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3-(2-Aminoethyl)pyridine analogs as alpha4beta2 nicotinic cholinergic receptor ligands.

Bioorganic & medicinal chemistry letters 2005 Oct 1; 15(19):4308-12

Link to PubMed abstract

Dukat M M, Ramunno A A, Banzi R R, Damaj M MI, Martin B B, Glennon R RA

Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298-0540, USA.

An examination of several 3-(2-aminoethyl)pyridine analogs suggests that they likely orient at alpha4beta2 nicotinic cholinergic receptors in a different fashion than their correspondingly substituted nicotine analogs.