Biosimilars: Benchmarking the key players
Scope
Report Highlights
Reasons to Purchase
Table of Contents
- CHAPTER 1 EXECUTIVE SUMMARY - page 4
- Scope of the report - page 4
- Key findings - page 4
- Key definitions - page 5
- CHAPTER 2 REVIEW OF KEY BIOSIMILAR DEVELOPERS' PORTFOLIO AND PIPELINE - page 12
- Introduction - page 12
- Future launches are expected to increase the diversity of the biosimilar market - page 13
- Human growth hormone dominates the therapeutic focus of currently-marketed biosimilars - page 13
- Pipeline biosimilars are targeting an increased number of recombinant protein classes - page 16
- Biosimilar developers are turning to a range of drug delivery and formulation technologies to differentiate their products from competitors - page 18
- Innovative injection devices dominate advanced biosimilar drug delivery - page 19
- Improving biosimilar pharmacodynamics using pegylation-like technologies dominates advanced biosimilar drug reformulation - page 20
- Biosimilar developers deprioritize emerging markets and focus pipeline launches on Western markets to maximize profit - page 22
- CHAPTER 3 COLLABORATION AND M&A TRENDS IN THE BIOSIMILARS MARKET - page 24
- There are a wide range of drivers powering licensing and M&A deals - page 25
- Deals are used extensively in the biosimilars market to enable biosimilars to penetrate new markets - page 27
- Top-12 biosimilar developers use M&A deals over licensing deals to access emerging markets - page 28
- Both M&A deals and licensing deals are used by biosimilar developers to access Western markets - page 29
- The core focus for licensing deals is to source marketed and/or pipeline products - page 29
- Much licensing and M&A activity focuses on improving market access or putting up barriers for competitors - page 30
- Biosimilar manufacturers use licensing deals rather than M&A deals to gain access to reformulation and/or drug delivery technologies - page 30
- Deals can also be used to provide a biosimilar with a larger specialist sales force to remove barriers to entry and improve market access - page 31
- CHAPTER 4 BIOSIMILAR COMPANY PROFILES - page 32
- Key biosimilar companies profiled - page 32
- Leading biosimilar developers - page 33
- Teva (and its subsidiary SICOR) - page 34
- Overview - page 34
- Teva's biosimilar product portfolio and pipeline - page 35
- Teva's alliances - page 36
- Teva's strategy - page 36
- Teva's outlook - page 38
- Sandoz - page 38
- Overview - page 38
- Sandoz's biosimilar product portfolio/pipeline - page 39
- Sandoz's alliances - page 42
- Sandoz's strategy - page 43
- Sandoz's outlook - page 45
- Barr (through acquisition of Pliva) - page 45
- Overview - page 45
- Barr's biosimilar product portfolio/pipeline - page 46
- Barr's alliances - page 47
- Barr's strategy - page 48
- Barr's outlook - page 49
- Stada (through Bioceuticals) - page 50
- Overview - page 50
- Bioceutical's biosimilar product portfolio/pipeline - page 51
- Stada/Bioceuticals's alliances - page 52
- Stada/Bioceuticals's strategy - page 53
- Stada/Bioceuticals's outlook - page 54
- BioPartners - page 55
- Overview - page 55
- BioPartners's biosimilar product portfolio/pipeline - page 55
- BioPartners's alliances - page 58
- BioPartners's strategy - page 59
- BioPartners's outlook - page 60
- BioGeneriX (ratiopharm group) - page 62
- Overview - page 62
- BioGeneriX's biosimilar product portfolio/pipeline - page 63
- BioGenerix's alliances - page 64
- BioGenerix's strategy - page 65
- BioGenerix's outlook - page 66
- Teva (and its subsidiary SICOR) - page 34
- New, smaller biosimilar-focused companies - page 66
- Cangene - page 66
- Overview - page 66
- Cangene's biosimilar product portfolio/pipeline - page 68
- Cangene's alliances - page 70
- Cangene's strategy - page 70
- Cangene's outlook - page 71
- Hospira - page 72
- Overview - page 72
- Hospira's outlook - page 74
- Phage Biotechnology - page 74
- Overview - page 74
- Phage Biotechnology's technology - page 75
- Phage's biosimilar product portfolio/pipeline - page 76
- Phage Biotechnology's alliances - page 78
- Phage Biotechnology's strategy - page 78
- Phage Biotechnology's outlook - page 79
- Dragon Pharmaceutical - page 80
- Overview - page 80
- Dragon Pharmaceutical's biosimilar product portfolio/pipeline - page 81
- Dragon Pharmaceutical's alliances - page 82
- Dragon Pharmaceutical's strategy - page 82
- Dragon Pharmaceutical's outlook - page 83
- Neose Technologies - page 83
- Overview - page 83
- Neose Technologies's product portfolio and pipeline - page 84
- Neose Technologies's alliances - page 85
- Neose Technologies's strategy and outlook - page 86
- GeneMedix - page 86
- Overview - page 86
- GeneMedix's biosimilar product portfolio/pipeline - page 88
- GeneMedix's manufacturing - page 89
- GeneMedix's technology - page 89
- GeneMedix's alliances - page 90
- GeneMedix's strategy - page 91
- GeneMedix's outlook - page 92
- Cangene - page 66
- Emerging market-based biosimilar developers and very early-stage companies - page 92
- Indian biosimilars players - page 92
- Wockhardt - page 94
- Biocon - page 95
- Bharat Biotech - page 97
- Shantha Biotech - page 98
- Dr. Reddy's - page 98
- Cipla - page 99
- Chinese biosimilars players - page 99
- Very early-stage biosimilars companies - page 102
- Microbix Biosystems - page 102
- Aceto - page 102
- CJ Corporation - page 103
- Indian biosimilars players - page 92
- CHAPTER 5 BIBLIOGRAPHY - page 104
- On-line articles and paper references - page 104
- CHAPTER 6 APPENDIX : SUPPORTING DATA - page 109
- Definitions - page 109
- List of Tables
- Table 1: Patent expiries of selected key recombinant proteins - page 15
- Table 2: Western M&A targets tend to be more expensive than deals focusing on acquiring emerging market targets - page 28
- Table 3: Teva's biosimilar product portfolio and pipeline - page 35
- Table 4: Sandoz' biosimilar product portfolio and pipeline - page 40
- Table 5: Pliva's biosimilar product portfolio and pipeline - page 46
- Table 6: Stada acquisitions and divestments, 2005-06 - page 51
- Table 7: Bioceuticals' biosimilar product portfolio and pipeline - page 51
- Table 8: BioPartners' biosimilar product portfolio and pipeline - page 56
- Table 9: BioGeneriX's biosimilar product portfolio and pipeline - page 63
- Table 10: Cangene's biosimilar product portfolio and pipeline - page 68
- Table 11: Dragon Pharmaceutical's biosimilar product portfolio and pipeline - page 81
- Table 12: Superbiosimilar products developed by Neose Technologies - page 84
- Table 13: GeneMedix's biosimilar product portfolio and pipeline - page 88
- Table 14: Biosimilar products already marketed in India - page 94
- Table 15: Marketed products from Chinese biosimilars manufacturers - page 100
- List of Figures
- Figure 1: Launched biosimilars belong to six classes of recombinant proteins - page 13
- Figure 2: At least fourteen classes of recombinant proteins are being targeted by biosimilar pipeline drugs in development by the major biosimilar developers - page 17
- Figure 3: Pegylation accounts for the majority of biosimilar modifications made by developers - page 19
- Figure 4: The majority of currently-marketed biosimilars have launched in emerging markets, although the majority of pipeline biosimilars are targeting Western markets - page 22
- Figure 5: Licensing and collaboration deals are used for different purposes compared to M&A deals - page 25
- Figure 6: The focus for licensing and collaboration deals differs from the focus for entering into M&A deals - page 26
- Figure 7: There are three core deal drivers powering both licensing and collaboration deals, and M&A deals - page 27
- Figure 8: Datamonitor expects the initial market leaders to be those with the greatest financial backing and commercial expertise - page 33
- Figure 9: Phage Biotechnology's biosimilar product portfolio and pipeline - page 76
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