive Vaccines Market
• Market Size and Forecast
  • Vaccine Market Competitors
  • Pediatric Vaccines
  • Adult Vaccines

Chapter Six: Emerging Cancer Vaccines

• History and Growth of the Cancer Treatment Market
• Cancer Vaccine Technology
  • Antigen/Adjuvant Vaccines
  • Whole Cell Tumor Vaccines
  • Dendritic Cell (DC) Vaccines
  • Viral Vectors and DNA Vaccines
  • Idiotype Vaccines
  • Types of Therapeutic Vaccines
• Cancer Statistics
• Available Cancer Vaccines
  • Bladder Cancer
  • Cervical Cancer
  • Colorectal Cancer
  • Melanoma
• Types of Cancers Susceptible to Vaccines
  • Breast Cancer
  • Gastrointestinal Cancer
  • Kidney
  • Leukemia
  • Lung Cancer
  • Lymphoma
  • Multiple Myeloma
  • Neuroblastoma
  • Ovarian Cancer
  • Prostate Cancer
  • Sarcoma
• Cancer Vaccine Pipeline
  • Colorectal Cancer
  • Lung Cancer
  • GV-1001
  • Lymphoma
  • Melanoma
  • Prostate Cancer
  • Other Cancers
  • Telomerase
• The Emerging Cancer Vaccine Market
  • Total Market Size and Forecast
  • Competitor Analysis

Chapter Seven: Issues and Trends

• Vaccine Safety
  • Pre-licensure Evaluation
  • Post-Licensure Surveillance
  • The Vaccine Injury Compensation Program
  • World Health Organization
  • Other Initiatives
  • The Future of Vaccine Safety
• Vaccine Shortages
  • Preventing Future Shortages in the U.S.
  • Addressing Shortages in Developing Nations
• Preventing Pandemics
• Vaccines and Bioterrorism
  • Overview
  • Project Bioshield Act of 2004
  • National Bio and Agro-Defense Facility
  • Anthrax
  • Smallpox
  • Plague
  • Botulism
  • Tularemia
  • Viral Hemorrhagic Fevers
• Innovations in Vaccine Delivery Systems
  • Edible Vaccines
  • Mucosal Delivery
  • Intranasal Delivery
  • Oral Vaccines
  • Vaccine Patches

chapter eight: Company Profiles

• Acambis plc
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• AlphaVax, Inc.
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
• Avant Immunotherapeutics
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Bavarian Nordic A/S
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Baxter Healthcare
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Berna Biotech AG
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Emergent biosolutions
  • History and Lines of Business
  • Strategic Acquisition and Alliance
  • Vaccine Products
  • Financial
• GlaxoSmithKline
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Medimmune
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Merck & Co. Inc
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Nabi Biopharmaceuticals
  • History and Lines of Business
  • Strategic Alliance
  • Vaccine Products
  • Financial Information
• Novartis
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Pfizer
  • History and Lines of Business
  • Vaccine products
  • Financial Information
• Pharmexa
  • History and Lines of Business
  • Vaccine Products
  • Financial Information
• Sanofi Pasteur
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Vical
  • History and Lines of Business
  • Strategic Alliances
  • Technology Platform
  • Therapeutic Cancer Vaccine Products in Clinical Trials
  • Financial Information
• Wyeth
  • History and Lines of Business
  • Vaccine Products
  • Financial Information

Appendix: Company Directory

 

LIST OF EXHIBITS

 

Chapter One: Executive Summary

• Figure 1-1: World Market Pediatric Vaccines by Current andEmerging Markets 2003-2012
• Figure 1-2: World Market Adult Vaccines by Current andEmerging Markets 2003-2012
• Figure 1-3: World Market Cancer Vaccines by Current andEmerging Markets 2003-2012

Chapter Two: Introduction to Vaccines

• Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2005
• Table 2-2: Vaccine-Preventable Diseases

Chapter Three: Pediatric Preventive Vaccines

• Table 3-1: Global Immunization Rates by Vaccine Type 2005
• Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 1999-2005
• Table 3-3: U.S. Recommended Childhood Immunization Schedule, 2006
• Table 3-4: Cost of Vaccines: Private Sector Versus Public Sector Prices Last Reviewed/Updated, September 2006 (Vaccine, Brand Name, Packaging, CDC Cost/Dose, Private Sector Cost/Dose, Contract End Date, Manufacturer)
• Table 3-5: Selected Pediatric Vaccines in Development (Company, Product Name, Indication, Development Status)
• Table 3-6: World Market for Pediatric Vaccines by Type (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)
• Figure 3-1: Market Share of Pediatric Vaccines by Type 2005
• Figure 3-2: Market Share of Pediatric Vaccines, by Type 2012
• Table 3-7: World DTP and DTaP Vaccine Market 2003-2012
• Table 3-8: World Pediatric Hepatitis Vaccine Market 2003-2012
• Table 3-9: World Hib Vaccine Market, 2003-2012
• Table 3-10: World MMR Vaccines Market 2003-2012
• Table 3-11: World Combination Vaccines Market 2003-2012
• Table 3-12: World Pediatric Pneumococcal Vaccine Market 2003-2012
• Table 3-13: World Poliovirus Vaccine Market 2003-2012
• Table 3-14: World Varicella Vaccine Market 2003-2012
• Table 3-15: Other Vaccines Market 2003-2012

Chapter Four: Adult Preventive Vaccines

• Table 4-1: Universal Adult Immunization Schedule 2006
• Table 4-2: Adult Immunization Schedule for Populations withSpecial Medical Conditions, 2006
• Table 4-3 : Selected Adult Preventive Vaccines in Development, 2007(Company, Product Name, Indication, Development Status)
• Table 4-4: World Market for Adult Preventive Vaccines by Type (Hepatitis,Influenza, Pneumococcal, Travel/DT/Misc.), 2003-2012
• Figure 4-1: Market Share of Adult Vaccines, by Type, 2005
• Figure 4-2: Market Share of Adult Vaccines, by Type, 2012
• Table 4-5: World Hepatitis Vaccine Market 2003-2012
• Table 4-6: World Influenza Vaccine Market 2003-2012
• Table 4-7: U.S. Influenza Vaccination Rates by Age and Risk Group 2004 - 2005
• Table 4-8: CDC Goal to Double Flu Immunization by 2010 Group and Estimated Immunization Rate (2000 vs 2010)
• Table 4-9: 2005 Estimated Population by Region and Selected AgeGroup Population
• Table 4-10: World Pneumococcal Vaccine Market 2003-2012Chapter Five: Preventive Vaccines Market Summary
• Figure 5-1: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market
• Table 5-1: The World Vaccines Market by Vaccine Type 2003-2012
• Figure 5-2: World Market for Vaccines Share by Type, 2003, 2007 and 2012
• Table 5-2: Major Manufacturers’ Shares of the World Vaccine Market, 2005
• Figure 5-3: 2005 World Vaccines Market Share, by Leading Competitors
• Table 5-3: Major Manufacturer’s Shares of the World PediatricVaccine Market 2005
• Figure 5-5: Market Share of Pediatric Vaccines Market, 2005
• Table 5-4: Major Manufacturer’s Shares of the World Adult Vaccine Market 2005
• Figure 5-6: Market Share of Adult Vaccines Market 2005

Chapter Six: Emerging Cancer Vaccines

• Table 6-1: Estimated and Projected World Cancer Incidence by Selected Types ofCancer (Lung, Breast, Colon/Rectum, Stomach, Liver, Prostate, Cervix,Esophogus, Lymphoma, Pancreas, Melanoma), 2005 and 2020
• Figure 6-1: Estimated and Projected World Cancer Incidence by SelectedTypes of Cancer, 2005 and 2020
• Table 6-2: Estimated and Projected World Cancer Mortality by Selected Types of Cancer (Lung, Breast, Colon/Rectum, Stomach, Liver, Prostate, Cervix, Esophogus, Lymphoma, Pancreas, Melanoma), 2005 and 2020
• Figure 6-2: Estimated and Projected World Cancer Mortality bySelected Types of Cancer
• Table 6-3: Total Cancer Incidence by Sex and Country,2006 Estimates (in thousands)
• Table 6-4: Estimated Cancer Incidence by World Region and Type of Cancer
• Figure 6-4: Estimated Cancer Incidence by World Regions
• Table 6-5: Malignant Conditions of the Skin
• Table 6-6: Types of Primary Lung Cancer, Risk Factors, Percent of Cases
• Table 6-7: Selected Cancer Vaccines in the Pipeline (Product Name, Developer,Indication, Development Phase, Earliest Approval Date)
• Table 6-8: World Market Cancer Vaccines by Cancer Type (Cervical,Colon/Rectal, Lung, Melanoma, Prostate, Other) 2003-2012
• Figure 6-5: Share of the Cancer Vaccine by Vaccine Indication, 2012

Chapter Seven: Issues and Trends

Table 7-1: Selected Companies/Laboratories Developing Biodefense Vaccines

 

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