Microarray Markets
A microarray is an arrangement of miniaturized test sites or "spots" on a surface. Each spot is usually no more than 250 micrometers in diameter and contains biological molecules--usually DNA or protein--which act as probes for a test sample applied to the array. The surface may be a glass slide, a plastic plate with wells or a polymer bead. The microarray format allows many tests or experiments to be performed simultaneously, in parallel, leading to the generation of huge amounts of biological information for the application of only a tiny amount of sample. Microarrays are often also known as "biochips".
The purpose of this report is to describe the specific segment of the microarray market aimed at analysis of proteins and DNA. Protein microarray applications include:
1) expression profiling
2) serum-based diagnostics
3) protein-protein binding assays
4) drug-target binding
5) receptor epitope binding.
The report examines the market for DNA and protein array testing equipment and supplies using screening reagents and instruments for analysis of individual components in blood, serum or plasma. It defines the dollar volume of sales, both worldwide and in the U.S., and analyzes the factors that influence the size and the growth of the market segments.
Also examined are the subsections of each market segment, including the research labs, hospital labs, and commercial laboratories. Additionally, the numbers of institutions using this type of testing and the factors that influence purchases are discussed.
The report surveys almost all of the companies known to be marketing, manufacturing or developing instruments and reagents for the protein array market in the U.S. Each company is discussed in depth with a section on its history, product line, business and marketing analysis, and a subjective commentary of the company\'s market position.
The five main objectives of this analysis are:
- Identifying viable technology drivers through a comprehensive look at platform technologies for DNA and protein arrays, including, probe-based nucleic acid assays, microarrays and sequencing
- Obtaining a complete understanding of the chief DNA and protein array tests from their basic principles to their applications
- Discovering feasible market opportunities by identifying high-growth applications in different analytical diagnostic areas, focusing on the biggest and expanding markets
- Focusing on global industry development through an in-depth analysis of the major world markets for DNA and protein array technology, including growth forecasts
- Present market figures regarding the current value of the microarray market, projections and growth rates.
The source of this information is the most current data derived from the global diagnostic industry. By purchasing this report, you will have:
- An understanding of the most exciting microarray market segments, current and future.
- The latest information on leading products and research and development (R&D) initiatives.
- Familiarity with recent developments and their effects on selected markets.
- Knowledge of the microarray market as an area of growth, research and investment.
Key questions answered in this report:
- How can microarray tools and technologies facilitate drug discovery, design and development?
- What are the main types of array technologies that are currently available?
- Who are the current key players in this marketplace?
- Which microarray market areas have the greatest potential for growth?
- What is the current state of the microarray market?
- Which biotechnology and pharmaceutical companies are investing in microarray solutions?
- What are the main microarray business strategies adopted by leading companies?
- What are the benefits of microarray technology platforms?
This report contains:
- Detailed analysis of recent trends in the microarray marketplace.
- In-depth profiles of 16 leading companies with microarray tools and technologies.
- A five-year forecast for the microarray market in the biotechnology and pharmaceutical industries.
- Views and principles on the microarray industry from leading industry experts.
- Analysis of potential microarray applications in the life science sector.
- Market predictions and trends analysis concerning U.S. expenditure on array solutions.
- Projections for future applications of microarrays in drug discovery, from the industry\'s R&D perspective.
- Analysis of commercial microarray business strategies.
- The latest news and developments in the microarray marketplace
- A comprehensive overview and insight into microarray business strategies.
Table of Contents
- 1.Overview4
- 1.1Statement of Report4
- 1.2About This Report4
- 1.3Scope of the Report5
- 1.4Objectives6
- 1.5Methodology6
- 1.6Executive Summary7
- 2.Overview of Microarrays9
- 2.1History of Microarrays10
- 2.2Genomics and Proteomics11
- 2.2.1Genetic Variability and Disease12
- 2.3General Theory of Microarrays12
- 2.4DNA Microarrays14
- 2.5Protein Microarrays16
- 2.6Tissue Microarrays17
- 3.DNA Microarrays19
- 3.1Advantages and Drivers19
- 3.2Limitations and Barriers to Commercialization20
- 3.3DNA Microarray Technology Platforms21
- 3.3.1Reasons Why Researchers Utilize DNA Microarrays25
- 3.3.2Factors for Difficulties Applying DNA Microarrays Technology25
- 3.4Key Attributes of DNA Microarray Software26
- 3.5Applications26
- 3.6Future Directions for DNA Microarray Technology31
- 3.6.1High-Throughput Array Technology32
- 3.6.2Emerging Microarray Trends34
- 3.6.3Emerging Microarray Applications34
- 3.6.4Key Points for Developing Microarray Based Applications35
- 3.7Competitive Landscape for DNA Microarrays35
- 4.Protein Microarrays36
- 4.1Critical Factors for Microarray Content36
- 4.2Key Findings on Use of Microarrays36
- 4.3Advantages and Drivers37
- 4.4Limitations and Barriers to Commercialization39
- 4.5Key Experimental Parameters of Protein Microarray Technology for Current and Future Users41
- 4.6Reasons Why Researchers Utilize Protein Microarrays42
- 4.7Factors for Adoption of Protein Microarrays Technology42
- 4.8Top Suppliers of Protein Microarray Slides and Products43
- 4.9Factors that Influence Sale Decisions43
- 4.10Future Innovations in Protein Microarray Technology43
- 5.Current DNA Microarrays44
- 5.1Key Players44
- 5.2.1Microarray-Based Commercial Genotyping Activity46
- 5.2.2Location Analysis46
- 5.3Future Innovations in DNA Microarray Technology47
- 5.1Key Players44
- 6.Current Protein Microarrays48
- 6.1Protein Profiling Microarrays-Antibody Arrays48
- 6.2Protein Profiling Microarrays-Reverse Phase Microarrays50
- 6.3Multiplex Sandwich Microarrays-Planar51
- 6.4Multiplex Sandwich Immunoassays-Bead Based54
- 6.5Microarrays for Protein Function Studies56
- 6.6High Growth Applications58
- 6.6.1Cytokine Arrays58
- 6.6.2Whole Proteome Arrays58
- 6.6.3Microarray-Based Commercial Genotyping Activity59
- 6.6.3.1Microarray-Based Genotyping Applications59
- 6.6.3.2Microbial Applications60
- 6.6.3.3The Market for Microbial Genotyping Products61
- 6.6.3.4Comparative Genomic Hybridization (CGH)61
- 6.6.4ChIP-on-Chip Analysis62
- 7.Technology64
- 7.1Production of Microarrays64
- 7.22-D Versus 3-D Technology66
- 7.3Substrates and Surface Chemistries67
- 7.4Detection Methods69
- 7.5Instruments69
- 7.6Data Management and Informatics in Gene Expression69
- 8.Applications70
- 8.1DNA Microarrays in Gene Expression70
- 8.2DNA Microarrays in SNP Analysis73
- 8.3DNA Microarrays in Cancer74
- 8.4Protein Expression74
- 8.4.1Cytokine Applications75
- 8.4.2Protein Function75
- 8.4.3Protein-Protein Interactions76
- 8.5Target /Biomarker Discovery76
- 8.6Drug Discovery and Development (Gene and Protein Microarrays)77
- 8.7Clinical Diagnostics (Gene and Protein Microarrays)77
- 8.8RNA Microarrays78
- 8.9Oligo Microarrays79
- 8.10Yeast Microarrays79
- 8.11Antibody Arrays79
- 8.12 Arrays for Toxicogenomics80
- 9.The Commercial Opportunity for Microarrays81
- 9.1Market Drivers for Microarrays81
- 9.2Market Restraints for Microarrays81
- 9.3Key Players82
- 9.4Market Size, Strategic Trends and Competitive Landscape for Protein Arrays84
- 9.5Marketing and Distribution86
- 9.6Protein Arrays Market Analysis87
- 9.7Genes Associated with Major Diseases88
- 9.8Software and Data Analysis88
- 9.8.1Supplier of DNA Microarray Analysis Software89
- 9.8.2Satisfaction with Software Features89
- 9.8.3Satisfaction with Software89
- 9.8.4Supplier Factors in Software Purchase Decision89
- 9.8.5Suppliers\' Role in Improving Data Sharing for DNA Microarrays89
- 10.Company Profiles90
- 10.1Manufacturers127
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