DailyUpdates for Breaking Research
DailyUpdates features breaking research judged by LeadDiscovery's editorial team to be of key importance to drug development. Papers are selected from over 10,000 published each week from most pear reviewed journals.
A list of headline articles featured over the past week are listed below.
To submit you paper to be listed on DailyUpdates contact LeadDiscovery.
Research featured over the past 5 days
- Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.
- Does 3-day course of oral amoxycillin benefit children of non-severe pneumonia with wheeze: a multicentric randomised controlled trial.
- SILDENAFIL MEDIATED NEOVASCULARIZATION AND PROTECTION AGAINST MYOCARDIAL ISCHEMIA REPERFUSION INJURY IN RATS: PROBABLE ROLE OF VEGF/ ANGIOPOIETIN-1.
- Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B.
- Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates.
- Immunomodulatory drugs Revlimid((R)) (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation.
- Interrelations between diabetes therapy, self-monitoring of blood glucose, blood glucose and non-fatal or fatal endpoints in patients with type 2 diabetes / results of a longitudinal cohort study (ROSSO 5).
- Combining the Antigen Processing Components TAP and Tapasin Elicits Enhanced Tumor-Free Survival.
- High cholesterol levels are associated with reduced prostate cancer mortality rates during periods of high but not low statin use in the United States.
- A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling.
- First administration of cytidine diphosphocholine and galantamine in schizophrenia: a sustained alpha7 nicotinic agonist strategy.
- Differential block of sensory neuronal voltage-gated sodium channels by lacosamide, lidocaine and carbamazepine.
- Fragment Based Design of New H4 Receptor-Ligands with Anti-inflammatory Properties in Vivo.
- Isoxazolone Based Inhibitors of p38 MAP Kinases.
- Hepatic uptake and excretion of YM758, a novel If channel inhibitor, in rats and humans.
- Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles.
- Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats.
- A randomized, double-blind, phase IIa dose-finding study of Vandetanib (ZD6474) in Japanese patients with non-small cell lung cancer.
- Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancer in vivo.
- Comparison of a novel HPV test with the Hybrid Capture II (hcII) and a reference PCR method shows high specificity and positive predictive value for 13 high-risk human papillomavirus infections.