Vaccines 2009: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry
The global market for human vaccines has experienced strong growth through 2008 and this is expected to continue through the forecast period. Growth will be fueled by new product introductions and rising usage in all regions.
Vaccines 2009: Key Players, and Critical Trends in a Fast-Changing Industry examines the market for vaccines used in humans to previous various types of disease. Sales estimates for each market segment represent global revenues and are expressed in current dollars. Estimates are provided for the historic 2008 period and forecasts are provided through 2013.
Key features of the current vaccines market are:
- Vaccine makers are now advertising directly to the public with growing DTC budgets. The report identifies the possible market impact of this new trend.
- The economy has impacted vaccine sales with more people unable to make required out of pocket payments for vaccination.
- New categories of vaccines, such as allergy vaccines, are becoming more prominent, and have been included in our forecasts.
- Several major new products, including Wyeth's Prevnar 13, are on the horizon. The market impact of new products is discussed.
- Two major mergers - Pfizer/Wyeth and Merck/Schering-Plough, will impact the industry and this is considered in our market analysis.
Few areas of pharmaceuticals have seen the fast-moving developments in the marketplace that the vaccine market has in 2008. New products and better than expected profits have transformed the vaccine marketplace. Continued sales of influenza vaccines and cervical cancer vaccines have provided a foundation for growth in the adult market. The competitive dynamics have changed with mergers, and many new products are on the way.
This exhaustive research and analysis has been built from interviews with key decision makers in the market and includes the following:
- Review of Products in the Market
- Current World Market Size for Pediatric and Adult Vaccines
- Segmented Revenues and Forecasts to 2013 by Category
- Over 45 Charts and Tables To Make Information Accessible
- Discussion of The Current Economy and Vaccines, Immunization Refusal, Swine/Avian Flu and Other Pandemics, Delivery Sys and other Trends in the Vaccine Market
- Important Vaccines and Immunization Schedules and Statistics
- Profiles of 15 Key Vaccine Companies
- Thorough Review of the Vaccine Pipeline and Possible Impact of New Products
Who are the main players in the vaccine market? What opportunities are available for pharmaceutical companies or investors from this market? What are the potential challenges vaccine competitors must deal with? What will be the impact of the first successful cancer product? What is the significance of at least one major acquisition to affect this industry? These questions and more are tackled in this report.
Current revenues and revenue forecasts to 2013 are included for the following pediatric vaccine categories:
- DTaP & DTP Vaccines
- Hep Vaccines
- HiB Vaccines
- MMR Vaccines
- Combination Vaccines
- Pneumococcal Vaccines
- Polio Vaccines
- Varicella Vaccines
- Other Pediatric Vaccines
As well as Revenues and Forecasts to 2012 for the following adult vaccine categories:
- Influenza Vaccines
- Hepatitis Vaccines
- Pneumococcal Vaccines
- Travel, DT and other Adult Vaccines
- Cervical Cancer
This is a rapidly changing marketplace and knowledge of the R&D pipeline is essential to truly understand what is happening in vaccines. Vaccines in development are discussed in this report, including vaccines for the following conditions:
- Enterotoxigenic Escherichia coli
- Parainfluenza Virus Type 3
- Pneumococcal Vaccines
- Respiratory Syncytial Virus
- Cancers
- Cholera
- HIV/AIDS
- Helicobacter Pylori
- Malaria
- Rabies
- Tuberculosis
- West Nile Virus
This report was created with a primary research effort. Historical information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts’ reports and other sources. Interviews with company representatives and other experts were conducted to capture the perspectives from industry participants’ point of view and assess trends, and form the basis of the forecasting and competitive analysis.
Table of Contents
- CHAPTER ONE: EXECUTIVE SUMMARY
- THE GLOBAL VACCINES INDUSTRY
- Scope And Methodology
- Overview
- Pediatric Preventative Vaccines
- The Market
- Adult Preventative Vaccines
- The Market
- Total Market
- Issues and Trends
- CHAPTER TWO: INTRODUCTION TO VACCINES
- A Brief History: The Development of Vaccines
- The Immune Response
- Mechanism of Action
- Types of Vaccines
- Attenuated (Weakened) Live Viruses
- Killed (Inactivated) Viruses
- Toxoid Vaccines
- Genetically Engineered/Modified Vaccines
- Subunit Vaccines
- Conjugate Vaccines
- DNA Vaccination
- Vaccine Approval Process
- CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES
- Introduction
- Childhood Immunization in the United States
- Childhood Immunization Rates
- Challenges to the Vaccine Delivery System
- Recommended Childhood Immunization Schedule
- State Immunization Recommendations
- Pediatric Vaccine Products
- BCG
- Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
- Diphtheria
- Pertussis
- Tetanus
- Hepatitis B
- Poliomyelitis
- Enterotoxigenic Escherichia coli
- Haemophilus Influenzae Type B
- Hepatitis A
- Measles, Mumps and Rubella
- Measles
- Mumps
- Rubella
- Meningococcal Disease
- Parainfluenza Virus Type 3
- Pneumococcal Conjugate
- Respiratory Syncytial Virus
- Rotavirus
- Varicella
- Pediatric Vaccines in Development
- Global Initiatives for Vaccine Research
- Cost of Vaccines in the United States
- The World Market for Pediatric Preventive Vaccines
- Total Market Size and Forecast
- Hepatitis Vaccine Market
- Market Analysis
- Leading Products and Competitors
- Haemophilus Influenzae Type B Vaccine Market
- Market Analysis
- Leading Products and Competitors
- Measles, Mumps and Rubella Vaccines
- Market Analysis
- Combination Vaccines Market
- Market Analysis
- Leading Products and Competitors
- Pneumococcal Vaccine
- Leading Products and Competitors
- Poliovirus Vaccine
- Market Analysis
- Leading Products and Competitors
- Varicella Vaccines
- Market Analysis
- Leading Products and Competitors
- Other Vaccines Market
- Market Analysis
- Leading Products and Competitors
- CHAPTER FOUR: ADULT PREVENTIVE VACCINES
- Introduction
- Adult Vaccine-Preventable Diseases: Facts and Figures
- Global Virological Surveillance Program
- Recommendations for Adult Immunizations
- WHO International Health Regulations
- Adult Vaccine Products
- Allergy
- BCG
- Cancer
- Cervical Cancer
- Cholera
- Diphtheria-Tetanus
- Helicobacter Pylori
- Hepatitis
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Herpesvirus
- HIV/AIDS
- Influenza
- Japanese Encephalitis
- Leishmaniasis
- Malaria
- Pneumococcal Disease
- Rabies
- Shingles
- Tuberculosis
- Typhoid Fever
- West Nile Virus
- Yellow Fever
- Adult Vaccines in Development
- Global Initiatives for Vaccine Research
- The World Market for Adult Preventive Vaccines
- Total Market Size and Forecast
- Cervical Cancer Market
- Market Analysis
- Leading Products and Competitors
- Hepatitis Market
- Market Analysis
- Leading Products and Competitors
- Influenza Vaccine Market
- Market Analysis
- Leading Products and Competitors
- Market Analysis
- Leading Products and Competitors
- Travel, DT, and Miscellaneous Vaccine Market
- Market Analysis
- Leading Products and Competitors
- CHAPTER FIVE: VACCINES MARKET SUMMARY
- Trends Driving the Vaccines Market
- Market Size and Forecast
- Vaccine Market Competitors
- Pediatric Vaccines
- Major Manufacturer’s Market Share
- Adult Vaccines
- Major Manufacturer’s Market Share
- CHAPTER SIX: ISSUES AND TRENDS
- Vaccine Safety
- Refusal to Immunize
- Post-Licensure Surveillance
- Vaccine Adverse Event Reporting System
- The Vaccine Safety Datalink Project
- Phase IV studies
- The Vaccine Injury Compensation Program
- World Health Organization
- Other Initiatives
- The Future of Vaccine Safety
- Vaccine Shortages
- Preventing Shortages in the Developed Countries
- Financial incentives
- Equitable pricing
- Vaccine stockpiles
- Preventing Shortages in Developing Nations
- Vaccine bonds
- Economic Effects
- Industrialized Nations
- Developing Nations
- Preventing Pandemics
- U.S. National Vaccine Plan
- Vaccines and Bioterrorism
- Overview
- Project Bioshield Act of 2004
- National Bio and Agro-Defense Facility
- Vaccine Treatment and Evaluation Units
- Anthrax
- Smallpox
- Plague
- Botulism
- Tularemia
- Viral Hemorrhagic Fevers
- DNA Vaccination
- Innovations in Vaccine Delivery Systems
- Edible Vaccines
- Mucosal Delivery
- Intranasal Delivery
- Vaccine Patches
- DTC Advertising
- CHAPTER SEVEN: COMPANY PROFILES
- Acambis plc
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- AlphaVax, Inc.
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Bavarian Nordic A/S
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Baxter Healthcare
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Celldex Therapeutics
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Crucell
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Emergent Biosolutions
- History and Lines of Business
- Strategic Acquisition and Alliance
- Vaccine Products
- Financial
- GlaxoSmithKline
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Medimmune
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Merck & Co. Inc
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Nabi Biopharmaceuticals
- History and Lines of Business
- Strategic Alliance
- Vaccine Products
- Financial Information
- Novartis
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- History and Lines of Business
- Strategic alliances
- Vaccine products
- Financial Information
- Pharmexa
- History and Lines of Business
- Strategic alliances
- Vaccine Products
- Financial Information
- Sanofi Pasteur
- History and Lines of Business
- Strategic Alliances
- Vaccine Products
- Financial Information
- Wyeth
- History and Lines of Business
- Vaccine Products
- Financial Information
- APPENDIX: COMPANY DIRECTORY LIST OF EXHBITS
- CHAPTER ONE: EXECUTIVE SUMMARY
- Figure 1-1: World Market for Pediatric Vaccines 2004-2013
- Figure 1-2: World Market for Adult Vaccines 2004-2013
- CHAPTER TWO: INTRODUCTION TO VACCINES
- Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2008
- Table 2-2: Vaccine-Preventable Diseases, April 2009
- Table 2-3: VAERS Table of Reportable Events Following Vaccination
- Table 2-3 (cont.): VAERS Table of Reportable Events Following Vaccination
- CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES
- Table 3-1: Global Immunization Rates by Vaccine Type 2007
- Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 2000-2007
- Table 3-3: U.S. Recommended Immunization Schedule for Children Ages 0 Through 6 Years, 2009
- Table 3-4: U.S. Recommended Immunization Schedule for Adolescents Ages 7 to 18 Years, 2009
- Table 3-5: Selected Pediatric Vaccines in Development, April 2009
- Table 3-6: World Market for Pediatric Vaccines by Type (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others) 2004-2013 Revenues (in millions)
- Figure 3-1: Market Share of Pediatric Vaccines by Type 2008 (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)
- Figure 3-2: Market Share of Pediatric Vaccines, by Type 2013 (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)
- Table 3-7: World Pediatric Hepatitis Vaccine Market 2004-2013
- Table 3-8: World Hib Vaccine Market, 2004-2013
- Table 3-9: World MMR Vaccines Market 2004-2013
- Table 3-10: World Combination Vaccines Market 2004-2013
- Table 3-11: World Pediatric Pneumococcal Vaccine Market 2004-2013
- Table 3-12: World Poliovirus Vaccine Market 2004-2013
- Table 3-13: World Varicella Vaccine Market 2004-2013
- Table 3-14: Other Vaccines Market 2004-2013
- CHAPTER FOUR: ADULT PREVENTIVE VACCINES
- Table 4-1: Universal Adult Immunization Schedule 2009
- Table 4-2: Adult Immunization Schedule for Populations with Special Medical Conditions, 2008
- Table 4-3: Initiatives to Require HPV Vaccination by U.S. State, 2009
- Table 4-4: WHO Pandemic Classification Schedule
- Table 4-5: Selected Adult Preventive Vaccines in Development, 2009
- Table 4-6: World Market for Adult Preventive Vaccines by Type (Hepatitis, Influenza, Pneumococcal, Travel/DT/Misc.), 2004-2013 Revenues (in millions)
- Figure 4-1: Market Share of Adult Vaccines, by Type, 2009
- Figure 4-2: Market Share of Adult Vaccines, by Type, 2013
- Table 4-7: World Cervical CancerVaccine Market 2004-2013
- Table 4-8: World Hepatitis Vaccine Market 2004-2014
- Table 4-9: World Influenza Vaccine Market 2004-2013
- Table 4-10: CDC Goal to Double Flu Immunization by 2010 Group and Estimated Immunization Rate (2000 vs 2010)
- Table 4-11: 2007 Estimated Population by Region and Selected Age Group (in millions)
- Table 4-12: World Pneumococcal Vaccine Market 2004-2013
- Table 4-13: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market 2004-2013
- CHAPTER FIVE: VACCINES MARKET SUMMARY
- Figure 5-1: Sales Growth of Vaccines vs. Pharmaceuticals 2004-2013
- Figure 5-2: World Market for Vaccines by Type 2004-2013
- Table 5-1: The World Vaccines Market by Vaccine Type 2004-2013 Revenues (in millions)
- Figure 5-3: World Market for Vaccines Share by Type, 2004, 2008 and 2013
- Table 5-2: Major Manufacturers’ Shares of the World Vaccine Market, 2008
- Figure 5-3: 2008 World Vaccines Market Share, by Leading Competitors
- Table 5-3: Major Manufacturer’s Shares of the World Pediatric Vaccine Market 2008
- Figure 5-5: Market Share of Pediatric Vaccines Market, 2008
- Table 5-4: Major Manufacturer’s Shares of the World Adult Vaccine Market 2008
- Figure 5-6: Market Share of Adult Vaccines Market 2008
- CHAPTER SIX: ISSUES AND TRENDS
- Table 7-1: Selected Companies/Laboratories Developing Biodefense Vaccines
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