Microarray Markets
A microarray is an arrangement of miniaturized test sites or "spots" on a surface. Each spot is usually no more than 250 micrometers in diameter and contains biological molecules--usually DNA or protein--which act as probes for a test sample applied to the array. The surface may be a glass slide, a plastic plate with wells or a polymer bead. The microarray format allows many tests or experiments to be performed simultaneously, in parallel, leading to the generation of huge amounts of biological information for the application of only a tiny amount of sample. Microarrays are often also known as "biochips". The purpose of this TriMark Publications report is to describe the specific segment of the microarray market aimed at analysis of proteins and DNA. Protein microarray applications include:
1) expression profiling;
2) serum-based diagnostics;
3) protein-protein binding assays;
4) drug-target binding; and
5) receptor epitope binding.
It examines the market for DNA and protein array testing equipment and supplies using screening reagents and instruments for analysis of individual components in blood, serum or plasma. It defines the dollar volume of sales, both worldwide and in the U.S., and analyzes the factors that influence the size and the growth of the market segments. Also examined are the subsections of each market segment, including the research labs, hospital labs, and commercial laboratories. Additionally, the numbers of institutions using this type of testing and the factors that influence purchases are discussed. The report surveys almost all of the companies known to be marketing, manufacturing or developing instruments and reagents for the protein array market in the U.S. Each company is discussed in depth with a section on its history, product line, business and marketing analysis, and a subjective commentary of the company's market position.
The five main objectives of this analysis are:
- Identifying viable technology drivers through a comprehensive look at platform technologies for DNA and protein arrays, including, probe-based nucleic acid assays, microarrays and sequencing.
- Obtaining a complete understanding of the chief DNA and protein array tests from their basic principles to their applications
- Discovering feasible market opportunities by identifying high-growth applications in different analytical diagnostic areas, focusing on the biggest and expanding markets
- Focusing on global industry development through an in-depth analysis of the major world markets for DNA and protein array technology, including growth forecasts
- Present market figures regarding the current value of the microarray market, projections and growth rates.
The source of this information is the most current data derived from the global diagnostic industry.
By purchasing this report, you will have:
- An understanding of the most exciting microarray market segments, current and future
- The latest information on leading products and research and development (R&D) initiatives
- Familiarity with recent developments and their effects on selected markets
- Knowledge of the microarray market as an area of growth, research and investment.
Key questions answered in this report:
- How can microarray tools and technologies facilitate drug discovery, design and development?
- What are the main types of array technologies that are currently available?
- Who are the current key players in this marketplace?
- Which microarray market areas have the greatest potential for growth?
- What is the current state of the microarray market?
- Which biotechnology and pharmaceutical companies are investing in microarray solutions?
- What are the main microarray business strategies adopted by leading companies?
- What are the benefits of microarray technology platforms?
This report contains:
- Detailed analysis of recent trends in the microarray marketplace
- In-depth profiles of 16 leading companies with microarray tools and technologies
- A five-year forecast for the microarray market in the biotechnology and pharmaceutical industries
- Views and principles on the microarray industry from leading industry experts
- Analysis of potential microarray applications in the life science sector
- Market predictions and trends analysis concerning U.S. expenditure on array solutions
- Projections for future applications of microarrays in drug discovery, from the industry's R&D perspective
- Analysis of commercial microarray business strategies
- The latest news and developments in the microarray marketplace
- A comprehensive overview and insight into microarray business strategies.
Table of Contents
- 1.Overview4
- 1.1Statement of Report4
- 1.2About This Report4
- 1.3Scope of the Report5
- 1.4Objectives6
- 1.5Methodology6
- 1.6Executive Summary7
- 2.Overview of Microarrays9
- 2.1History of Microarrays9
- 2.2Genomics and Proteomics10
- 2.2.1Genetic Variability and Disease11
- 2.3General Theory of Microarrays11
- 2.4DNA Microarrays12
- 2.5Protein Microarrays14
- 2.6Tissue Microarrays15
- 3.DNA Microarrays17
- 3.1Advantages and Drivers17
- 3.2Limitations and Barriers to Commercialization18
- 3.3DNA Microarray Technology Platforms19
- 3.3.1Reasons Why Researchers Utilize DNA Microarrays23
- 3.3.2Factors for Difficulties Applying DNA Microarrays Technology23
- 3.4Key Attributes of DNA Microarray Software24
- 3.5Applications24
- 3.6Future Directions for DNA Microarray Technology29
- 3.6.1High-Throughput Array Technology29
- 3.6.2Emerging Microarray Trends31
- 3.6.3Emerging Microarray Applications31
- 3.6.4Key Points for Developing Microarray Based Applications32
- 4.Protein Microarrays33
- 4.1Critical Factors for Microarray Content33
- 4.2Key Findings on Use of Microarrays33
- 4.3Advantages and Drivers34
- 4.4Limitations and Barriers to Commercialization36
- 4.5Key Experimental Parameters of Protein Microarray Technology for Current and Future Users38
- 4.6Reasons Why Researchers Utilize Protein Microarrays39
- 4.7Factors for Adoption of Protein Microarrays Technology39
- 4.8Top Suppliers of Protein Microarray Slides and Products40
- 4.9Factors that Influence Sale Decisions40
- 4.10Future Innovations in Protein Microarray Technology40
- 5.Current DNA Microarrays41
- 5.1Key Players41
- 5.2High Growth Applications43
- 5.2.1Microarray-Based Commercial Genotyping Activity43
- 5.2.2Location Analysis43
- 5.3Future Innovations in DNA Microarray Technology43
- 6.Current Protein Microarrays45
- 6.1Protein Profiling Microarrays-Antibody Arrays45
- 6.2Protein Profiling Microarrays-Reverse Phase Microarrays47
- 6.3Multiplex Sandwich Microarrays-Planar48
- 6.4Multiplex Sandwich Immunoassays-Bead Based50
- 6.5Microarrays for Protein Function Studies52
- 6.6High Growth Applications54
- 6.6.1Cytokine Arrays54
- 6.6.2Whole Proteome Arrays54
- 6.6.3Microarray-Based Commercial Genotyping Activity54
- 6.6.3.1Microarray-Based Genotyping Applications54
- 6.6.3.2Microbial Applications55
- 6.6.3.3The Market for Microbial Genotyping Products56
- 6.6.3.4Comparative Genomic Hybridization56
- 6.6.4ChIP-on-Chip Analysis57
- 7.Technology59
- 7.1Production of Microarrays59
- 7.22-D Versus 3-D Technology61
- 7.3Substrates and Surface Chemistries61
- 7.4Detection Methods63
- 7.5Instruments63
- 7.6Data Management and Informatics in Gene Expression64
- 8.Applications65
- 8.1DNA Microarrays in Gene Expression65
- 8.2DNA Microarrays in SNP Analysis68
- 8.3DNA Microarrays in Cancer69
- 8.4Protein Expression69
- 8.4.1Cytokine Applications70
- 8.4.2Protein Function70
- 8.4.3Protein-Protein Interactions71
- 8.5Target /Biomarker Discovery71
- 8.6Drug Discovery and Development (Gene and Protein Microarrays)72
- 8.7Clinical Diagnostics (Gene and Protein Microarrays)72
- 8.8RNA Microarrays73
- 8.9Oligo Microarrays73
- 8.10Yeast Microarrays74
- 8.11Antibody Arrays74
- 9.The Commercial Opportunity for Microarrays75
- 9.1Market Drivers for Microarrays75
- 9.2Market Restraints for Microarrays75
- 9.3Key Players76
- 9.4Market Size, Strategic Trends and Competitive Landscape for Protein Arrays79
- 9.5Marketing and Distribution81
- 9.6Protein Arrays Market Analysis82
- 9.7Genes Associated with Major Diseases83
- 9.8Software and Data Analysis83
- 9.8.1Supplier of DNA Microarray Analysis Software84
- 9.8.2Satisfaction with Software Features84
- 9.8.3Satisfaction with Software84
- 9.8.4Supplier Factors in Software Purchase Decision84
- 9.8.5Suppliers' Role in Improving Data Sharing for DNA Microarrays84
- 10.Legal Aspects of Commercialization of Protein Arrays85
- 11.Company Profiles87
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