Needle-Free Drug Injection Systems and Safety Syringes: The Market for Alternatives to Traditional Needle-Based Delivery
Biopharmaceutical research and development is sure to dramatically increase the number of injectable drugs coming to market over the next few years. While advanced drug delivery techniques continue to hold promise for unique methods of administration, the traditional injection is still the dominant paradigm. However, the staggering costs and intransigent safety problems associated with sharps, along with consumer demand and the move to alternate-site care, are pushing for alternatives to traditional needles and syringes faster than advanced delivery technologies can come online.
The alternative in the short term appears to be the growing industry of needle-free injection and safety-engineered syringes. These devices, ranging from simple sheathed safety needles to complex gas jet injection systems, are competing in a vigorous marketplace, some sectors of which are growing at an annual rate in excess of 20%.
This report analyzes the current world market for needle-free drug delivery injection systems and safety syringes in terms of dollar volume and unit sales and makes forecasts through 2009. Regional geographic segmentations are also provided through the forecast period in both units and dollars. The report discusses the market’s drivers and constraints and provided pertinent data on the epidemiology of needlestick injuries, the value of injectable drug markets, and other related issues and trends. It also profiles more than 25 companies involved in marketing or developing these devices, including Antares Pharma, Becton Dickinson, Bioject, D’Antonio Consultants International, Retractable Technologies, Safety Syringes Inc., and Tyco Healthcare.
Market forecasts are based on an examination of current market conditions and on investigations into the development of new products by key companies. The information presented in this report is the result of data gathered from company product literature and other corporate brochures and documents, as well as information found in the scientific and trade press. In addition, interviews were conducted with company executives, clinicians, researchers and public health officials.
Table of Contents
Chapter One: Executive Summary
- 1.1 Background and Perspective
- 1.2 Traditional Drug Delivery Systems
- 1.3 Need for Alternative Delivery Systems
- 1.4 Market Summary
- 1.4.1 Market Drivers
- 1.4.2 Market Challenges
- 1.4.3 Brief Market Forecast
- 1.5 Methodology
Chapter Two: Introduction
- 2.1 Risk and Prevention
- 2.2 Overview of Different Drug Delivery Systems
- 2.2.1 Polymers and Biomaterials
- 2.2.2 Oral Drug Delivery Systems
- 2.2.3 Pulmonary Drug Delivery
- 2.2.4 Drug Eluting Stents
- 2.2.5 Percutaneous Drug Delivery
- 2.2.6 Ophthalmic Drug Delivery
- 2.2.7 Colloidal Drug Delivery
- 2.2.8 Site Specific Delivery
- 2.2.9 Needle-Free Delivery
- 2.2.10 Safety Syringes
- 2.3 Key Medicines for Delivery
- 2.3.1 Insulin
- 2.3.2 Human Growth Hormone
- 2.3.3 Vaccines
- 2.4 Alternatives to Needle Delivery of Drugs
- 2.4.1 Needle-Free Systems
- 2.4.2 Safety Syringes
- 2.5 Factors Driving Development
- 2.5.1 Epidemiology of Injuries
- 2.5.1 Epidemiology of Bloodborne Virus Transmission
- 2.5.1.1 Hepatitis B Virus
- 2.5.1.2 Hepatitis C Virus
- 2.5.1.3 HIV
- 2.5.3 Cost of Needlestick Injuries
- 2.5.4 Prevention Approaches
- 2.6 Challenges and Issues
- 2.7 Needle-Free and Safety Syringe Drug Delivery Research
- 2.7.1 Microscission
- 2.7.2 Evolving Vaccine Delivery Technologies
- 2.7.2.1 Auto-Disable Syringes
- 2.7.2.2 Monodose Prefilled Injection Devices
- 2.7.2.3 Needle-Free Injections
- 2.7.2.4 Thermostable Vaccines
Chapter Three: Markets
- 3.1 Current Face of the Market
- 3.1.1 Safety and Cost as Major Drivers
- 3.1.2 Technology Development
- 3.1.5 Prefilled Devices and Non-Prefilled Devices.
- 3.1.4 Convenience and Compliance
- 3.1.5 Product Differentiation
- 3.1.6 Harm Reduction.
- 3.1.7 Opportunity
- 3.2 Human Growth Hormone
- 3.3 Insulin
- 3.4 Vaccines
- 3.4.1 Immunization Programs
- 3.4.2 Emerging Vaccines
- 3.4.3 Injection Concerns
- 3.5 Needlestick Injuries
- 3.6 Geographic Markets
Chapter Four: Corporate Profiles
- 4.1 Antares Pharma Inc.
- 4.2 Aradigm Corp.
- 4.3 Becton, Dickinson and Co.
- 4.4 Bioject Medical Technologies Inc.
- 4.5 BioValve Technologies Inc.
- 4.6 Cambridge Biostability Ltd.
- 4.7 D'Antonio Consultants International
- 4.8 Eastland Medical Systems Ltd.
- 4.9 Equidyne Systems
- 4.10 First Principals Inc.
- 4.11 Med-Design Corp.
- 4.12 Medical House PLC
- 4.13 Medical International Technologies
- 4.14 Medisys PLC
- 4.15 National Medical Products Inc.
- 4.16 New Medical Technology
- 4.17 Norwood Abbey Ltd.
- 4.18 Retractable Technologies Inc.
- 4.19 Roche (F. Hoffmann-La Roche Ltd.)
- 4.20 Serono Inc.
- 4.21 Safety Syringes Inc.
- 4.22 Smiths Medical (Smiths Group)
- 4.23 Sunder Group
- 4.24 Tyco Healthcare
- 4.25 Unilife Medical Solutions Ltd.
- 4.26 Univec Ltd.
List Of Exhibits
Chapter One: Executive Summary
- Exhibit 1-1: Summary: World Market for Drugs Delivered by Needle-FreeSystems 2005-2009
- Exhibit 1-2: Summary: World Market for Needle-Free Drug Injectors 2005-2009
- Exhibit 1-3: World Market for Safety Syringes 2005-2009
Chapter Two: Introduction
- Exhibit 2-1: Immunization Cost Analysis
- Exhibit 2-2: Adult Preventable Disease Statistics
- Exhibit 2-3: Advantages of Needle-Free Delivery
- Exhibit 2-4: Annual Injury Rates for Healthcare and Sanitary Service Personnel from Sharps in Found Medical Waste
- Exhibit 2-5: Work Locations Where Fluid Exposures Occurred(NaSH 6/95 to 10/01)
- Exhibit 2-6: Circumstances Associated with Hollow-Bore Needle Injuries(NaSH 6/95 to 12/01)
- Exhibit 2-7: Devices Involved in Percutaneous Injuries (NaSH)
- Exhibit 2-8: Infections Transmitted via Sharps, Injuries during PatientCare and/or Laboratory/Autopsy
- Exhibit 2-9: Estimated Number of People Living with HIV 2000-2004
Chapter Three: Markets
- Exhibit 3-1: Prevalence of Diabetes in the Seven Major World HealthcareMarkets by Type 2004-2014
- Exhibit 3-2: World Market for Syringes Dollar Volume 2005-2009
- Exhibit 3-3: World Market for Syringes Dollar Volume by GeographicRegion 2005-2009
- Exhibit 3-4: World Market for Syringes Unit Sales 2005-2009
- Exhibit 3-5: World Market for Syringes Unit Sales by GeographicRegion 2005-2009
- Exhibit 3-6: World Market for Safety Syringes Dollar Volume 2005-2009
- Exhibit 3-7: World Market for Safety Syringes Dollar Volume by Geographic
- Region 2005-2009
- Exhibit 3-8: World Market for Safety Syringes Unit Sales 2005-2009
- Exhibit 3-9: World Market for Safety Syringes Unit Sales by GeographicRegion 2005-2009
- Exhibit 3-10: Market Segments for Safety Syringes Percentage by Distribution Channel
- Exhibit 3-11: Worldwide Safety Syringe Market Market Share of Leading Competitors
- Exhibit 3-12: World Market for Drugs Delivered by Needle-FreeSystems 2005-2009
- Exhibit 3-13: World Market for Needle-Free Drug Injectors DollarVolume 2005-2009
- Exhibit 3-14: World Market for Needle-Free Drug Injectors DollarVolume by Geographic Region 2005-2009
- Exhibit 3-15: World Market for Needle-Free Drug Injectors UnitSales 2005-2009
- Exhibit 3-16: World Market for Needle-Free Drug Injectors Unit Sales by Geographic Region 2005-2009
- Exhibit 3-17: Status of Selected Needle-Free Injection Systems and Safety Syringes
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