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The asthma treatment market is a $15 billion market, driven by an increasing prevalence and yet without a treatment to cure this debilitating disease. All current drugs treat the symptoms but not the underlying cause. It is currently dominated by GSK with its $5.5 billion blockbuster, Advair/Seretide. However, this combination treatment is about to have its first real competition with Symbicort approved for the US market in July 2006. Combination drugs appear likely to dominate the mid-term forecast period as assessed by visiongain.
Pivotal Period
However, a closer look at the potential for this market sees an approaching pivotal period, which could well see considerable change as well as additional growth. New companies are developing products with novel modes of action. The monoclonal antibodies, for so long heralded as the most significant advance the pharmaceutical industry has developed in a number of years, appear to be ready to fulfill their potential in the asthma market.
Concern
Yet there are concerns. There is currently only one available mAb for asthma treatment – Xolair. It is more expensive than other asthma drugs and is only used for patients who have difficult to control asthma. Yet the standard drug treatments are also under examination. Concern over the overuse of steroid treatments has been compounded by recent revelations of possible safety concerns over the long-term use of beta-2 agonist reliever treatments.
The dominant company in this market is GSK but it may see its position slip as new drug treatments enter the market.
Why you should buy this report:
The asthma treatment market is large and is set to grow further.
Generic competition is already having an impact and will having further impetus after the market-leading drug Advair/Seretide loses patent protection in 2008.
By the end of the forecast period the leading companies will be competing with novel products.
Monoclonal antibodies look set to achieve their potential in a market that has significant unmet needs.
Leading drugs in the principal R&D based company pipelines are assessed.
This report considers the latest financial and anecdotal information to enable the most appropriate choice of strategy for this market.
Table of Contents
1. Executive Summary
1.1 Combination Class Leads the Market for Asthma Treatments
1.2 GSK Dominates the Market
1.3 The Asthma and COPD Treatment Market Has High Potential
1.4 Aims, Scope and Format of the Report
1.5 Research Methodology
2. Introduction
2.1 What is Asthma?
2.1.1 Causes of Asthma
2.1.2 Asthma Triggers
2.2 Asthma Rates Have Exploded in Recent Years
2.2.1 Asthma Mortality
2.2.2 The Economic Cost of Asthma Has Increased
2.3 Explanations for Asthma Prevalence Increase
2.4 Definitions
2.5 Asthma: Drug Treatments
2.5.1 Inhaler is Main Delivery Method for Both Asthma and COPD
2.5.2 Combination Therapeutics
2.5.3 Leukotriene Inhibitors
2.5.4 Corticosteroids
2.5.5 Beta-2 (Adrenoreceptor) Agonists
2.5.6 Mast Cell Stabilisers
2.5.7 Methylxanthines
2.5.8 Monoclonal Antibodies
2.5.9 Off-label drugs, Anticholinergics and Antihistamines
2.6 COPD Has Similar Treatments to Asthma
2.6.1 Symptoms of COPD
2.6.2 Management of COPD
2.6.3 Frequent Exacerbations in Patients with COPD
2.6.4 Improvements in COPD Treatments Expected.
3. The World Market Forecast for Asthma and COPD Treatments (2005-2011)
3.1 Combination Therapies Dominate
3.2 Growth Will lessen Throughout the Forecast Period
3.3 Growth in this Market Is Driven by Epidemiological Factors
3.4 GSK Currently the Leading Company But Will Lose Dominance by 2011
3.5 Warnings Act As Restraints To Market Growth
4. The World Market for Combination Drugs, 2005-2011
4.1 Combination Therapeutics - These Are the Most Effective Treatments Available and Will Continue to Drive the Market
4.2 Loss of Patent Protection for Market Leader Will Shape the Market
4.3 New Dosing Regime May Offer Symbicort Significant Market Advantages
4.4 FDA Warning Will Also Impact Revenues
4.5 Is AstraZeneca Pushing Towards a New Model of Asthma Treatment?
4.6 Other Combination Products
4.7 Summary - Combination Asthma and COPD Treatments
5. The World Market for Leukotriene Inhibitors, 2005-2011
5.1 Singulair Dominates the Leukotriene Inhibitor Class
5.2 Original Leukotriene Inhibitor is from Japan
5.3 Accolate - Will This Be Ignored by AstraZeneca?
5.4 Summary - Leukotriene Inhibitors
6. The World Market for Corticosteroids, 2005-2011
6.1 Pulmicort from AstraZeneca is the Market Leader
6.2 GSK Will Increase its Corticosteroid Market Share With Flovent/Flixotide
6.3 Why Will Pulimicort's Revenue Drop?
6.4 Flovent/Flixotide to Become the New Market Leader
6.5 Azmacort - A Supporting Product for Kos Pharmaceuticals
6.6 Qvar - Becotide for the Japanese Market
6.7 Summary - Corticosteroids
7. The World Market for Beta-2 Agonists, 2005-2011
7.1 Steady Growth For The Principal Reliever Drugs
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