Disposable Syringe Markets
This report examines the disposable syringe markets as well as the supplies utilized in clinics and by patients directly in their homes to diagnose and monitor disease and to administer medications. This analysis is intended to provide basic market data pertaining to the U.S. and worldwide market segments. Each market segment is analyzed to determine size, growth rates, sales projections and factors influencing growth in the U.S. and internationally. Unit and dollar volume are used to indicate market sizes.
Additionally, this review examines industry challenges and potential threats to syringe and needle supplies manufacturers and makes strategic recommendations for boosting market share. The emphasis is on those companies actively developing and marketing products to hospitals, physicians and the general public for medically related uses.
The disposable syringe market segments are identified as:
1) total reusable needle and syringe market;
2) total disposable needle and syringe market;
3) prefilled syringes;
4) safety syringes;
5) insulin injector pens;
6) needleless injectors;
7) vaccination injectors;
8) blood collection needles and syringes;
9) hypodermic needles and syringes market;
10) insulin needles and syringes market;
11) specialty needles and syringes market;
12) needleless injector market.
Table of Contents
TABLE OF CONTENTS
1. Introduction 11
- 1.1 Statement of Report 11
- 1.2 About this Report 11
- 1.3 Scope of the Report 11
- 1.4 Objectives 12
- 1.5 Methodology 13
- 1.6 Executive Summary 14
2. Disposable Syringe Markets 16
- 2.1 Overview 16
- 2.2 Infection Control and Safety 17
- 2.2.1 Needlestick Injuries 17
- 2.2.2 Availability of Safety Syringes in the U.S. Healthcare Facilities 19
- 2.3 Cost of Safety Syringe 19
- 2.4 Market Expansion 20
- 2.5 Unsafe Injection Practices 20
- 2.6 Hospital Consolidations Pressure Companies to Reduce Prices 20
- 2.7 Strategic Alliance of Needleless Injector Manufacturers 21
- 2.8 Technological Advancements in Disposable Syringes 21
- 2.8.1 Reconstitution inside Sterile Syringes 21
- 2.8.2 Plungerless Prefilled Syringes 22
- 2.8.3 The Disposable UniJect™ 22
- 2.9 Award Winning Syringes 22
- 2.9.1 Episure AutoDetect Epidural Syringe 23
- 2.9.2 ConfiDose Disposable Autoinjector 23
- 2.9.3 Humatrope Reconstitution Device 24
- 2.9.4 Vasceze Plungerless Syringe 24
3. Disposable Syringe Market Segments 25
- 3.1 Overview 25
- 3.1.1 World Market for Disposable Syringes 25
- 3.1.2 U.S. Market for Disposable Syringes 27
- 3.1.3 Disposable Syringe Market in India 29
4. Insulin Syringes 32
- 4.1 Insulin Strengths: U-40 and U-100 32
- 4.2 Market for Insulin Pen 33
- 4.3 Shelf Life of Insulin Pen Cartridges 34
- 4.4 An Update on Insulin Injection Devices 35
- 4.4.1 Insulin Injection Devices Currently Available in the U.S. 35
- 4.4.2 Disposable Pens 36
- 4.4.3 Refillable Pens 36
- 4.4.4 Pen Needles 36
- 4.4.5 Benefits and Patient Preferences 37
- 4.4.6 Disadvantages of Pen Syringes 37
- 4.4.7 Insulin Pens and the Hospital Bills 38
- 4.5 Insulin Pens for Indian Market from IDC 38
- 4.6 Expansion of Facilities for Insulin Pens by Eli Lilly and Rexam 39
- 4.7 Major Players in Insulin Pens and Syringes 39
- 4.7.1 Sanofi-Aventis 39
- 4.7.1.1 Sanofi-Aventis’ Business in Diabetes Care Segment 39
- 4.7.2 Novo Nordisk 41
- 4.7.2.1 Novo Nordisk’s Diabetes Care Business in North America 41
- 4.7.2.2 Novo Nordisk’s International Operations 42
- 4.7.2.3 Novo Nordisk’s Business in Diabetes Care in Europe 42
- 4.7.3 Eli Lilly & Co. 43
- 4.7.3.1 Byetta 43
- 4.7.3.2 Humulin 44
- 4.7.3.3 Humalog 45
- 4.7.1 Sanofi-Aventis 39
5. Safety Syringes 46
- 5.1 Available Safety Syringe Technologies 46
- 5.1.1 Retrofitted Syringes 46
- 5.1.2 Automatically Retractable Syringes 46
- 5.1.3 Manually Retractable Syringes 46
- 5.2 Safety Syringe Market 47
- 5.3 Drivers of Safety Syringes 47
6. Prefilled Syringes 48
- 6.1 Types of Prefilled Syringes (PFS) 48
- 6.2 Market for Prefilled Syringes 48
- 6.3 The Rise of Prefilled Syringes 49
- 6.4 Needle Safety for Prefilled Syringes 50
- 6.4.1 V-OVS NS® 51
- 6.4.2 Preventis™ 51
- 6.4.3 UltraSafe Passive® Delivery System/ERYPROSafe™ and NUFILSafe™ 51
- 6.5 Sterility Maintenance of Prefilled Syringes 52
- 6.6 Compatibility of Drugs with the Components of Prefilled Syringes 52
- 6.7 Some of the Drugs Available in Prefilled Syringes 53
- 6.7.1 Ovidrel® PreFilled Syringe 53
- 6.7.2 Enbrel Prefilled Syringes 53
- 6.7.3 Biocon’s Prefilled Safety Syringes 53
- 6.7.4 Relistor® Prefilled Syringes 54
- 6.7.5 PEGASYS® 54
- 6.7.6 Afluria® 54
- 6.7.7 Enzira® 55
- 6.7.8 FluZone® Prefilled Syringe for Children 55
- 6.7.9 Novolin® N FlexPen Prefilled Insulin Syringe 55
- 6.7.10 NovoLog® Insulin Prefilled Syringe 55
- 6.7.11 GlaxoSmithKline’s Vaccines in Prefilled Syringes 56
- 6.8 U.S. Production of Unilife’s Prefilled Syringes 56
- 6.9 Some of the Major Providers of Syringe-Prefilling Services and Products 57
- 6.9.1 Althea Technologies, Inc. 57
- 6.9.1.1 Althea’s Clinical Manufacturing 57
- 6.9.1.2 Althea’s Fill/Finish Services 58
- 6.9.1.3 Althea’s Contract Manufacturing 58
- 6.9.2 Baxter International, Inc. 59
- 6.9.2.1 Baxter’s Contract Manufacturing 60
- 6.9.2.2 Baxter’s Fill and Finish Capabilities 60
- 6.9.2.3 Baxter’s Prefilled Syringes Capability 60
- 6.9.2.4 Baxter’s Vials 61
- 6.9.2.5 Baxter’s Cartridges 61
- 6.9.3 Becton, Dickinson and Company 61
- 6.9.3.1 BD’s Prefilled Syringe Services 62
- 6.9.3.2 BD Hypak SCF™ Glass Prefillable Syringes 62
- 6.9.3.3 BD Sterifill SCF™ Plastic Prefillable Syringe Systems 63
- 6.9.3.4 BD Physioject™ Disposable AutoInjector 63
- 6.9.3.5 BD™ MicroInfusor™ Automatic Injection System 64
- 6.9.3.6 BD™ Liquid Dry Injector Disposable Pen Injector 64
- 6.9.3.7 BD™ Pens Customized Self-Injection Systems 65
- 6.9.3.8 BD Soluvia™ Prefillable Microinjection System 65
- 6.9.3.9 BD Preventis™ Shielding System for Prefilled Syringes 66
- 6.9.4 Catalent Pharma Solutions, Inc. 68
- 6.9.4.1 The Protector Safety Shield System™ 69
- 6.9.4.2 The ASI™ Autoinjector and Ultra-Compact ASI Mini™ Autoinjector 69
- 6.9.5 Hyaluron Contract Manufacturing (HCM) 69
- 6.9.5.1 Hyaluron’s Syringe Filling 69
- 6.9.6 Vetter Pharma Fertigung GmbH 70
- 6.9.1 Althea Technologies, Inc. 57
- 6.10 Features of Prefilled Syringes 71
- 6.10.1 Dual Chamber Prefilled Syringes 71
7. Pen Syringes 72
- 7.1 Pen Devices for Insulin Delivery 73
- 7.2 Technical Advances in Insulin Pens 73
- 7.3 Pen Types and Styles 74
- 7.4 Prefilled Pens 74
- 7.5 Reusable Pens 74
- 7.6 Prefilled Autoinjecting Disposable Syringes 74
- 7.7 Uniject™ Injection Device 75
8. Microneedle 76
- 8.1 Electronic Mosquito 76
9. Needle-free Injectors 77
- 9.1 Needle-free Delivery of Liquids 77
- 9.2 Needle-free Delivery of Solid Formulations 78
- 9.3 Needleless Injector from Injex 79
- 9.4 Jet Syringe from Injex 79
- 9.5 Syrijet 79
- 9.6 PenJet 80
- 9.7 Needle-free Injector for Human Growth Hormone 80
10. Needle and Syringe Market Trends 81
- 10.1 Market Segments 81
- 10.2 Customer Needs 82
- 10.3 Competitor Analysis 82
- 10.3.1 Automatic Safety Syringes 82
- 10.3.2 Manually Locking Safety Syringes 83
- 10.4 Third Party Reimbursement 84
- 10.5 Regulation 84
- 10.6 Drug Discovery Trends 85
- 10.7 Demographic Shifts 85
- 10.8 Growth in Home Healthcare 85
11. Technological Developments 87
- 11.1 Auto-Disable Syringes 87
- 11.1.1 AD Syringes with Needle Retraction/Disposal Feature 88
- 11.1.2 AD Syringe with No Needle Retraction Feature 88
- 11.1.3 Needlestick Prevention Syringes 88
- 11.1.4 Automatic Needlestick Prevention Feature 89
- 11.1.4.1 UltraSafe®Passive™ Delivery System 89
- 11.1.4.2 Sterimatic Sleeve® 89
- 11.1.4.3 K3 Safety Cap 89
- 11.2 Manual Needlestick Prevention Feature 90
- 11.2.1 Safety Lok™ Syringe 90
- 11.2.2 Monoject®Magellan™ 90
12. Business Trends 91
- 12.1 Market Drivers 91
- 12.2 Market Prospects 92
- 12.3 Marketing and Distribution 93
- 12.4 Competitive Landscape 93
- 12.5 Future Technologies 94
- 12.5.1 Glide Solid Dose Injector (SDI™) 94
- 12.5.2 BD Physioject™ 94
13. Regulatory Measures 95
- 13.1 Safety Syringes in Europe 95
14. Company Profiles 96
- 14.1 Abbott Laboratories 96
- 14.1.1 HUMIRA® Prefilled Syringe 96
- 14.1.2 HUMIRA® Pen 97
- 14.1.3 Precision Sure-Dose® Insulin Syringes 97
- 14.2 Albert David Limited 98
- 14.3 Alshifa Medical Syringes Manufacturing Company Ltd. 99
- 14.4 Althea Technologies, Inc. 99
- 14.5 Avitro, Inc. 100
- 14.6 Baxter International, Inc. 100
- 14.6.1 Baxter’s Medication Delivery 100
- 14.6.2 Baxter’s IV Therapies 101
- 14.6.3 Baxter’s Global Injectables 101
- 14.6.4 Baxter’s Infusion Systems 102
- 14.6.5 Baxter’s IV Infusion Pumps and Infusion Sets 103
- 14.6.6 Baxter’s Pharma Partnering 103
- 14.7 Becton, Dickinson and Company (BD) 103
- 14.7.1 BD’s Role in Designing Devices for Safe and Effective Injections and Infusions 103
- 14.7.2 BD’s Products 103
- 14.8 Boston Scientific Corporation 113
- 14.9 B. Braun 113
- 14.9.1 The Hospital Care Division 113
- 14.9.2 The Aesculap Division 114
- 14.9.3 The Out Patient Market (OPM) Division 114
- 14.9.4 The B. Braun Avitum Division 115
- 14.9.5 B. Braun’s Syringe Products 116
- 14.10 Bioject Medical Technologies, Inc. 122
- 14.10.1 Biojector® 2000 124
- 14.10.2 Drug Reconstitution System 125
- 14.10.3 Vitajet® 125
- 14.10.4 Cool.click™ 125
- 14.10.5 SeroJet™ 126
- 14.11 Catalent Pharma Solutions, Inc. 126
- 14.11.1 Catalent’s Oral Technologies Segment 127
- 14.11.2 Catalent’s Sterile Technologies Segment 128
- 14.11.3 Catalent’s Packaging Services Segment 129
- 14.11.4 Catalent’s Manufacturing Capabilities 130
- 14.11.5 Catalent’s Employee Strength 130
- 14.11.6 Catalent’s Syringes 131
- 14.12 C.R. Bard, Inc. 131
- 14.12.1 Bard’s Vascular Business 131
- 14.12.2 Bard’s Urology Business 132
- 14.12.3 Bard’s Oncology Business 133
- 14.12.4 Bard’s Business in Surgical Specialties 134
- 14.12.5 Bard’s Overseas Expansion 134
- 14.12.6 Bard’s Bulb Syringes and Trays 135
- 14.12.7 Bard’s Piston Syringes and Trays 135
- 14.13 Coeur, Inc. 136
- 14.13.1 Angiographic Syringes from Coeur, Inc. 136
- 14.13.2 CT Syringes from Coeur, Inc. 137
- 14.14 Covidien Ltd. 137
- 14.14.1 Covidien’s Medical Devices Segment 138
- 14.14.2 Covidien’s R&D 139
- 14.14.3 Covidien’s Competitors in Medical Devices 139
- 14.14.4 Covidien’s Syringes 140
- 14.15 Henke-Sass, Wolf GmbH 144
- 14.15.1 Two-Part Disposable Syringes 1-50(60) ml 144
- 14.15.2 Three-Part Disposable Syringes 1-30 ml 144
- 14.15.3 Disposable Needles HSW FINE-JECT® 145
- 14.16 Hindustan Syringes & Medical Devices, Ltd. (HMD) 145
- 14.16.1 Insulin Syringes from HMD 145
- 14.16.2 HMD’s Single Use Needles 146
- 14.16.3 HMD’s Single Use Syringes 147
- 14.17 Hi-Tech Medical Products Ltd. 147
- 14.18 Hyaluron Contract Manufacturing 148
- 14.18.1 HCM’s Major Markets 148
- 14.18.2 HCM’s Facility 148
- 14.19 International Medication System Ltd. 149
- 14.19.1 Delivery Systems from IMS 149
- 14.19.2 PCA Products from IMS 151
- 14.19.3 Phytonadione Injection USP 151
- 14.19.4 Lidocaine HCl Jelly, USP 2% (Preservative-free) 152
- 14.20 Life-Shield Products, Inc. 152
- 14.21 Merit Medical Systems, Inc. 154
- 14.21.1 Merit’s Products 154
- 14.21.2 Merit’s Vascular Access Products 154
- 14.21.3 Merit’s Business in the U.S. 155
- 14.21.4 Merit’s International Business 156
- 14.21.5 Merit’s Customers 156
- 14.21.6 Merit’s R&D 156
- 14.21.7 Merit’s Manufacturing Facilities 157
- 14.22 Milestone Scientific 157
- 14.22.1 Milestone Scientific’s Product Platform 158
- 14.22.2 Milestone Scientific’s Investment in R&D 159
- 14.22.3 Milestone Scientific’s Business Performance 160
- 14.23 Novo Nordisk A/S 161
- 14.23.1 Novo Nordisk’s Business in Diabetes Care Segment 161
- 14.23.2 Novo Nordisk’s Modern Insulins, Human Insulins and Insulin-related Products 162
- 14.23.3 Novo Nordisk’s Geographic Performance in Diabetes Care Products 163
- 14.23.4 Pipeline Progress in Nova Nordisk 163
- 14.23.5 Novo Nordisk’s Modern Insulin Portfolio 164
- 14.24 Owen Mumford Ltd. 166
- 14.24.1 Owen Mumford’s Global Locations 166
- 14.24.2 Owen Mumford’s Products 168
- 14.25 Plas-Pak Industries, Inc. 170
- 14.25.1 Dial-A-Dose® Disposable Veterinary Syringes 170
- 14.25.2 Dual Syringe and Dental Syringe from Plas-Pak 170
- 14.25.3 Mini Dual Syringe 170
- 14.25.4 Manual Dual Syringes 171
- 14.26 Retractable Technologies, Inc. 172
- 14.26.1 Retractable Technologies’ Principal Products 173
- 14.26.2 Retractable Technologies’ Principal Markets 173
- 14.26.3 Retractable Technologies’ R&D 174
- 14.26.4 Retractable Technologies’ VanishPoint Products 175
- 14.27 Revolutions Medical Corporation 176
- 14.27.1 Rev Vac Safety Syringe 177
- 14.28 Safety Syringes, Inc. 177
- 14.28.1 Custom Engineering from Safety Syringes, Inc. 178
- 14.28.2 Syringe Products from Safety Syringes, Inc. 178
- 14.29 Smiths Medical International/Medex, Inc. 180
- 14.29.1 Smiths Medical’s Markets 180
- 14.29.2 Smiths Medical’s Medication Delivery Segment 181
- 14.29.3 Smiths Medical’s Vital Care Segment 182
- 14.29.4 Smiths Medical’s Safety Devices Segment 182
- 14.29.5 Smiths Medical’s Business Performance 182
- 14.29.6 Smiths Medical’s Business Performance on Geographic Basis 182
- 14.29.7 Smiths Medical’s R&D 183
- 14.29.8 Syringes from Smiths Medicals 183
- 14.30 Specialized Health Products International, Inc. 188
- 14.30.1 SHPI’s Products and Services 189
- 14.30.2 SHPI’s Licensed Products 190
- 14.31 Star Syringe Ltd. 190
- 14.31.1 Star Alliances 191
- 14.31.2 Preoducts from Star Syringe Ltd. 192
- 14.32 Terumo’s Medical Corporation 193
- 14.32.1 Terumo’s General Hospital Products 193
- 14.32.2 Terumo’s Diabetes Care Products 194
- 14.32.3 Terumo’s Syringe Products 195
- 14.33 UltiMed, Inc. 203
- 14.33.1 UltiCare™ Insulin Syringes 204
- 14.33.2 UltiCare™ Pen Needles 204
- 14.34 Unilife Medical Solutions, Ltd. 205
- 14.34.1 Pharmaceutical Market for Unilife’s Prefilled Syringes 205
- 14.34.2 Unilife Partnership with Sanofi-Aventis 205
- 14.34.3 Unilife’s Licensing Agreement with Sanofi-Aventis 206
- 14.34.4 Unilife’s Partnership with Gerresheimer Bünde 206
- 14.34.5 Unilife’s Portfolio of Safety Syringes 207
- 14.34.6 Unilife’s Prefilled Syringes 207
- 14.34.7 Unilife’s Contract Manufacturing Activities 207
- 14.34.8 Unilife’s Performance in Syringe Market 208
- 14.35 Vetter Pharma-Fertigung GmbH & Co., KG 208
- 14.35.1 Vetter Services and Solutions 208
- 14.35.2 Dual-Chamber Technology 209
- 14.36 Vita Needle Company, Inc. 209
- 14.36.1 Disposable Stainless Steel Needle Blunts from Vita Needle 209
- 14.36.2 Teflon® Dispensing Needles 210
- 14.36.3 Vita Needle’s Polypropylene Needles 210
- 14.36.4 Vita Needle’s Taper Tip Needles 211
- 14.37 West Pharmaceutical Services, Inc. 211
- 14.37.1 West’s Pharmaceutical Systems Segment 211
- 14.37.2 West’s Tech Group Segment 212
- 14.37.3 West’s R&D Activities 213
- 14.37.4 West’s Syringe Products 214
- 14.38 Wuxi Yushou Medical Appliances Co., Ltd. 217
- 14.39 Ypsomed Holding AG 217
- 14.39.1 Ypsomed’s Injection Systems 218
- 14.39.2 Ypsomed’s Insulin Delivery Systems 218
- 14.39.3 Additional Indication Areas for Pen Systems 218
- 14.39.4 Ypsomed’s Innovative Injection Systems at a Glance 219
- 14.39.5 Ypsomed’s Complete Product Range for Insulin Suppliers 219
- 14.39.6 Ypsomed’s New Dual-Chamber Injecting Systems 220
- 14.39.7 Ypsomed’s ServoPen 220
- 14.39.8 Growth of Ypsomed’s Pen Needles 220
- 14.39.9 Ypsomed’s Performance in 2008/2009 222
- 14.39.10 Ypsomed’s R&D 223
- 14.40 The Medical House PLC (TMH) 224
- 14.40.1 TMH’s Products 224
Appendix 1: U.S. Healthcare Expenditure Projections, 2008-2018 228
- Appendix 2: Syringe Needle Terminology 234
- Appendix 3: Medication Errors and Syringe Safety 236
- Appendix 3.1: Injectable Medication Errors 236
- Appendix 3.2: Frequency of Syringe Usage 236
- Appendix 3.3: Labeling Injectable Medications 236
- Appendix 3.4: Challenges of Labeling 236
- Appendix 3.5: Benefits of a Write-On Stripe 236
- Appendix 3.6: Nurses Influence on Selection of Sharp Devices 237
- Appendix 3.7: Needlestick Injuries 237
- Appendix 3.8: Prevention of Needlestick Injuries 237
- Appendix 3.9: Protection from Needlestick Injuries 238
INDEX OF FIGURES
- Figure 2.1: Principal Causes of Needlestick Injuries 17
- Figure 2.2: Availability of Safety Syringes in the U.S. Healthcare Facilities, 2008 19
- Figure 3.1: Worldwide Unit Market for Syringes and Needles, 2004-2012 26
- Figure 3.2: Global Syringe Market, 2009 26
- Figure 3.3: Worldwide Market for Disposable Syringes and Needl
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