Commercial Insight: Top 20 Cancer Therapy Brands - Sales of targeted therapies
Scope
Report Highlights
Reasons to Purchase
Table of Contents
- ABOUT DATAMONITOR HEALTHCARE - page 2
- About the Oncology pharmaceutical analysis team - page 2
- CHAPTER 1 EXECUTIVE SUMMARY - page 3
- Scope of the analysis - page 3
- Datamonitor insight into the cancer market - page 4
- Related reports - page 6
- Upcoming reports - page 6
- CHAPTER 2 MARKET OVERVIEW AND DYNAMICS - page 8
- The Top 20 cancer therapy brands - 2006 - page 8
- The current market situation - page 11
- The Top 20 cancer therapy brands - 2016 - page 14
- Sales by class - page 16
- Molecular targeted therapies set to dominate over the forecast period - page 16
- US - page 17
- Japan - page 19
- France - page 21
- Germany - page 23
- Italy - page 25
- Spain - page 27
- UK - page 29
- 5EU - page 31
- Seven major markets - page 33
- Molecular targeted therapies set to dominate over the forecast period - page 16
- Sales by country - page 35
- Other countries slowly catching up with the lucrative US market - page 35
- Brands by class and mode of action - page 37
- Cytotoxic therapies still make up the majority of the forecasted cancer therapy brands - page 37
- Brands by indication - page 39
- Breast cancer drugs strongly dominate among the forecasted cancer therapy brands - page 39
- Brands by company - page 41
- AstraZeneca and Roche are behind the highest number of forecasted cancer therapy brands - page 41
- Brands by event - page 43
- Avastin set to experience the highest number of different events over the forecast period - page 43
- Brands by compound annual growth rate - page 45
- Molecular targeted therapies are driving the positive CAGR for the forecasted cancer therapy brands - page 45
- CHAPTER 3 MARKET DEFINITION - page 49
- Market definition for this report - page 49
- Cytotoxic therapies - page 50
- L1A - Alkylating agents - page 50
- L1B - Antimetabolites - page 50
- L1C - Vinca alkaloids and other plant-derived products - page 50
- L1D - Antineoplastic antibiotics - page 50
- L1X2 - Platinum compounds - page 51
- Antihormonal therapies - page 51
- L2A3 - Luteinizing hormone-releasing hormone analogs - page 51
- L2B1 - Anti-estrogens - page 51
- L2B2 - Anti-androgens - page 52
- L2B3 - Aromatase inhibitors - page 52
- Molecular targeted therapies - page 52
- L1X3 - Antineoplastic monoclonal antibodies - page 52
- L1X9 - All other antineoplastics - page 53
- Cytotoxic therapies - page 50
- Market definition for this report - page 49
- CHAPTER 4 COUNTRY MARKET ASSESSMENTS - page 54
- Current and future opportunities and threats in the cancer market - page 54
- Global opportunities and threats - page 54
- Opportunities - page 54
- Threats - page 59
- US: opportunities and threats - page 64
- Opportunities - page 64
- Threats - page 66
- Japan: opportunities and threats - page 68
- Opportunities - page 68
- Threats - page 69
- 5EU: opportunities and threats - page 71
- Opportunities - page 71
- Threats - page 73
- France: opportunities and threats - page 75
- Opportunities - page 75
- Threats - page 76
- Germany: opportunities and threats - page 77
- Opportunities - page 77
- Threats - page 78
- Italy: opportunities and threats - page 79
- Opportunities - page 79
- Threats - page 80
- Spain: opportunities and threats - page 82
- Opportunities - page 82
- Threats - page 83
- UK: opportunities and threats - page 84
- Opportunities - page 84
- Threats - page 84
- Global opportunities and threats - page 54
- Summary of environmental issues affecting the cancer market size - page 87
- Current and future opportunities and threats in the cancer market - page 54
- CHAPTER 5 FORECAST ANALYSIS - page 89
- Country-specific assumptions and events - page 89
- Effect of Medicare Modernization Act in the US - page 89
- Biennial price cuts in Japan - page 89
- Generic erosion assumptions - page 89
- Product-specific assumptions and events - page 90
- Cytotoxic therapies - page 90
- Abraxane (ABX-007; Abraxis BioScience/AstraZeneca) - page 90
- Alimta (Pemetrexed; Eli Lilly) - page 92
- Camptosar/Campto (Irinotecan; Pfizer/Yakult/Daiichi) - page 94
- Doxil/Caelyx (Pegylated liposomal doxorubicin; Johnson & Johnson/Schering-Plough) - page 96
- Ellence/Farmorubicin (Epirubicin; Pfizer) - page 98
- Eloxatin (Oxaliplatin; Sanofi-Aventis) - page 100
- Furtulon (Doxifluridine; Roche/Chugai) - page 103
- Gemzar (Gemcitabine; Eli Lilly) - page 104
- Navelbine (Vinorelbine; Pierre Fabre/GlaxoSmithKline) - page 106
- Paraplatin (Carboplatin; Bristol-Myers Squibb) - page 107
- Taxol (Paclitaxel; Bristol-Myers Squibb) - page 108
- Taxotere (Docetaxel; Sanofi-Aventis) - page 110
- Temodar/Temodal (Temozolomide; Schering-Plough) - page 113
- TS-1 (Tegafur, gimeracil & oteracil; Taiho Pharmaceuticals/Sanofi-Aventis) - page 115
- UFT (Tegafur & uracil; Taiho Pharmaceuticals) - page 117
- Xeloda (Capecitabine; Roche) - page 119
- Antihormonal therapies - page 121
- Arimidex (Anastrozole; AstraZeneca) - page 121
- Aromasin (Exemestane; Pfizer) - page 123
- Casodex (Bicalutamide; AstraZeneca) - page 125
- Femara (Letrozole; Novartis) - page 127
- Lupron (Leuprorelin; Takeda/TAP/Abbott/Wyeth) - page 129
- Nolvadex (Tamoxifen; AstraZeneca) - page 130
- Zoladex (Goserelin; AstraZeneca) - page 133
- Molecular targeted therapies - page 134
- Avastin (Bevacizumab; Genentech/Roche) - page 134
- Erbitux (Cetuximab; ImClone/Bristol-Myers Squibb/Merck Serono) - page 137
- Gleevec/Glivec (Imatinib; Novartis) - page 141
- Herceptin (Trastuzumab; Genentech/Roche) - page 144
- Iressa (Gefitinib; AstraZeneca) - page 147
- Nexavar (Sorafenib; Onyx Pharmaceuticals/Bayer Schering) - page 149
- Rituxan/MabThera (Rituximab; Biogen Idec/Genentech/Roche) - page 153
- Sutent (Sunitinib; Pfizer) - page 155
- Tarceva (Erlotinib; OSI Pharmaceuticals/Genentech/Roche) - page 157
- Tykerb (Lapatinib; GlaxoSmithKline) - page 159
- Vectibix (Panitumumab; Amgen) - page 161
- Velcade (Bortezomib; Ortho Biotech/Millennium Pharmaceuticals) - page 165
- Cytotoxic therapies - page 90
- Data definitions, limitations and assumptions - page 167
- Standard units - page 167
- Japanese market data - page 167
- Derivation of sales forecasts and pricing trends - page 167
- Forecasts - page 168
- Forecast methodology - page 168
- Country-specific assumptions and events - page 89
- BIBLIOGRAPHY - page 169
- APPENDIX A - MARKET DATA AND MAJOR BRAND KEY FACTS - page 177
- Cytotoxic therapies market data - page 177
- Antihormonal therapies market data - page 185
- Molecular targeted therapies market data - page 189
- APPENDIX B - MARKET FORECAST DATA - page 195
- US forecasts - page 195
- Japan forecasts - page 197
- France forecasts - page 199
- Germany forecasts - page 201
- Italy forecasts - page 203
- Spain forecasts - page 205
- UK forecasts - page 207
- 5EU forecasts - page 209
- Seven major market forecasts - page 211
- APPENDIX C - page 213
- Report methodology - page 213
- About Datamonitor - page 213
- About Datamonitor Healthcare - page 213
- Disclaimer - page 215
- List of Tables
- Table 1: Top 20 cancer therapy brands in the US, Japan, Germany and France, 2006 - page 9
- Table 2: Top 20 cancer therapy brands in Italy, Spain, the UK, collective 5EU and collective seven major markets, 2006 - page 10
- Table 3: Newly marketed drugs included in the Top 20 cancer therapy brands, 2006-2017 - page 11
- Table 4: Seven major market sales of Top 20 cancer therapy brands by drug class, 2006 - page 11
- Table 5: Molecular targeted therapies included in the Top 20 cancer therapy brands, 2006 - page 12
- Table 6: Cytotoxic therapies included in the Top 20 cancer therapy brands, 2006 - page 13
- Table 7: Antihormonal therapies included in the Top 20 cancer therapy brands, 2006 - page 14
- Table 8: Top 20 cancer therapy brands in the US, Japan, Germany and France, 2016 - page 15
- Table 9: Top 20 cancer therapy brands in Italy, Spain, the UK, collective 5EU and collective seven major markets, 2006 - page 16
- Table 10: Forecasted cancer therapy brands by number of different events, 2007-2016 - page 43
- Table 11: Definition of the cancer market, 2007 - page 49
- Table 12: Abraxane: key facts - page 90
- Table 13: Alimta: key facts - page 92
- Table 14: Camptosar: key facts - page 94
- Table 15: Doxil: key facts - page 96
- Table 16: Ellence: key facts - page 98
- Table 17: Eloxatin: key facts - page 100
- Table 18: Furtulon: key facts - page 103
- Table 19: Gemzar: key facts - page 104
- Table 20: Navelbine: key facts - page 106
- Table 21: Paraplatin: key facts - page 107
- Table 22: Taxol: key facts - page 108
- Table 23: Taxotere: key facts - page 110
- Table 24: Market share of Taxotere, 2005 - page 111
- Table 25: Temodar: key facts - page 113
- Table 26: TS-1: key facts - page 115
- Table 27: UFT: key facts - page 117
- Table 28: Xeloda: key facts - page 119
- Table 29: Arimidex: key facts - page 121
- Table 30: Aromasin: key facts - page 123
- Table 31: Casodex: key facts - page 125
- Table 32: Femara: key facts - page 127
- Table 33: Lupron: key facts - page 129
- Table 34: Nolvadex: key facts - page 130
- Table 35: Zoladex: key facts - page 133
- Table 36: Avastin: key facts - page 134
- Table 37: Erbitux: key facts - page 137
- Table 38: Gleevec: key facts - page 141
- Table 39: Herceptin: key facts - page 144
- Table 40: Iressa: key facts - page 147
- Table 41: Nexavar: key facts - page 149
- Table 42: Rituxan: key facts - page 153
- Table 43: Approved indications for Rituxan in the US and EU, 2006 - page 154
- Table 44: Sutent: key facts - page 155
- Table 45: Tarceva: key facts - page 157
- Table 46: Tykerb: key facts - page 159
- Table 47: Vectibix: key facts - page 161
- Table 48: Velcade: key facts - page 165
- Table 49: Abraxane: key facts - page 177
- Table 50: Alimta: key facts - page 177
- Table 51: Camptosar: key facts - page 178
- Table 52: Doxil: key facts - page 178
- Table 53: Ellence: key facts - page 179
- Table 54: Eloxatin: key facts - page 179
- Table 55: Furtulon: key facts - page 180
- Table 56: Gemzar: key facts - page 180
- Table 57: Navelbine: key facts - page 181
- Table 58: Paraplatin: key facts - page 181
- Table 59: Taxol: key facts - page 182
- Table 60: Taxotere: key facts - page 182
- Table 61: Temodar: key facts - page 183
- Table 62: TS-1: key facts - page 183
- Table 63: UFT: key facts - page 184
- Table 64: Xeloda: key facts - page 184
- Table 65: Arimidex: key facts - page 185
- Table 66: Aromasin: key facts - page 185
- Table 67: Casodex: key facts - page 186
- Table 68: Femara: key facts - page 186
- Table 69: Lupron: key facts - page 187
- Table 70: Nolvadex: key facts - page 187
- Table 71: Zoladex: key facts - page 188
- Table 72: Avastin: key facts - page 189
- Table 73: Erbitux: key facts - page 189
- Table 74: Gleevec: key facts - page 190
- Table 75: Herceptin: key facts - page 190
- Table 76: Iressa: key facts - page 191
- Table 77: Nexavar: key facts - page 191
- Table 78: Rituxan: key facts - page 192
- Table 79: Sutent: key facts - page 192
- Table 80: Tarceva: key facts - page 193
- Table 81: Tykerb: key facts - page 193
- Table 82: Vectibix: key facts - page 194
- Table 83: Velcade: key facts - page 194
- Table 84: US forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 195
- Table 85: US forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 196
- Table 86: Japan forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 197
- Table 87: Japan forecasts for the Top 20 cancer therapy brands($m), 2006-2016 (2 of 2) - page 198
- Table 88: France forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 199
- Table 89: France forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 200
- Table 90: Germany forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 201
- Table 91: Germany forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 202
- Table 92: Italy forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 203
- Table 93: Italy forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 204
- Table 94: Spain forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 205
- Table 95: Spain forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 206
- Table 96: UK forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 207
- Table 97: UK forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 208
- Table 98: 5EU forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 209
- Table 99: 5EU forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 - page 210
- Table 100: Seven major market forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (1 of 2) - page 211
- Table 101: Seven major market forecasts for the Top 20 cancer therapy brands ($m), 2006-2016 (2 of 2) - page 212
- List of Figures
- Figure 1: US Top 20 cancer therapy brand sales by class: 2006 - page 17
- Figure 2: US Top 20 cancer therapy brand sales by class: 2016 - page 18
- Figure 3: Japan Top 20 cancer therapy brand sales by class: 2006 - page 19
- Figure 4: Japan Top 20 cancer therapy brand sales by class: 2016 - page 20
- Figure 5: France Top 20 cancer therapy brand sales by class: 2006 - page 21
- Figure 6: France Top 20 cancer therapy brand sales by class: 2016 - page 22
- Figure 7: Germany Top 20 cancer therapy brand sales by class: 2006 - page 23
- Figure 8: Germany Top 20 cancer therapy brand sales by class: 2016 - page 24
- Figure 9: Italy Top 20 cancer therapy brand sales by class: 2006 - page 25
- Figure 10: Italy Top 20 cancer therapy brand sales by class: 2016 - page 26
- Figure 11: Spain Top 20 cancer therapy brand sales by class: 2006 - page 27
- Figure 12: Spain Top 20 cancer therapy brand sales by class: 2016 - page 28
- Figure 13: UK Top 20 cancer therapy brand sales by class: 2006 - page 29
- Figure 14: UK Top 20 cancer therapy brand sales by class: 2016 - page 30
- Figure 15: 5EU Top 20 cancer therapy brand sales by class: 2006 - page 31
- Figure 16: 5EU Top 20 cancer therapy brand sales by class: 2016 - page 32
- Figure 17: Seven major markets Top 20 cancer therapy brand sales by class: 2006 - page 33
- Figure 18: Seven major markets Top 20 cancer therapy brand sales by class: 2016 - page 34
- Figure 19: Top 20 cancer therapy brand sales by country: 2006 - page 35
- Figure 20: Top 20 cancer therapy brand sales by country: 2016 - page 36
- Figure 21: Forecasted cancer therapy brands by class - page 37
- Figure 22: Forecasted cancer therapy brands by mode of action - page 38
- Figure 23: Forecasted cancer therapy brands by indication - page 40
- Figure 24: Forecasted cancer therapy brands by company - page 42
- Figure 25: Forecasted cancer therapy brands by number of different events, 2007-2016 - page 44
- Figure 26: Forecasted cancer therapy brands by CAGR, 2006-2016 - page 45
- Figure 27: Molecular targeted therapy brands by CAGR, 2006-2016 - page 46
- Figure 28: Cytotoxic therapy brands by CAGR, 2006-2016 - page 47
- Figure 29: Antihormonal therapy brands by CAGR, 2006-2016 - page 48
- Figure 30: Seven market population aged 60 and over, 2000-2050 - page 54
- Figure 31: Forecast incidence of cancer across the seven major pharmaceutical markets, 2001-2015 - page 55
- Figure 32: Global oncology sales ($m), 2002-2011 - page 56
- Figure 33: Summary of global opportunities and threats affecting the cancer market, 2007 - page 87
- Figure 34: Summary of regional opportunities and threats affecting the cancer market, 2007 - page 88
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