Since more than 11 million Americans report pain as a significant disability, there’s no question that pain management is big business for healthcare practitioners today, and one area that market watchers need to understand. When viewed globally, there is a large underserved population for pain management medications, which indicates growth in what is now a 26 billion-dollar plus industry.
How big will the pain management drug and device market get in the next four years? Who are the key players that will lead this growth? What are the fastest-growing segments of pain management and which segments will just keep pace or fall? How will the Vioxx recall and Tylenol’s association with liver damage affect pain management market as a whole? What new drugs are in the pipeline and how are they expected to change the competitive landscape?
Kalorama’s World Market for Pain Management Drugs and Devices is your guide to the pain management marketplace. In great detail, the report analyzes the global marketplace for pain management products currently available and those in the product pipeline. Segmenting the market by pain indication, the report provides size, growth, and forecasts to 2010 for nine major pain indications:
Burn Pain
Cancer Pain
Dental/Facial Pain
Migraine Headache Pain
MusculoSkeletal Pain
Neuropathic Pain
Obstetrical Pain
Pediatric Pain
Surgical and Trauma Pain
The truly global perspective of this report takes this information one step further, breaking down each of those segments by geography, providing current revenues and forecast revenues to 2010 by region:
United States
Europe
Japan
Rest of World
A comprehensive survey, Kalorama’s World Market for Pain Management Drugs and Devices provides information and market data on the pain management medical device sector as well, including modality/product descriptions, revenue forecasts, and regional breakdowns through 2010.
Competitive information on pipeline and product offerings as well as market share by top drug are provided. Extensive discussions of issues and trends, including chapters devoted to drug delivery and alternative pain therapies, and profiles of selected companies round out the comprehensive look at the market.
Kalorama’s trusted information-gathering process relies on more than just research into company and government data. Over 51 industry executives were interviewed to provide the basis for the market data and forecasts made in this report. The information and analysis presented in this report are based on extensive interviews with senior management of top companies and conference participants (business and clinical) in the pain management market. Background information was obtained from a comprehensive search of published literature and reports obtained from various government, business, medical trade, and international journals. Interviews were also used to confirm and/or adjust market size estimates, as well as in formulating market projections.
Table of Contents
Chapter One: Executive Summary
Introduction
Scope and Methodology
Size and Growth of the Market
Issues and trends
Leading Competitors
Chapter Two: Introduction and Overview
Definition of Pain
Magnitude of Pain
Physiology of Pain
Transduction
Transmission
Pain Pathways
Types of Pain
Measurement of Pain
Treatment Modalities—Pharmacologic Management
Analgesic Ladder
Step I Drugs
Step II Drugs
Step III Drugs
Recommended Drug and Route
Administration Routes
Titration
Treatment Modalities—Non-pharmacologic Management
Device-Based Methods
Cognitive-Behavioral Therapies
Multidisciplinary Pain Management
Demographics and Epidimiology
Chapter Three: Treatment Markets and Forecasts
Burn Pain
Overview of Top Products
Opiate Agonists—Natural Alkaloids
Opiate Agonists—Semisynthetic Analogs
Opiate Agonists—Synthetic Compounds
Market Size and Growth
Markets by Region
Cancer Pain
Overview of Top Products
Opiate Agonists- Natural Alkaloids
Opiate Agonists-Semisynthetic Analogs
Opiate Agonists- Synthetic Compounds
Phenylpiperdine Compounds
New Products
Market Size and Growth
Market by Region
Dental/Facial Pain
Overview of Top Products
Opiate Agonists- Natural Alkaloids
Opiate Agonists-Semisynthetic Analogs
Opiate Agonists- Synthetic Compounds
Opiate Agonist-Antagonists
Centrally-acting Synthetic Analgesic Compounds
New Products
Market Size and Growth
Markets by Region
Migraine Headache Pain
Overview of Top Products
Selective Serotonin Agonists
New Products
Market Size and Growth
Markets by Region
Musculoskeletal Pain
Overview of Top Products
Phenylpiperidine Compounds
Cox-2 Inhibitors
Non-steroid Anti-inflammatory Drugs
Opioid Agonists- Natural Alkaloids
Hyaluronate Sodium Derivative
New Products
Market Size and Growth
Markets by Region
Neuropathic Pain
Overview of Top Products
Antiseizure Drugs
Opiate Agonists- Natural Alkaloids
Opiate Agonists-Semi-Synthetic Analogs
Phenylpiperidine Compounds
New Products
Market Size and Growth
Markets by Region
Obstetrical Pain
Overview of Top Products
Opiate Agonists—Synthetic Compounds
Opiate Agonist—Antagonists
Centrally Acting Synthetic Analgesic Compounds
Market Size and Growth
Markets by Region
Pediatric Pain
Overview of Top Products
Opiate Agonist-Antagonists
Indole Analogs
Opiate Agonists-Semisynthetic Analogs
Opiate Agonists- Natural Alkaloids
Market Size and Growth
Markets by Region
Surgical and Trauma Pain
Overview of Top Products
Opiate Agonists—Natural Alkaloids
Opiate Agonists—Semisynthetic Analogs
Opiate Agonists—Synthetic Compounds
Opiate Agonist—Antagonists
Centrally Acting Synthetic Analgesic Compounds
New Product Approvals
Market Size and Growth
Markets by Region
Chapter Four: Drug Delivery
Oral Drug Delivery
Parenteral Drug Delivery
Transdermal
Patient Controlled Analgesia
Intrathecal Implants
Electrotransport Drug Delivery
Drug Delivery in Development
Chapter Five: Pain Management Devices
Transcutaneous Electrical Nerve Stimulators
Neuromuscular Stimulators
Spinal Cord Stimulators and Peripheral Nerve Stimulators
PCAs and Intrathecal Pain Pumps
Other Miscellaneous Devices
Cranial Electrotherapy Stimulation
Electrothermal and Electromagnetic Therapy
Thermography
Market Size and Growth
Markets by Region
Chapter Six: Alternative Treatment Modalities
Acupuncture
ETPS Neuropathic acupuncture
Low Level Laser Light Therapy
Biofeedback
Relaxation
Music and Pain Relief
Wave Therapy
Acupressure
Massage Therapy
Natural Supplements in Pain Management
Bioelectromagnetism
CHapter Seven: Issues and Trends
Overview
Barriers to Pain Management
Cancer Pain
Education
Chronic Pain and Work
Managed Care Pain Management
The Fifth Vital Sign
Use of Psychopharmacology in Chronic Pain
Vioxx Recall
COX-1 and COX-2 Enzyme Interference
use of Botulinum Neurotoxin
Research and Development
Accelanyl
Arcoxia
Cellegesic
Chronogesic
CIP Tramadol
Hyalgan
Imitrex Nasal Spray (Pediatric)
Pennsaid
Prexige
Trexima
406381
ALGRX 3268
BEMA-Fentanyl
Bicifadine
Dynastat
HCT 3012
IV APAP
Lacosamide Oral
LidoPain SP
M6G
Memantine (Namenda)
Neurodex
NGX 4010 (Transacin)
OxyTrex
OMS 103 HP
Oros Hydromorphone
Rapinyl
Remoxy
Rylomine
Sativex
Tapentadol
Tavocept
Tramadol
TQ-1017
The Elderly
Oxycontin Issues
Constant Pain Phenomenon
Tylenol and Liver Damage
Pain Medication Treatment Confusion
Restrictive Romanian National Drug Policies
Transporter Discovery
Marijuana and Pain Control
New Targets
Drug Abuse and Pain Control
Chapter Eight: Market Summary
Total Market Size and Forecast
Top Revenue Producing Products
Competitor Analysis
Chapter Nine: Corporate Profiles
Abbott Laboratories
AstraZeneca plc.
Baxter International, Inc
Boehringer Ingelheim
Bristol-Myers Squibb Company
Cephalon Inc.
Endo Pharmaceutical Holdings Inc
GlaxoSmithKline plc
Javelin Pharmaceuticals
Johnson & Johnson, Inc
Medtronic, Inc
Merck & Company
Novartis International AG
Ortho-McNeil (J&J)
Pain Therapeutics
Pfizer, Inc
Purdue Pharma
Sanofi-Aventis
TEVA Pharmaceutical Industries, Ltd.
Watson Pharmaceuticals, Inc.
Wyeth
Appendix: Company Directory
List of Exhibits
chapter one: Executive Summary
Table 1-1: Total World Pain Management Market 2004-2010
Table 1-2: World Market for Top Pain Management Treatments Revenues and Segments of Participation by Major Areas of Participation 2006
Chapter Two: Introduction and Overview
Table 2-1: Most Commonly Used Pain Quality Descriptors
Table 2-2: Pharmacokinetics of Step I Analgesics by Product (Name, Typical
Dose, Approximate Equivalent, Onset Time, Peak Effect Time,Duration)
Table 2-3: Pharmacokinetics of Step II Analgesics (Name, Typical Dose, Approximate Equivalent, Onset Time, Peak Effect Time, Duration)
Table 2-4: Pharmacokinetics of Step III Analgesics (Name, Typical Dose, Onset
Time, Peak Effect Time, Duration)
Table 2-5: Prevalence of Selected Pain-Related Conditions (RheumatoidArthritis, Back Pain, Cancer Pain, Migraine, Neuropathic Pain, Osteoarthritis)
Chapter three: Treatment Markets and Forecasts
Table 3-1: World Market for Burn Pain Market 2004-2010
Figure 3-1: World Market for Burn Pain Management 2004-2010
Table 3-2: World Market for Burn Pain Management by Geographic Region(United States, Europe, Japan, ROW) 2004-2010
Figure 3-2: Regional Markets for Burn Pain Management 2004-2010
Table 3-3: World Market for Cancer Pain Management 2004-2010
Figure 3-3: World Market for Cancer Pain Management 2004-2010
Table 3-4: World Market for Cancer Pain Management by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-4: Regional Markets for Cancer Pain Management 2004-2010
Table 3-5: The World Market for Dental/Facial Pain Management 2004-2010
Figure 3-5: The World Market for Dental/Facial Pain Management 2004-2010
Table 3-6: World Market for Dental/Facial Pain Management by Geographic
Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-6: Regional Markets for Dental/Facial Pain Management 2004-2010
Table 3-7: World Market for Migraine Pain Management 2004-2010
Figure 3-7: World Market for Migraine Pain Management 2004-2010
Table 3-8: World Market for Migraine Pain Management by Geographic
Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-8: Regional Markets for Migraine Pain Management 2004-2010
Table 3-9: World Market for Musculoskeletal Pain Management 2004-2010
Figure 3-9: World Market for Musculoskeletal Pain Management 2004-2010
Table 3-10: World Market for Musculoskeletal Pain Management by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-10: Regional Markets for Musculoskeletal Pain Management 2004-2010
Table 3-11: World Market for Neuropathic Pain Management 2004-2010
Figure 3-11: World Market for Neuropathic Pain Management 2004-2010
Table 3-12: World Market for Neuropathic Pain Management by Geographic
Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-12: Regional Markets for Neuropathic Pain Management 2004-2010
Table 3-13: World Market for Obstetrical Pain Management 2004-2010
Figure 3-13: World Market for Obstetrical Pain Management 2004-2010
Table 3-14: World Market for Obstetrical Pain Management by Geographic
Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-14: Regional Markets for Obstetrical Pain Management 2004-2010
Table 3-15: World Market for Pediatric Pain Management 2004-2010
Figure 3-15: Total World Pediatric Pain Market 2004-2010
Table 3-16: World Market for Pediatric Pain Management by Geographic
Region (United States, Europe, ROW) 2004-2010
Figure 3-16: Regional Markets for Pediatric Pain Management 2004-2010
Table 3-17: World Market for Surgical and Trauma Pain Management 2004-2010
Figure 3-17: World Market for Surgical and Trauma Pain Management2004-2010
Table 3-18: World Market for Surgical and Trauma Pain Management by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
Figure 3-18: Regional Markets for Surgical and Trauma Pain Management2004-2010
chapter five: Pain Management Devices
Table 5-1: World Market for Pain Management Devices 2004-2010
Figure 5-1: World Market for Pain Management Devices 2004-2010
Table 5-2: World Market for Pain Management Devices by Geographic Region (United States, Europe, Japan, ROW) 2004-2010
Figure 5-2: Regional Markets for Pain Management Devices 2004-2010
Chapter six: Alternative Treatment Modalities
Table 6-1: Pain Management Supplements in Clinical Trials
Chapter Seven: Issues and Trends
Table 7-1: Pain Management Products in Development by Phase (Product,
Active Ingredient, Indication, Developer) 2006
chapter eight: Market Summary
Table 8-1: World Market for Pain Management Drugs and Devices 2004-2010
Figure 8-1: Total World Pain Management Market 2004-2010
Table 8-2: Total World Pain Management Market by Pain Type 2006 vs 2010
Figure 8-2: The World Pain Management Market Share by Pain Type 2006
Figure 8-3: The World Pain Management Market Share by Pain Type 2010
Table 8-3: Revenues and Market Share by Top 16 Revenue-ProducingDrugs 2006
Figure 8-4: Market Share by Top Revenue Producing Drug 2006
Table 8-4: World Market for Top Pain Management Treatments Revenues and Segments of Participation by Major Areas of Participation 2006
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