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Microscopy Markets

This report deals primarily with the analysis of market segments of microscopes used in clinical and research laboratories. Emphasis is on the U.S. markets; however, the worldwide markets are analyzed and discussed as well.

Specifically, this report examines those companies and products which are actively developing and marketing microscopy devices and supplies in market segments which have the potential for growth rates above 5% per year over the next five years. It continues to examine those microscopy devices operated as light, confocal, electron and scanning probe microscopes. Also analyzed are applications for certain microscope technology platforms such as semi-conductor processing systems and automated imaging systems.

Concentration is centered on an overview of individual microscopy markets, which are believed to possess the elements that will lead to sustained growth rates for the foreseeable future. This report assesses the current status of each market, makes projections for market size, discusses the market strategies of leading companies in each market segment, and evaluates the forces that underlie the high growth of each segment. Additionally, there\'s an overview of the instruments and supplies marketed by major companies in each market segment. Analysis of the market size, growth rates, and market components for instruments used for microscopy are also discussed.

Table of Contents

• 1Overview6
  • 1.1Statement of Report6
  • 1.2Scope of This Report6
  • 1.3Objectives7
  • 1.4Methodology8
  • 1.5Aims of This Report9
  • 1.6Executive Summary9
  • 1.7Trends and Conclusions10
  
  
• 2Introduction to Microscopy Markets11
  • 2.1Overview of Microscopy Technologies11
    • 2.1.1Introduction11
    • 2.1.2Basic Optical Microscopy (OM)11
    • 2.1.3Electron Microscopy (EM) and Other Charged-Particle Technologies12
    • 2.1.4Advanced Optical Microscopy13
    • 2.1.5Scanning Probe Microscopy (SPM)13
    • 2.1.6Fourier Transform Infrared Microscopy (FT-IR)14
    • 2.1.7Ultraviolet Microscopy (UVM)14
    • 2.1.8Scanning Acoustic Microscopy (SAM)14
    • 2.1.9X-Ray Microscopy / Microtomography (MCT, XMT, Micro-CT)14
  • 2.2Market Perspective14
  • 2.3Market Analysis15
    • 2.3.1Market Size16
    • 2.3.2Market Share17
    • 2.3.3Key Players17
    • 2.3.4Competition18
    • 2.3.5Barriers to Growth18
    • 2.3.6Market Drivers18
  • 2.4Purchasers\' Perspectives19
  
  
• 3In-Depth Discussion of Optical (Light) Microscopy (OM)21
  • 3.1Lens Systems22
  • 3.2Resolution23
  • 3.3Illumination Systems23
  • 3.4Innovations24
    • 3.4.1Stereo Microscopes24
  • 3.5Major Applications of Optical Microscopy25
    • 3.5.1Semiconductor Manufacturing25
    • 3.5.2Automated Medical Imaging26
    • 3.5.3Market Drivers for Automated Systems for Semiconductor and Medical Applications28
    • 3.5.4Real-Time Imaging28
    
    
• 4In-Depth Discussion of Light-Based Fluorescence, Multi-Photon and Confocal Microscopy29
  • 4.1Fluorescence Microscopy29
  • 4.2Total Internal Reflection Fluorescence Microscopy (TIRFM)30
  • 4.3Multi-Photon Microscopy30
    • 4.3.1Basic Principles30
    • 4.3.2Lasers30
    • 4.3.3Fluorophores for Multi-Photon Work31
    • 4.3.4Uncaging31
    • 4.3.5Autofluorescence31
  • 4.4Laser Scanning Confocal Microscopy (Confocal, LSCM)31
    • 4.4.1Basic Principles32
    • 4.4.2Confocal System Types33
    • 4.4.3Photobleaching33
  • 4.5High-Throughput Fluorescence and Confocal Imaging Systems33
  • 4.6Major Players and Products in Optical, Fluorescence, Multi-Photon and Confocal Microscopy34
    • 4.6.1BD (Becton, Dickinson and Company)34
    • 4.6.2KLA-Tencor Corporation34
    • 4.6.3Korima, Inc.35
    • 4.6.4Leica Microsystems, Inc.35
    • 4.6.5Nikon Instruments, Inc.38
    • 4.6.6Nanomics Imaging, Inc.39
    • 4.6.7Olympus Imaging America, Inc.39
    • 4.6.8Veeco Instruments, Inc.40
    • 4.6.9Carl Zeiss Microimaging, Inc.41
    • 4.6.10Modular Confocal Scanners42
    
    
• 5In-Depth Discussion of Scanning Probe Microscopy (SPM), Including Near-Field (NSOM) and Atomic Force Microscopy (AFM)44
  • 5.1Introduction44
  • 5.2Near-Field Scanning Optical Microscopy (NSOM)44
    • 5.2.1Resonance Frequency45
    • 5.2.2Aperture45
    • 5.2.3Reflection Mode45
  • 5.3Near-Field Scanning Thermal Microscopy (NThM)45
  • 5.4Atomic Force Microscopy (AFM)45
    • 5.4.1Semiconductor Applications46
    • 5.4.2Magnetic Material Applications46
    • 5.4.3Electrochemical Applications46
    • 5.4.4Life Sciences Applications46
  • 5.5Major Players and Products in Scanning Probe Microscopy (Including Near-Field and Atomic Force)47
    • 5.5.1Agilent Technologies47
    • 5.5.2Asylum Research47
    • 5.5.3JEOL USA, Inc.47
    • 5.5.4KLA-Tencor Corporation48
    • 5.5.5Nanonics Imaging, Ltd.48
    • 5.5.6Omicron NanoTechnology GmbH49
    • 5.5.7Veeco Instruments, Inc.49
    • 5.5.8WITec Instruments Corp.51
    
    
• 6In-Depth Discussion of Infrared and Ultraviolet Microscopy52
  • 6.1Fourier-Transfer Infrared Microscopy (FT-IR)52
  • 6.2Ultraviolet Microscopy (UVM)52
  • 6.3Major Players and Products for Infrared and Ultraviolet Microscopy53
    • 6.3.1Bruker Optics, Inc.53
    • 6.3.2Craic Technologies53
    • 6.3.3KLA-Tencor Corporation53
    • 6.3.4Korima, Inc.54
    • 6.3.5Thermo Scientific54
    
    
• 7In-Depth Discussion of Scanning Acoustic Microscopy, X-Ray Microtomography and Raman Spectroscopic Microscopy55
  • 7.1Scanning Acoustic Microscopy (SAM)55
  • 7.2X-Ray Microtomography (CTM, Micro-CT)56
  • 7.3Raman Spectroscopic Microscopy56
  
  
• 8Major Players and Products in Acoustic Microscopy, X-Ray Microtomography and Raman Microscopy58
  • 8.1Major Players in Acoustic Microscopy58
    • 8.1.1Sonix, Inc.58
    • 8.1.2Sonoscan, Inc.58
  • 8.2Major Players in X-Ray Microtomography59
    • 8.2.1Cameca Instruments, Inc.59
    • 8.2.2SkyScan59
  • 8.3Major Players in Raman Microscopy59
    • 8.3.1Horiba Jobin Yvon, Inc.59
    • 8.3.2Renishaw, Inc.60
    • 8.3.3Thermo Scientific60
    
    
• 9In-Depth Discussion of Electron Microscopy (EM) and Related Charged-Particle Systems61
  • 9.1Transmission Electron Microscope (TEM)61
    • 9.1.1Electron Sources62
  • 9.2Scanning Electron Microscope (SEM)63
    • 9.2.1Rastering63
    • 9.2.2Exploring the Sample64
    • 9.2.3Types of Image64
    • 9.2.4Environmental SEM (ESEM) and Variable-Pressure SEM (VPSEM)65
    • 9.2.5Low-Voltage SEM66
    • 9.2.6Tabletop Models66
    • 9.2.7Applications66
  • 9.3Scanning/Transmission Electron Microscope (STEM)66
  • 9.4Electron Probe Microanalyzer (EPMA, Microprobe)67
  • 9.5Auger Electron Microscopy/Spectroscopy (AES, AEM, Auger)68
  • 9.6Electron Beam (E-Beam) Lithography68
  • 9.7Focused Ion Beam (FIB) and Dual-Beam Microscopes69
  • 9.8Secondary Ion Mass Spectrometry (SIMS)69
  • 9.9X-Ray Photoelectron Spectroscopy (XPS)/ Electron Spectroscopy for Chemical Analysis (ESCA)70
  • 9.10Scanning Helium Ion Beam Microscopy (SHIM)70
  
  
• 10Ancillary Analytical Attachments71
  • 10.1Common/Historical Attachments71
    • 10.1.1Energy-Dispersive (EDS) and Wavelength-Dispersive (WDS) X-ray Microanalyzers71
    • 10.1.2Electron Backscatter Diffraction (EBSD)71
    • 10.1.3Cathodoluminescence (CL)71
    • 10.1.4X-Ray Microtomography71
    • 10.1.5Raman Spectroscopy72
    
    
• 11Major Players and Products in Electron Beam and Other Charged-Particle Beam Microscopies73
  • 11.1Cameca Instruments, Inc.73
  • 11.2FEI Company74
  • 11.3Hitachi High Technologies America, Inc.79
  • 11.4JEOL USA, Inc.81
  • 11.5KLA-Tencor Corporation86
  • 11.6Omicron NanoTechnology GmbH86
  • 11.7Vistec Lithography, Inc.87
  • 11.8Carl Zeiss SMT Corporation88
  
  
• 12Company Profiles90
  • 12.1Applied Materials, Inc.90
  • 12.2Applied Precision, Inc.91
  • 12.3Becton, Dickinson and Company91
  • 12.4Bio-Rad Laboratories, Incorporated92
  • 12.5Bruker Optics93
  • 12.6Buehler93
  • 12.7Cameca94
  • 12.8Carl Zeiss, Inc.94
  • 12.9Danish Micro Engineering A/S96
  • 12.10FEI Company97
  • 12.11Gatan98
  • 12.12Genetix99
  • 12.13Hitachi, Ltd.99
  • 12.14Inami Corp.101
  • 12.15IRIS International101
  • 12.16JEOL103
  • 12.17KLA-Tencor Corporation104
  • 12.18Leica Microsystems (part of Danaher Corporation)107
  • 12.19Medical Integrated Services (MIS)108
  • 12.20Nanonics Imaging, Ltd.108
  • 12.21Nikon, Inc.109
  • 12.22NT-MDT110
  • 12.23Obducat-CamScan110
  • 12.24Olympus Corporation111
  • 12.25Omicron Nanotechnology113
  • 12.26Pacific Nanotechnology113
  • 12.27Park Systems (formerly PSIA)113
  • 12.28PerkinElmer113
  • 12.29Quesant Instruments119
  • 12.30Questar Corporation119
  • 12.31Schott North America120
  • 12.32Shimadzu Corporation121
  • 12.33SII NanoTechnology121
  • 12.34Thermo Fisher Scientific, Inc.121
  • 12.35TM Microscopes (ThermoMicroscopes)125
  • 12.36TriPath Imaging, Inc.126
  • 12.37Veeco Instruments126
  • 12.38WITec (Wissenschaftliche Instrumente und Technologie) GmbH128
  
  
• 13Company Directory129

 

INDEX OF FIGURES

Figure 2.1: Global Market for Microscopes, Accessories and Supplies, 2003-201216

Figure 3.1: Basic Components of the Optical Microscope21

Figure 3.2: Stereo Microscope24

INDEX OF TABLES

Table 2.1: Global Market for Microscopes and Accessories, 2007-201316

Table 2.2: Global Market for Optical Microscopes and Accessories17

Table 2.3: Global Market for Charged Particle Microscopes and Accessories17

Table 2.4: Global Market for Scanning Probe Microscopes and Accessories17

Table 3.1: Basic Components of the Optical Microscope21

Table 5.1: Types of Scanning Probe Microscopes44

 

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