Neuropathic Pain Insight - Life Beyond Gabapentin
The huge success of Pfizer's Neurontin (gabapentin) in the neuropathic pain market has encouraged drug manufacturers to explore the potential of their inline and pipeline products in this billion-dollar therapy area. Indeed, as gabapentin finally loses patent protection, and other companies launch products onto the market over the coming years, Pfizer will no longer control the sector.
Scope
· Quantitative treatment data from over 594 physicians: 80 from Japan, 82 from France, Germany, Italy, Spain and the UK, and 104 from the US
· For each country there is analysis of epidemiology, referral patterns, and treatment of five neuropathic pain types and fibromyalgia
· Physician perception of current treatments and identification of strategic issues including clinical trial design, unmet needs, and marketing
· Coverage of the hot topics including the 'indication versus symptoms' debate, generic gabapentin, opioid potential, and a focus on the future market
Highlights
The current neuropathic pain market suffers from lack of public awareness, poor physician education (often leading to misdiagnosis), under-utilization of effective drugs, inappropriate use of medications, and regional variations in drug availability.
Despite considerable sales deriving from diabetic neuropathic pain prescriptions, gabapentin does not benefit from FDA approval, offering opportunities to new market entrants. Several companies are battling to be first-to-market, although Datamonitor expects Pfizer will enjoy this status when its follow-on drug, pregabalin, launches in 2004.
The FDA strategy to grant narrow indications only is not entirely limiting from a commercial perspective. Datamonitor believes a narrowly defined indication offers three main advantages: a focused market; greater ability to dominate one indication; the ability to extend the lifecycle of the product with further indications.
Reasons to Purchase
· Gain a better understanding of the challenges faced by existing and future players in the neuropathic pain market
· Discover how the FDA policy of approving drugs only for narrow indications can work to your advantage
· Target lucrative areas of the market as defined by physicians, such as fibromyalgia, and understand why these areas offer commercial opportunity
Table of Contents
- CHAPTER 1 EXECUTIVE SUMMARY - page 3
- 1.1 Scope of the Analysis - page 3
- 1.2 Datamonitor insight into neuropathic pain - page 3
- The current neuropathic pain market suffers from lack of public awareness, poor physician education (often leading to misdiagnosis), under-utilization of effective drugs, inappropriate use of medications, and regional variations in drug availability. Datamonitor believes these are but some of the challenges facing existing and future players in the market. - page 5
- Although frequently managed with the same treatments, Datamonitor believes it is important that investors are aware of the opportunities and drawbacks of key subtypes in order to optimize product positioning and marketing strategies. Particularly as this aligns with the FDA licensing strategy. - page 8
- Datamonitor believes the 'indication versus symptoms' debate is one of the most important issues in the current market. Datamonitor recommends existing and potential players consider the pros and cons of regulatory agency viewpoint and rulings across the seven major markets. - page 13
- Aggressive promotional campaigns and astute marketing and product positioning strategies will ensure branded products can dominate the market. With generic gabapentin entering the market, more than ever companies need to be innovative to effectively define and 'own' a market. Datamonitor has identified several realistic ways of differentiating a new product from gabapentin. - page 17
- The neuropathic market will continue to grow unabated over the next ten years primarily due to increased public and physician awareness and new drug launches. Pfizer is expected to continue leading the market in terms of revenues with new entrant pregabalin. However, competition will be strong as several top-tier players aim to enter the market with novel and existing compounds. - page 19
- 1.3 Neuropathic Pain Insight: methodology - page 20
- TABLE OF CONTENTS - page 22
- CHAPTER 2 COMPARATIVE ANALYSIS - page 56
- 2.1 Introduction - page 57
- Summary - page 58
- 2.2 Sample - page 59
- 2.3 Definition and clinical features of neuropathic pain - page 59
- Introduction - page 59
- Etiology - page 60
- Diabetic neuropathic pain - page 61
- Trigeminal neuralgia - page 61
- Post-herpetic neuralgia - page 61
- Neuropathic low-back pain - page 62
- Fibromyalgia - page 62
- HIV neuropathic pain - page 64
- 2.4 Overall Epidemiology - page 65
- Overview of total neuropathic pain - page 65
- 2.5 Diagnosis and assessment - page 66
- Breakdown of diagnosis by physician type - page 67
- 2.6 Overview of neuropathic pain treatment - page 68
- Introduction - page 68
- Pharmacotherapy - page 69
- 2.7 Treatment of neuropathic pain - page 73
- Importance of therapeutic endpoints on prescribing decisions - page 73
- Summary of neuropathic treatment in the seven major markets - page 74
- First-line therapy - page 75
- Second-line therapy - page 76
- Third-line therapy - page 77
- Summary of treatment-Country comparison - page 78
- Summary of treatment-Indication comparison - page 83
- Combination therapy - page 89
- The commercial potential of interventional techniques in neuropathic pain - page 92
- 2.8 Drug Analysis - page 94
- Symptoms of neuropathic pain - page 94
- Non-symptom attributes in neuropathic pain - page 96
- Drug attributes - page 98
- Drug profiles - page 99
- Physician awareness of pipeline products - page 111
- 2.9 Strategic Issues In Neuropathic Pain - page 118
- Clinical trial design - page 118
- Indications versus symptoms - page 121
- Unmet needs - page 126
- Marketing neuropathic pain compounds - page 128
- 2.1 Introduction - page 57
- CHAPTER 3 THE US MARKET - page 130
- Summary - page 131
- 3.1 Sample - page 132
- 3.2 Overall Epidemiology - page 133
- Overview of total neuropathic pain - page 133
- Breakdown of diagnosis by physician type - page 133
- 3.3 Diabetic Neuropathic Pain - page 135
- Epidemiology - page 135
- Referral & assessment - page 137
- Breakdown by severity - page 138
- Treatment of diabetic neuropathy - page 139
- 3.4 Trigeminal Neuralgia - page 149
- Epidemiology - page 149
- Referral & assessment - page 150
- Breakdown by severity - page 150
- Treatment of trigeminal neuralgia - page 152
- 3.5 Post-herpetic neuralgia - page 159
- Epidemiology - page 159
- Referral & assessment - page 161
- Breakdown by severity - page 162
- Treatment of post-herpetic neuralgia - page 163
- 3.6 Neuropathic low-back pain - page 169
- Epidemiology - page 169
- Referral & assessment - page 170
- Breakdown by severity - page 171
- Treatment of neuropathic low-back pain - page 173
- 3.7 Fibromyalgia - page 181
- Epidemiology - page 181
- Referral & assessment - page 182
- Breakdown by severity - page 183
- Treatment of fibromyalgia - page 184
- 3.8 HIV neuropathic pain - page 192
- Epidemiology - page 192
- Referral & assessment - page 192
- Breakdown by severity - page 193
- Treatment of HIV neuropathic pain - page 195
- 3.9 Drug Analysis - page 201
- Symptoms of neuropathic pain - page 201
- Non-symptom attributes in neuropathic pain - page 202
- Drug attributes - page 203
- Drug profiles - page 204
- Combination therapy - page 208
- Pipeline products - page 210
- 3.10 Strategic Issues In Neuropathic Pain - page 214
- New treatment guidelines define five first-line therapies - page 214
- Clinical trial design - page 217
- Indications versus symptoms - page 218
- Unmet needs - page 222
- Marketing neuropathic pain compounds - page 223
- CHAPTER 4 THE JAPANESE MARKET - page 225
- Summary - page 226
- 4.1 Sample - page 227
- 4.2 Overall Epidemiology - page 228
- Overview of total neuropathic pain - page 228
- Breakdown of diagnosis by physician type - page 229
- 4.3 Diabetic Neuropathic Pain - page 231
- Epidemiology - page 231
- Referral & assessment - page 231
- Breakdown by severity - page 232
- Treatment of diabetic neuropathy - page 234
- 4.4 Trigeminal Neuralgia - page 240
- Epidemiology - page 240
- Referral & assessment - page 241
- Breakdown by severity - page 241
- Treatment of trigeminal neuralgia - page 242
- 4.5 Post-herpetic neuralgia - page 248
- Epidemiology - page 248
- Referral & assessment - page 248
- Breakdown by severity - page 249
- Treatment of post-herpetic neuralgia - page 250
- 4.6 Neuropathic low-back pain - page 256
- Epidemiology - page 256
- Referral & assessment - page 256
- Breakdown by severity - page 257
- Treatment of neuropathic low-back pain - page 258
- 4.7 Fibromyalgia - page 263
- Epidemiology - page 263
- Referral & assessment - page 263
- Breakdown by severity - page 265
- Treatment of fibromyalgia - page 266
- 4.8 Drug Analysis - page 272
- Symptoms of neuropathic pain - page 272
- Non-symptom attributes in neuropathic pain - page 273
- Drug attributes - page 276
- Drug profiles - page 277
- Combination therapy - page 280
- Pipeline products - page 282
- 4.9 Strategic Issues In Neuropathic Pain - page 284
- Clinical trial design - page 284
- Unmet needs - page 287
- Marketing neuropathic pain compounds - page 288
- CHAPTER 5 THE FRENCH MARKET - page 289
- Summary - page 290
- 5.1 Sample - page 291
- 5.2 Overall Epidemiology - page 292
- Overview of total neuropathic pain - page 292
- Breakdown of diagnosis by physician type - page 292
- 5.3 Diabetic Neuropathic Pain - page 294
- Epidemiology - page 294
- Referral & assessment - page 294
- Breakdown by severity - page 295
- Treatment of diabetic neuropathy - page 296
- 5.4 Trigeminal Neuralgia - page 302
- Epidemiology - page 302
- Referral & assessment - page 303
- Breakdown by severity - page 303
- Treatment of trigeminal neuralgia - page 305
- 5.5 Post-herpetic neuralgia - page 309
- Epidemiology - page 309
- Referral & assessment - page 310
- Breakdown by severity - page 310
- Treatment of post-herpetic neuralgia - page 311
- 5.6 Neuropathic low-back pain - page 316
- Epidemiology - page 316
- Referral & assessment - page 317
- Breakdown by severity - page 317
- Treatment of neuropathic low-back pain - page 318
- 5.7 Fibromyalgia - page 324
- Epidemiology - page 324
- Referral & assessment - page 324
- Breakdown by severity - page 326
- Unmet needs in fibromyalgia as identified by opinion leaders - page 327
- Treatment of fibromyalgia - page 328
- 5.8 HIV neuropathic pain - page 335
- Epidemiology - page 335
- Referral & assessment - page 336
- Breakdown by severity - page 336
- Treatment of HIV neuropathic pain - page 337
- 5.9 Drug Analysis - page 343
- Symptoms of neuropathic pain - page 343
- Non-symptom attributes of neuropathic pain - page 344
- Drug attributes - page 346
- Drug profiles - page 346
- Combination therapy - page 350
- Pipeline products - page 350
- 5.10 Strategic Issues In Neuropathic Pain - page 352
- The impact of guidelines in France - page 352
- Clinical trial design - page 353
- Unmet needs - page 356
- Marketing neuropathic pain compounds - page 357
- CHAPTER 6 THE GERMAN MARKET - page 359
- Summary - page 360
- 6.1 Sample - page 361
- 6.2 Overall Epidemiology - page 362
- Overview of total neuropathic pain - page 362
- Breakdown of diagnosis by physician type - page 362
- 6.3 Diabetic Neuropathic Pain - page 365
- Epidemiology - page 365
- Referral & assessment - page 365
- Breakdown by severity - page 366
- Treatment of diabetic neuropathy - page 367
- 6.4 Trigeminal Neuralgia - page 374
- Epidemiology - page 374
- Referral & assessment - page 374
- Breakdown by severity - page 375
- Treatment of trigeminal neuralgia - page 376
- 6.5 Post-herpetic neuralgia - page 382
- Epidemiology - page 382
- Referral & assessment - page 382
- Breakdown by severity - page 383
- Treatment of post-herpetic neuralgia - page 384
- 6.6 Neuropathic low-back pain - page 390
- Epidemiology - page 390
- Referral & assessment - page 391
- Breakdown by severity - page 392
- Treatment of neuropathic low-back pain - page 393
- 6.7 Fibromyalgia - page 398
- Epidemiology - page 398
- Referral & assessment - page 399
- Breakdown by severity - page 399
- Treatment of fibromyalgia - page 401
- 6.8 HIV neuropathic pain - page 408
- Epidemiology - page 408
- Referral & assessment - page 408
- Breakdown by severity - page 409
- Treatment of HIV neuropathic pain - page 411
- 6.9 Drug Analysis - page 415
- Symptoms of neuropathic pain - page 415
- Non-symptom attributes in neuropathic pain - page 416
- Drug attributes - page 418
- Drug profiles - page 418
- Combination therapy - page 421
- Pipeline products - page 422
- 6.10 Strategic Issues In Neuropathic Pain - page 424
- Current guidelines have little influence - page 424
- The German Research Network on Neuropathic Pain - page 424
- Clinical trial design - page 425
- Unmet needs - page 428
- Marketing neuropathic pain compounds - page 430
- CHAPTER 7 THE ITALIAN MARKET - page 432
- Summary - page 433
- 7.1 Sample - page 434
- 7.2 Overall Epidemiology - page 435
- Overview of total neuropathic pain - page 435
- Breakdown of diagnosis by physician type - page 435
- 7.3 Diabetic Neuropathic Pain - page 437
- Epidemiology - page 437
- Referral & assessment - page 437
- Breakdown by severity - page 438
- Treatment of diabetic neuropathy - page 439
- 7.4 Trigeminal Neuralgia - page 445
- Epidemiology - page 445
- Referral & assessment - page 445
- Breakdown by severity - page 446
- Treatment of trigeminal neuralgia - page 447
- 7.5 Post-herpetic neuralgia - page 452
- Epidemiology - page 452
- Referral & assessment - page 452
- Breakdown by severity - page 453
- Treatment of post-herpetic neuralgia - page 454
- 7.6 Neuropathic low-back pain - page 460
- Epidemiology - page 460
- Referral & assessment - page 460
- Breakdown by severity - page 461
- Treatment of neuropathic low-back pain - page 462
- 7.7 Fibromyalgia - page 466
- Epidemiology - page 466
- Referral & assessment - page 467
- Breakdown by severity - page 468
- Treatment of fibromyalgia - page 469
- 7.8 HIV neuropathic pain - page 475
- Epidemiology - page 475
- Referral & assessment - page 475
- Breakdown by severity - page 476
- Treatment of HIV neuropathic pain - page 477
- 7.9 Drug Analysis - page 482
- Symptoms of neuropathic pain - page 482
- Non-symptom attributes in neuropathic pain - page 483
- Drug attributes - page 484
- Drug profiles - page 485
- Combination therapy - page 489
- Pipeline products - page 489
- 7.10 Strategic Issues In Neuropathic Pain - page 492
- Clinical trial design - page 492
- Unmet needs - page 495
- Marketing neuropathic pain compounds - page 498
- CHAPTER 8 THE SPANISH MARKET - page 499
- Summary - page 500
- 8.1 Sample - page 501
- 8.2 Overall Epidemiology - page 502
- Overview of total neuropathic pain - page 502
- Breakdown of diagnosis by physician type - page 502
- 8.3 Diabetic Neuropathic Pain - page 504
- Epidemiology - page 504
- Referral & assessment - page 504
- Breakdown by severity - page 505
- Treatment of diabetic neuropathy - page 506
- 8.4 Trigeminal Neuralgia - page 511
- Epidemiology - page 511
- Referral & assessment - page 512
- Breakdown by severity - page 512
- Treatment of trigeminal neuralgia - page 513
- 8.5 Post-herpetic neuralgia - page 517
- Epidemiology - page 517
- Referral & assessment - page 518
- Breakdown by severity - page 519
- Treatment of post-herpetic neuralgia - page 520
- 8.6 Neuropathic low-back pain - page 525
- Epidemiology - page 525
- Referral & assessment - page 526
- Breakdown by severity - page 527
- Treatment of neuropathic low-back pain - page 528
- 8.7 Fibromyalgia - page 533
- Epidemiology - page 533
- Referral & assessment - page 534
- Breakdown by severity - page 535
- Treatment of fibromyalgia - page 536
- 8.8 HIV neuropathic pain - page 541
- Epidemiology - page 541
- Referral & assessment - page 542
- Treatment of HIV neuropathic pain - page 542
- 8.9 Drug Analysis - page 542
- Symptoms of neuropathic pain - page 542
- Non-symptom attributes in neuropathic pain - page 544
- Drug attributes - page 545
- Drug profiles - page 545
- Combination therapy - page 548
- Pipeline products - page 549
- 8.10 Strategic Issues In Neuropathic Pain - page 550
- Clinical trial design - page 550
- Unmet needs - page 552
- Marketing neuropathic pain compounds - page 554
- CHAPTER 9 THE UK MARKET - page 556
- Summary - page 557
- 9.1 Sample - page 558
- 9.2 Overall Epidemiology - page 559
- Overview of total neuropathic pain - page 559
- Breakdown of diagnosis by physician type - page 560
- 9.3 Diabetic Neuropathic Pain - page 561
- Epidemiology - page 561
- Referral & assessment - page 562
- Breakdown by severity - page 563
- Treatment of diabetic neuropathy - page 564
- 9.4 Trigeminal Neuralgia - page 570
- Epidemiology - page 570
- Referral & assessment - page 570
- Breakdown by severity - page 571
- Treatment of trigeminal neuralgia - page 572
- 9.5 Post-herpetic neuralgia - page 576
- Epidemiology - page 576
- Referral & assessment - page 577
- Breakdown by severity - page 578
- Treatment of post-herpetic neuralgia - page 579
- 9.6 Neuropathic low-back pain - page 585
- Epidemiology - page 585
- Referral & assessment - page 587
- Breakdown by severity - page 589
- Treatment of neuropathic low-back pain - page 590
- 9.7 Fibromyalgia - page 595
- Epidemiology - page 595
- Referral & assessment - page 595
- Breakdown by severity - page 597
- Treatment of fibromyalgia - page 598
- 9.8 HIV neuropathic pain - page 602
- Epidemiology - page 602
- Referral & assessment - page 603
- Breakdown by severity - page 604
- Treatment of HIV neuropathic pain - page 605
- 9.9 Drug Analysis - page 612
- Symptoms of neuropathic pain - page 612
- Non-symptom attributes in neuropathic pain - page 613
- Drug attributes - page 614
- Drug profiles - page 615
- Combination therapy - page 618
- Pipeline products - page 620
- 9.10 Strategic Issues In Neuropathic Pain - page 621
- Clinical trial design - page 621
- Unmet needs - page 622
- Marketing neuropathic pain compounds - page 624
- CHAPTER 10 APPENDIX A - page 626
- 10.1 Bibliography - page 626
- References - page 626
- Websites - page 638
- 10.2 Drug profile tables - page 640
- 10.3 Contributing experts - page 643
- Neuropathic pain experts - page 644
- Diabetic neuropathic pain experts - page 645
- Post-herpetic neuralgia experts - page 646
- Neuropathic low-back pain experts - page 646
- Fibromyalgia experts - page 646
- HIV neuropathic pain experts - page 647
- 10.4 Physician research methodology - page 647
- Introduction - page 647
- Our research partners - page 649
- Research objectives - page 649
- Questionnaire development - page 651
- Research methodology - page 652
- Data processing - page 654
- Quality control - page 655
- 10.5 Neuropathic Pain Insight Questionnaire - page 655
- 10.1 Bibliography - page 626
- CHAPTER 11 APPENDIX B - page 670
- 11.1 About Datamonitor - page 670
- About Datamonitor Healthcare - page 670
- Datamonitor Healthcare's research and analysis methodologies - page 671
- 11.2 Datamonitor Healthcare's therapy area capabilities - page 671
- About the CNS analysis team - page 672
- Datamonitor Healthcare's Consulting expertise - page 673
- Key therapy team members - page 674
- About the Author - page 675
- Disclaimer - page 677
- 11.1 About Datamonitor - page 670
- List of Tables
- Table 1: Sample size of the Neuropathic Pain Insight Study sample, 2003 - page 20
- Table 2: Sample size of the Neuropathic Pain Insight Study, 2003 - page 59
- Table 3: Prevalence (000s) of key neuropathic pain subtypes, 2003 - page 66
- Table 4: Influence of symptom-based efficacy attributes on drug choice for neuropathic pain, 2003 - page 95
- Table 5: Influence of non-symptom therapy impacts on drug choice for neuropathic pain, 2003 - page 97
- Table 6: Key facts about Neurontin - page 103
- Table 7: Strengths and weaknesses of gabapentin for neuropathic pain treatment, according to interviewed physicians, 2003 - page 103
- Table 8: Key facts about Lidoderm - page 105
- Table 9: Strengths and weaknesses of lidocaine patch for neuropathic pain treatment, according to interviewed physicians, 2003 - page 106
- Table 10: Strengths and weaknesses of opioids for neuropathic pain treatment, according to interviewed physicians, 2003 - page 107
- Table 11: Strengths and weaknesses of amitriptyline for neuropathic pain treatment, according to interviewed physicians, 2003 - page 110
- Table 12: R&D compounds for neuropathic pain, 2004 - page 112
- Table 13: Drugs in late-stage development for neuropathic pain, 2004 - page 113
- Table 14: Six unmet needs in the treatment of neuropathic pain as identified and ranked by physicians across the seven markets, 2003 - page 126
- Table 15: Top five sources of neuropathic pain information by physician type and country, 2003 - page 129
- Table 16: Sample details for the US neuropathic pain survey, 2003 - page 132
- Table 17: Breakdown of neuropathic pain subtypes in the US, 2003 - page 134
- Table 18: The DNP patient population in the US, 2003 - page 136
- Table 19: Referral patterns of DNP patients in the US, 2003 - page 138
- Table 20: Breakdown of DNP patients by pain severity according to the physician type treating them in the US, 2003 - page 138
- Table 21: Importance of key therapeutic endpoints in DNP according to US physicians, 2003 - page 140
- Table 22: Top ten most widely adopted first-line treatments of DNP in the US, 2003 - page 143
- Table 23: Progression of DNP patients to second-line therapy in the US, 2003 - page 146
- Table 24: Top ten most widely adopted second-line treatments of DNP in the US, 2003 - page 147
- Table 25: Progression of DNP patients to third-line therapy in the US, 2003 - page 148
- Table 26: Top ten most widely adopted third-line treatments of DNP in the US, 2003 - page 148
- Table 27: The TN patient population in the US, 2003 - page 149
- Table 28: Referral patterns of TN patients in the US, 2003 - page 150
- Table 29: Breakdown of TN patients by pain severity according to the physician type treating them in the US, 2003 - page 151
- Table 30: Importance of key therapeutic endpoints in TN according to US physicians, 2003 - page 152
- Table 31: Top ten most widely adopted first-line treatments of TN in the US, 2003 - page 155
- Table 32: Progression of TN patients to second-line therapy in the US, 2003 - page 157
- Table 33: Top ten most widely adopted second-line treatments of TN in the US, 2003 - page 157
- Table 34: Progression of TN patients to third-line therapy in the US, 2003 - page 158
- Table 35: Top ten third-line treatments of TN in the US, 2003 - page 158
- Table 36: Prevalence of PHN in a group of patients at three stages in a twelve month period - page 160
- Table 37: The prevalence at one month, three months and 12 months of PHN in patients with HZ split by age group - page 160
- Table 38: Prevalence of PHN at one month after detection of herpes zoster in the US, 2003 - page 161
- Table 39: Referral patterns of PHN patients in the US, 2003 - page 161
- Table 40: Breakdown of PHN patients by pain severity according to the physician type treating them in the US, 2003 - page 162
- Table 41: Importance of key therapeutic endpoints in PHN according to US physicians, 2003 - page 164
- Table 42: Top ten most widely adopted first-line treatments of PHN in the US, 2003 - page 165
- Table 43: Progression of PHN patients to second-line therapy in the US, 2003 - page 167
- Table 44: Top ten most widely adopted second-line treatments of PHN in the US, 2003 - page 168
- Table 45: Progression of PHN patients to third-line therapy in the US, 2003 - page 168
- Table 46: Top ten most widely adopted third-line treatments of PHN in the US, 2003 - page 169
- Table 47: The NLBP patient population in the US, 2003 - page 169
- Table 48: Referral patterns of NLBP patients in the US, 2003 - page 171
- Table 49: Breakdown of NLBP patients by pain severity according to the physician type treating them in the US, 2003 - page 172
- Table 50: Importance of key therapeutic endpoints in NLBP according to US physicians, 2003 - page 173
- Table 51: Top ten first-line treatments of NLBP in the US, 2003 - page 176
- Table 52: Progression of NLBP patients to second-line therapy in the US, 2003 - page 179
- Table 53: Top ten most widely adopted second-line treatments of NLBP in the US, 2003 - page 179
- Table 54: Progression of NLBP patients to third-line therapy in the US, 2003 - page 180
- Table 55: Top ten most widely adopted third-line treatments of NLBP in the US, 2003 - page 180
- Table 56: The fibromyalgia patient population in the US, 2003 - page 181
- Table 57: Referral patterns of fibromyalgia patients in the US, 2003 - page 183
- Table 58: Breakdown of fibromyalgia patients by severity according to the physician type treating them in the US, 2003 - page 183
- Table 59: Importance of key therapeutic endpoints in fibromyalgia according to US physicians, 2003 - page 185
- Table 60: Top ten most widely adopted first-line treatments of fibromyalgia in the US, 2003 - page 188
- Table 61: Progression of fibromyalgia patients to second-line therapy in the US, 2003 - page 190
- Table 62: Top ten most widely adopted second-line treatments of fibromyalgia in the US, 2003 - page 190
- Table 63: Progression of fibromyalgia patients to third-line therapy in the US, 2003 - page 191
- Table 64: Top ten most widely adopted third-line treatments of fibromyalgia in the US, 2003 - page 191
- Table 65: The HIVNP patient population in the US, 2004 - page 192
- Table 66: Referral patterns of HIVNP patients in the US, 2003 - page 193
- Table 67: Breakdown of HIVNP patients by pain severity according to the physician type treating them in the US, 2003 - page 193
- Table 68: Importance of key therapeutic endpoints in HIVNP according to US physicians, 2003 - page 195
- Table 69: Top ten first-line treatments of HIVNP in the US, 2003 - page 198
- Table 70: Progression of HIVNP patients to second-line therapy in the US, 2003 - page 199
- Table 71: Top ten most widely adopted second-line treatments of HIVNP in the US, 2003 - page 199
- Table 72: Progression of HIVNP patients to third-line therapy in the US, 2003 - page 200
- Table 73: Top ten most widely adopted third-line treatments of HIVNP in the US, 2003 - page 200
- Table 74: Influence of efficacy attributes on drug choice for neuropathic pain in the US, 2003 - page 201
- Table 75: Influence of non-symptom therapy impacts on drug choice for neuropathic pain in the US, 2003 - page 203
- Table 76: Importance of broader drug attributes on therapy choice for neuropathic pain in the US, 2003 - page 204
- Table 77: Top ten drug combinations for neuropathic pain in the US, 2003 - page 209
- Table 78: US physician awareness of neuropathic drugs In development, 2003 - page 211
- Table 79: First-line recommendations for neuropathic pain - page 215
- Table 80: Influence of clinical trial design on drug choice in the US, 2003 - page 217
- Table 81: Specific indications versus specific symptoms of neuropathic pain for drug trials in the US, 2003 - page 220
- Table 82: Six major unmet needs in the treatment of neuropathic pain as identified and ranked by US physicians, 2003 - page 222
- Table 83: How physicians get information for neuropathic pain in the US, 2003 - page 223
- Table 84: Sample details for the Japan neuropathic pain survey, 2003 - page 227
- Table 85: Breakdown of neuropathic pain subtypes in Japan, 2003 - page 229
- Table 86: The DNP patient population in Japan, 2003 - page 231
- Table 87: Referral patterns of DNP patients in Japan, 2003 - page 232
- Table 88: Breakdown of DNP patients by pain severity according to the physician type treating them in Japan, 2003 - page 232
- Table 89: Importance of key therapeutic endpoints in DNP according to physicians in Japan, 2003 - page 234
- Table 90: Top ten most widely adopted first-line treatments of DNP in Japan, 2003 - page 236
- Table 91: Progression of DNP patients to second-line therapy in Japan, 2003 - page 238
- Table 92: Top ten most widely adopted second-line treatments of DNP in Japan, 2003 - page 239
- Table 93: Progression of DNP patients to third-line therapy in Japan, 2003 - page 239
- Table 94: Top ten most widely adopted third-line treatments of DNP in Japan, 2003 - page 240
- Table 95: The TN patient population in Japan, 2003 - page 240
- Table 96: Referral patterns of TN patients in Japan, 2003 - page 241
- Table 97: Breakdown of TN patients by pain severity according to the physician type treating them in Japan, 2003 - page 241
- Table 98: Importance of key therapeutic endpoints in TN according to physicians in Japan, 2003 - page 243
- Table 99: Top ten most widely adopted first-line treatments of TN in Japan, 2003 - page 245
- Table 100: Progression of TN patients to second-line therapy in Japan, 2003 - page 246
- Table 101: Top ten most widely adopted second-line treatments of TN in Japan, 2003 - page 246
- Table 102: Progression of TN patients to third-line therapy in Japan, 2003 - page 247
- Table 103: Top ten most widely adopted third-line treatments of TN in Japan, 2003 - page 247
- Table 104: Prevalence of PHN at one month after detection of herpes zoster in Japan, 2003 - page 248
- Table 105: Referral patterns of PHN patients in Japan, 2003 - page 248
- Table 106: Breakdown of PHN patients by pain severity according to the physician type treating them in Japan, 2003 - page 249
- Table 107: Importance of key therapeutic endpoints in PHN according to physicians in Japan, 2003 - page 250
- Table 108: Top ten most widely adopted first-line treatments of PHN in Japan, 2003 - page 252
- Table 109: Progression of PHN patients to second-line therapy in Japan, 2003 - page 254
- Table 110: Top ten most widely adopted second-line treatments of PHN in Japan, 2003 - page 254
- Table 111: Progression of PHN patients to third-line therapy in Japan, 2003 - page 255
- Table 112: Top ten most widely adopted third-line treatments of PHN in Japan, 2003 - page 255
- Table 113: The NLBP patient population in Japan, 2003 - page 256
- Table 114: Referral patterns of NLBP patients in Japan, 2003 - page 256
- Table 115: Breakdown of NLBP patients by pain severity according to the physician type treating them in Japan, 2003 - page 257
- Table 116: Importance of key therapeutic endpoints in NLBP according to physicians in Japan, 2003 - page 258
- Table 117: Top ten first-line treatments of NLBP in Japan, 2003 - page 260
- Table 118: Progression of NLBP patients to second-line therapy in Japan, 2003 - page 260
- Table 119: Top ten most widely adopted second-line treatments of NLBP in Japan, 2003 - page 261
- Table 120: Progression of NLBP patients to third-line therapy in Japan, 2003 - page 261
- Table 121: Top ten most widely adopted third-line treatments of NLBP in Japan, 2003 - page 262
- Table 122: The fibromyalgia patient population in Japan, 2003 - page 263
- Table 123: Referral patterns of fibromyalgia patients in Japan, 2003 - page 264
- Table 124: Breakdown of fibromyalgia patients by severity according to the physician type treating them in Japan, 2003 - page 265
- Table 125: Importance of key therapeutic endpoints in fibromyalgia according to physicians in Japan, 2003 - page 266
- Table 126: Top ten first-line treatments of fibromyalgia in Japan, 2003 - page 269
- Table 127: Progression of fibromyalgia patients to second-line therapy in Japan, 2003 - page 270
- Table 128: Top ten most widely adopted second-line treatments of fibromyalgia in Japan, 2003 - page 270
- Table 129: Progression of fibromyalgia patients to third-line therapy in Japan, 2003 - page 271
- Table 130: Top ten most widely adopted third-line treatments of fibromyalgia in Japan, 2003 - page 271
- Table 131: Influence of efficacy attributes on drug choice for neuropathic pain in Japan, 2003 - page 272
- Table 132: Influence of non-symptom therapy impacts on drug choice for neuropathic pain in Japan, 2003 - page 274
- Table 133: Importance of broader drug attributes on therapy choice for neuropathic pain in Japan, 2003 - page 276
- Table 134: Top ten drug combinations for neuropathic pain in Japan, 2003 - page 281
- Table 135: Physician awareness of neuropathic drugs in development in Japan, 2003 - page 282
- Table 136: Influence of clinical trial design on drug choice in Japan, 2003 - page 284
- Table 137: Specific indications versus specific symptoms of neuropathic pain for drug trials in Japan, 2003 - page 286
- Table 138: Six major unmet needs in the treatment of neuropathic pain as identified and ranked by physicians in Japan, 2003 - page 287
- Table 139: How physicians get information for neuropathic pain in Japan, 2003 - page 288
- Table 140: Sample details for the France neuropathic pain survey, 2003 - page 291
- Table 141: Breakdown of neuropathic pain subtypes in France, 2003 - page 293
- Table 142: The DNP patient population in France, 2003 - page 294
- Table 143: Referral patterns of DNP patients in France, 2003 - page 295
- Table 144: Breakdown of DNP patients by pain severity according to the physician type treating them in France, 2003 - page 295
- Table 145: Importance of key therapeutic endpoints in DNP in France, 2003 - page 297
- Table 146: Top most widely adopted first-line treatments of DNP in France, 2003 - page 299
- Table 147: Progression of DNP patients to second-line therapy in France, 2003 - page 300
- Table 148: Top ten most widely adopted second-line treatments of DNP in France, 2003 - page 301
- Table 149: Progression of DNP patients to third-line therapy in France, 2003 - page 301
- Table 150: Top ten most widely adopted third-line treatments of DNP in France, 2003 - page 302
- Table 151: The TN patient population in France, 2003 - page 302
- Table 152: Referral patterns of TN patients in France, 2003 - page 303
- Table 153: Breakdown of TN patients by pain severity according to the physician type treating them in France, 2003 - page 304
- Table 154: Importance of key therapeutic endpoints in TN according to physicians in France, 2003 - page 305
- Table 155: Top most widely adopted first-line treatments of TN in France, 2003 - page 306
- Table 156: Progression of TN patients to second-line therapy in France, 2003 - page 307
- Table 157: Top ten most widely adopted second-line treatments of TN in France, 2003 - page 307
- Table 158: Progression of TN patients to third-line therapy in France, 2003 - page 308
- Table 159: Top ten most widely adopted third-line treatments of TN in France, 2003 - page 308
- Table 160: Prevalence of PHN at one month after detection of herpes zoster in France, 2003 - page 309
- Table 161: Referral patterns of PHN patients in France, 2003 - page 310
- Table 162: Breakdown of PHN patients by pain severity according to the physician type treating them in France, 2003 - page 310
- Table 163: Importance of key therapeutic endpoints in PHN according to physicians in France, 2003 - page 311
- Table 164: Top ten most widely adopted first-line treatments of PHN in France, 2003 - page 313
- Table 165: Progression of PHN patients to second-line therapy in France, 2003 - page 314
- Table 166: Top ten most widely adopted second-line treatments of PHN in France, 2003 - page 315
- Table 167: Progression of PHN patients to third-line therapy in France, 2003 - page 315
- Table 168: Top ten most widely adopted third-line treatments of PHN in France, 2003 - page 316
- Table 169: The NLBP patient population in France, 2003 - page 316
- Table 170: Referral patterns of NLBP patients in France, 2003 - page 317
- Table 171: Breakdown of NLBP patients by pain severity according to the physician type treating them in France, 2003 - page 318
- Table 172: Importance of key therapeutic endpoints in NLBP according to physicians in France, 2003 - page 319
- Table 173: Top ten first-line treatments of NLBP in France, 2003 - page 321
- Table 174: Progression of NLBP patients to second-line therapy in France, 2003 - page 322
- Table 175: Top ten most widely adopted second-line treatments of NLBP in France, 2003 - page 322
- Table 176: Progression of NLBP patients to third-line therapy in France, 2003 - page 323
- Table 177: Top ten most widely adopted third-line treatments of NLBP in France, 2003 - page 323
- Table 178: The fibromyalgia patient population in France, 2003 - page 324
- Table 179: Referral patterns of fibromyalgia patients in France, 2003 - page 324
- Table 180: Breakdown of fibromyalgia patients by severity according to the physician type treating them in France, 2003 - page 326
- Table 181: Importance of key therapeutic endpoints in fibromyalgia according to physicians in France, 2003 - page 328
- Table 182: Top ten first-line treatments of fibromyalgia in France, 2003 - page 331
- Table 183: Progression of fibromyalgia patients to second-line therapy in France, 2003 - page 332
- Table 184: Top ten most widely adopted second-line treatments of fibromyalgia in France, 2003 - page 333
- Table 185: Progression of fibromyalgia patients to third-line therapy in France, 2003 - page 334
- Table 186: Top ten most widely adopted third-line treatments of fibromyalgia in France, 2003 - page 335
- Table 187: The HIVNP patient population in France, 2004 - page 335
- Table 188: Referral patterns of HIVNP patients in France, 2003 - page 336
- Table 189: Breakdown of HIVNP patients by pain severity according to the physician type treating them in France, 2003 - page 337
- Table 190: Importance of key therapeutic endpoints in HIVNP according to physicians in France, 2003 - page 338
- Table 191: Top ten first-line treatments of HIVNP in France, 2003 - page 340
- Table 192: Progression of HIVNP patients to second-line therapy in France, 2003 - page 340
- Table 193: Top ten most widely adopted second-line treatments of HIVNP in France, 2003 - page 341
- Table 194: Progression of HIVNP patients to third-line therapy in France, 2003 - page 341
- Table 195: Top ten most widely adopted third-line treatments of HIVNP in France, 2003 - page 342
- Table 196: Influence of efficacy attributes on drug choice for neuropathic pain in France, 2003 - page 343
- Table 197: Influence of non-symptom therapy impacts on drug choice for neuropathic pain in France, 2003 - page 345
- Table 198: Importance of broader drug attributes on therapy choice for neuropathic pain in France, 2003 - page 346
- Table 199: Top ten drug combinations for neuropathic pain in France, 2003 - page 350
- Table 200: France physician awareness of neuropathic drugs In development, 2003 - page 351
- Table 201: Influence of clinical trial design on drug choice in France, 2003 - page 353
- Table 202: Specific indications versus specific symptoms of neuropathic pain for drug trials in France, 2003 - page 354
- Table 203: Six major unmet needs in the treatment of neuropathic pain as identified and ranked by physicians in France, 2003 - page 356
- Table 204: How physicians get information for neuropathic pain in France, 2003 - page 357
- Table 205: Sample details for the Germany neuropathic pain survey, 2003 - page 361
- Table 206: Breakdown of neuropathic pain subtypes in Germany, 2003 - page 363
- Table 207: The DNP patient population in Germany, 2003 - page 365
- Table 208: Referral patterns of DNP patients in Germany, 2003 - page 366
- Table 209: Breakdown of DNP patients by pain severity according to the physician type treating them in Germany, 2003 - page 366
- Table 210: Importance of key therapeutic endpoints in DNP according to physicians in Germany, 2003 - page 368
- Table 211: Top ten most widely adopted first-line treatments of DNP in Germany, 2003 - page 370
- Table 212: Progression of DNP patients to second-line therapy in Germany, 2003 - page 372
- Table 213: Top ten most widely adopted second-line treatments of DNP in Germany, 2003 - page 372
- Table 214: Progression of DNP patients to third-line therapy in Germany, 2003 - page 373
- Table 215: Top ten most widely adopted third-line treatments of DNP in Germany, 2003 - page 373
- Table 216: The TN patient population in Germany, 2003 - page 374
- Table 217: Referral patterns of TN patients in Germany, 2003 - page 375
- Table 218: Breakdown of TN patients by pain severity according to the physician type treating them in Germany, 2003 - page 375
- Table 219: Importance of key therapeutic endpoints in TN according to physicians in Germany, 2003 - page 377
- Table 220: Top most widely adopted first-line treatments of TN in Germany, 2003 - page 379
- Table 221: Progression of TN patients to second-line therapy in Germany, 2003 - page 380
- Table 222: Top ten most widely adopted second-line treatments of TN in Germany, 2003 - page 380
- Table 223: Progression of TN patients to third-line therapy in Germany, 2003 - page 381
- Table 224: Top ten most widely adopted third-line treatments of TN in Germany, 2003 - page 381
- Table 225: Prevalence of PHN at one month after detection of herpes zoster in Germany, 2003 - page 382
- Table 226: Referral patterns of PHN patients in Germany, 2003 - page 383
- Table 227: Breakdown of PHN patients by pain severity according to the physician type treating them in Germany, 2003 - page 384
- Table 228: Importance of key therapeutic endpoints in PHN according to physicians in Germany, 2003 - page 385
- Table 229: Top ten most widely adopted first-line treatments of PHN in Germany, 2003 - page 387
- Table 230: Progression of PHN patients to second-line therapy in Germany, 2003 - page 388
- Table 231: Top ten most widely adopted second-line treatments of PHN in Germany, 2003 - page 388
- Table 232: Progression of PHN patients to third-line therapy in Germany, 2003 - page 389
- Table 233: Top ten most widely adopted third-line treatments of PHN in Germany, 2003 - page 389
- Table 234: The NLBP patient population in Germany, 2003 - page 391
- Table 235: Referral patterns of NLBP patients in Germany, 2003 - page 391
- Table 236: Breakdown of NLBP patients by pain severity according to the physician type treating them in Germany, 2003 - page 392
- Table 237: Importance of key therapeutic endpoints in NLBP according to physicians in Germany, 2003 - page 394
- Table 238: Top ten first-line treatments of NLBP in Germany, 2003 - page 396
- Table 239: Progression of NLBP patients to second-line therapy in Germany, 2003 - page 396
- Table 240: Top ten most widely adopted second-line treatments of NLBP in Germany, 2003 - page 397
- Table 241: Progression of NLBP patients to third-line therapy in Germany, 2003 - page 397
- Table 242: Top ten most widely adopted third-line treatments of NLBP in Germany, 2003 - page 398
- Table 243: The fibromyalgia patient population in Germany, 2003 - page 398
- Table 244: Referral patterns of fibromyalgia patients in Germany, 2003 - page 399
- Table 245: Breakdown of fibromyalgia patients by severity according to the physician type treating them in Germany, 2003 - page 400
- Table 246: Importance of key therapeutic endpoints in fibromyalgia according to physicians in Germany, 2003 - page 401
- Table 247: Top first-line treatments of fibromyalgia in Germany, 2003 - page 404
- Table 248: Progression of fibromyalgia patients to second-line therapy in Germany, 2003 - page 405
- Table 249: Top ten most widely adopted second-line treatments of fibromyalgia in Germany, 2003 - page 406
- Table 250: Progression of fibromyalgia patients to third-line therapy in Germany, 2003 - page 407
- Table 251: Top ten most widely adopted third-line treatments of fibromyalgia in Germany, 2003 - page 408
- Table 252: The HIVNP patient population in Germany, 2004 - page 408
- Table 253: Referral patterns of HIVNP patients in Germany, 2003 - page 409
- Table 254: Breakdown of HIVNP patients by pain severity according to the physician type treating them in Germany, 2003 - page 409
- Table 255: Importance of key therapeutic endpoints in HIVNP according to physicians in Germany, 2003 - page 411
- Table 256: Top ten first-line treatments of HIVNP in Germany, 2003 - page 412
- Table 257: Progression of HIVNP patients to second-line therapy in Germany, 2003 - page 413
- Table 258: Top ten most widely adopted second-line treatments of HIVNP in Germany, 2003 - page 414
- Table 259: Progression of HIVNP patients to third-line therapy in Germany, 2003 - page 414
- Table 260: Top ten most widely adopted third-line treatments of HIVNP in Germany, 2003 - page 415
- Table 261: Influence of efficacy attributes on drug choice for neuropathic pain in Germany, 2003 - page 416
- Table 262: Influence of non-symptom therapy impacts on drug choice for neuropathic pain in Germany, 2003 - page 417
- Table 263: Importance of broader drug attributes on therapy choice for neuropathic pain in Germany, 2003 - page 418
- Table 264: Top ten drug combinations for neuropathic pain in Germany, 2003 - page 422
- Table 265: Physician awareness of neuropathic drugs in development in Germany, 2003 - page 423
- Table 266: Influence of clinical trial design on drug choice in Germany, 2003 - page 426
- Table 267: Specific indications versus specific symptoms of neuropathic pain for drug trials in Germany, 2003 - page 427
- Table 268: Six major unmet needs in the treatment of neuropathic pain as identified and ranked by physicians in Germany, 2003 - page 428
- Table 269: How physicians get information for neuropathic pain in Germany, 2003 - page 431
- Table 270: Sample details for the neuropathic pain survey in Italy, 2003 - page 434
- Table 271: Breakdown of neuropathic pain subtypes in Italy - page 436
- Table 272: The DNP patient population in Italy, 2003 - page 437
- Table 273: Referral patterns of DNP patients in Italy, 2003 - page 438
- Table 274: Breakdown of DNP patients by pain severity according to the physician type treating them in Italy, 2003 - page 438
- Table 275: Importance of key therapeutic endpoints in DNP according to physicians in Italy, 2003 - page 439
- Table 276: Top ten most widely adopted first-line treatments of DNP in Italy, 2003 - page 442
- Table 277: Progression of DNP patients to second-line therapy in Italy, 2003 - page 443
- Table 278: Top ten most widely adopted second-line treatments of DNP in Italy, 2003 - page 443
- Table 279: Progression of DNP patients to third-line therapy in Italy, 2003 - page 444
- Table 280: Top ten most widely adopted third-line treatments of DNP in Italy, 2003 - page 444
- Table 281: The TN patient population in Italy, 2003 - page 445
- Table 282: Referral patterns of TN patients in Italy, 2003 - page 445
- Table 283: Breakdown of TN patients by pain severity according to the physician type treating them in Italy, 2003 - page 446
- Table 284: Importance of key therapeutic endpoints in TN according to physicians in Italy, 2003 - page 447
- Table 285: Top most widely adopted first-line treatments of TN in Italy, 2003 - page 449
- Table 286: Progression of TN patients to second-line therapy in Italy, 2003 - page 450
- Table 287: Top ten most widely adopted second-line treatments of TN in Italy, 2003 - page 450
- Table 288: Progression of TN patients to third-line therapy in Italy, 2003 - page 451
- Table 289: Top ten most widely adopted third-line treatments of TN in Italy, 2003 - page 451
- Table 290: Prevalence of PHN at one month after detection of herpes zoster in Italy, 2003 - page 452
- Table 291: Referral patterns of PHN patients in Italy, 2003 - page 452
- Table 292: Breakdown of PHN patients by pain severity according to the physician type treating them in Italy, 2003 - page 453
- Table 293: Importance of key therapeutic endpoints in PHN according to physicians in Italy, 2003 - page 454
- Table 294: Top ten most widely adopted first-line treatments of PHN in Italy, 2003 - page 457
- Table 295: Progression of PHN patients to second-line therapy in Italy, 2003 - page 458
- Table 296: Top ten most widely adopted second-line treatments of PHN in Italy, 2003 - page 458
- Table 297: Progression of PHN patients to third-line therapy in Italy, 2003 - page 459
- Table 298: Top ten most widely adopted third-line treatments of PHN in Italy, 2003 - page 459
- Table 299: The NLBP patient population in Italy, 2003 - page 460
- Table 300: Referral patterns of NLBP patients in Italy, 2003 - page 460
- Table 301: Breakdown of NLBP patients by pain severity according to the physician type treating them in Italy, 2003 - page 461
- Table 302: Importance of key therapeutic endpoints in NLBP according to physicians in Italy, 2003 - page 462
- Table 303: Top ten first-line treatments of NLBP in Italy, 2003 - page 464
- Table 304: Progression of NLBP patients to second-line therapy in Italy, 2003 - page 464
- Table 305: Top ten most widely adopted second-line treatments of NLBP in Italy, 2003 - page 465
- Table 306: Progression of NLBP patients to third-line therapy in Italy, 2003 - page 465
- Table 307: Top ten most widely adopted third-line treatments of NLBP in Italy, 2003 - page 466
- Table 308: The fibromyalgia patient population in Italy, 2003 - page 466
- Table 309: Referral patterns of fibromyalgia patients in Italy, 2003 - page 467
- Table 310: Breakdown of fibromyalgia patients by severity according to the physician type treating them in Italy, 2003 - page 468
- Table 311: Importance of key therapeutic endpoints in fibromyalgia according to physicians in Italy, 2003 - page 469
- Table 312: Top ten first-line treatments of fibromyalgia in Italy, 2003 - page 472
- Table 313: Progression of fibromyalgia patients to second-line therapy in Italy, 2003 - page 473
- Table 314: Top ten most widely adopted second-line treatments of fibromyalgia in Italy, 2003 - page 473
- Table 315: Progression of fibromyalgia patients to third-line therapy in Italy, 2003 - page 474
- Table 316: Top ten most widely adopted third-line treatments of fibromyalgia in Italy, 2003 - page 475
- Table 317: The HIVNP patient population in Italy, 2004 - page 475
- Table 318: Referral patterns of HIVNP patients in Italy, 2003 - page 476
- Table 319: Breakdown of HIVNP patients by pain severity according to the physician type treating them in Italy, 2003 - page 476
- Table 320: Importance of key therapeutic endpoints in HIVNP according to physicians in Italy, 2003 - page 477
- Table 321: Top first-line treatments of HIVNP in Italy, 2003 - page 480
- Table 322: Progression of HIVNP patients to second-line therapy in Italy, 2003 - page 480
- Table 323: Top ten most widely adopted second-line treatments of HIVNP in Italy, 2003 - page 481
- Table 324: Progression of HIVNP patients to third-line therapy in Italy, 2003 - page 481
- Table 325: Top ten most widely adopted third-line treatments of HIVNP in Italy, 2003 - page 482
- Table 326: Influence of efficacy attributes on drug choice for neuropathic pain in Italy, 2003 - page 482
- Table 327: Influence of non-symptom therapy impacts on drug choice for neuropathic pain in Italy, 2003 - page 484
- Table 328: Importance of broader drug attributes on therapy choice for neuropathic pain in Italy, 2003 - page 485
- Table 329: Top ten drug combinations for neuropathic pain in Italy, 2003 - page 489
- Table 330: Physician awareness of neuropathic drugs in development in Italy, 2003 - page 490
- Table 331: Influence of clinical trial design on drug choice in Italy, 2003 - page 492
- Table 332: Specific indications versus specific symptoms of neuropathic pain for drug trials in Italy, 2003 - page 494
- Table 333: Six major unmet needs in the treatment of neuropathic pain as identified and ranked by physicians in Italy, 2003 - page 495
- Table 334: How physicians get information for neuropathic pain in Italy, 2003 - page 498
- Table 335: Sample details for the neuropathic pain survey in Spain, 2003 - page 501
- Table 336: Breakdown of neuropathic pain subtypes in Spain, 2003 - page 503
- Table 337: The DNP patient population in Spain, 2003 - page 504
- Table 338: Referral patterns of DNP patients in Spain, 2003 - p
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