Insomnia - Wake-Up Call for a Sleepy Market
Scope
Report Highlights
Reasons to Purchase
Table of Contents
- ABOUT DATAMONITOR HEALTHCARE - page 2
- About the CNS pharmaceutical analysis team - page 2
- EXECUTIVE SUMMARY - page 5
- Introduction - page 5
- Scope and coverage of the Brief - page 5
- Key findings about the topic - page 6
- Datamonitor estimates that approximately 67 million insomnia patients will receive prescribed drug therapy in 2004 across the seven major markets, although the potential patient population is considerably higher at 238 million across the seven major markets. - page 6
- Ambien is currently the market-leading insomnia drug, with a 94% share of the branded insomnia market. However, the drug will face increasing competition with the launch of generic zolpidem and numerous novel drugs. - page 7
- Sepracor's Estorra and Neurocrine/Pfizer's indiplon are expected to reach market during 2005, and will drive the growth of the insomnia market, both reaching blockbuster status within the forecast period. - page 8
- DISEASE OVERVIEW - page 9
- Disease definition - page 9
- Insomnia classification - page 10
- Epidemiology - page 11
- Prevalence of insomnia - page 11
- Gender - page 12
- Diagnosis and diagnosis rates - page 12
- Treatment - page 14
- Prevalence of insomnia - page 11
- Economic consequences - page 15
- Summary of patient potential - page 16
- Disease definition - page 9
- PHARMACOLOGICAL THERAPY - page 18
- Benzodiazepines - page 18
- Drugs used off-label - page 20
- Antihistamines - page 20
- Antidepressants - page 21
- Unmet needs in insomnia - page 22
- BRANDED INSOMNIA DRUGS - page 24
- Ambien/Stilnox (zolpidem) - page 24
- Marketing strategies - page 25
- Reformulation - page 25
- Demonstrate long-term efficacy and safety of Ambien - page 26
- Sanofi-Aventis and insomnia - page 26
- Marketing strategies - page 25
- Sonata (zaleplon) - page 27
- Marketing strategies - page 28
- Current market overview - page 29
- US market - page 29
- Japanese market - page 30
- European market - page 31
- Ambien/Stilnox (zolpidem) - page 24
- PIPELINE COMPOUNDS - page 34
- Indiplon - page 34
- Marketing strategies - page 37
- Estorra (eszopiclone) - page 39
- Marketing strategies - page 41
- Estorra versus Indiplon - page 42
- TAK-375 - page 44
- Gaboxadol - page 46
- Indiplon - page 34
- FUTURE PERSPECTIVE - page 49
- Reformulation strategies - page 49
- Sonata - page 50
- Ambien CR - page 51
- Free drug trials - page 51
- Targeting US employers - page 52
- Insomnia market forecast - page 53
- Reformulation strategies - page 49
- APPENDIX - page 56
- Contributing experts - page 56
- Bibliography - page 56
- Websites - page 59
- Research methodology - page 59
- Disclaimer - page 60
- List of Tables
- Table 1: Insomnia patient populations (000s) across the seven major markets, 2004 - page 16
- Table 2: Marketed insomnia drugs' revenues in the US, Japan and five major European markets ($m), 1999-2003 - page 32
- Table 3: Insomnia R&D pipeline, 2004 - page 34
- Table 4: Insomnia market forecast, 2003-12 ($m) - page 55
- List of Figures
- Figure 1: Symptoms of insomnia in the US population - page 9
- Figure 2: Characteristics of the ideal hypnotic drug, 2004 - page 23
- Figure 3: Impact of generic of Zimovane revenues in the five major European markets - page 28
- Figure 4: Revenues of Ambien, Sonata and other marketed insomnia drugs in the US, Japan and five major European markets ($m), 1999-2003 - page 33
- Figure 5: Ambien free trial offer - page 52
- Figure 6: Insomnia market forecast, 2004-12 - page 54
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