DailyUpdates for Breaking Research
DailyUpdates features breaking research judged by LeadDiscovery's editorial team to be of key importance to drug development. Papers are selected from over 10,000 published each week from most pear reviewed journals.
A list of headline articles featured over the past week are listed below.
To submit you paper to be listed on DailyUpdates contact LeadDiscovery.
Research featured over the past 5 days
- Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis.
- Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis.
- Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis.
- Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis.
- Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.
- Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs.
- Estrogen Receptor-α Variant, ER-α36, is Involved in Tamoxifen Resistance and Estrogen Hypersensitivity.
- Transgenic mice overexpressing CD109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing.
- Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1.
- Pharmacokinetic profile of liposome bupivacaine injection following a single administration at the surgical site.
- Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals.
- CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated.
- Decrease of PDSS2 expression, a novel tumor suppressor, in non-small cell lung cancer.
- Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
- A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.
- CD24 is an effector of HIF-1 driven primary tumor growth and metastasis.
- Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion.
- Use of low-dose combined therapy with gemcitabine and paclitaxel for advanced urothelial cancer patients with resistance to cisplatin-containing therapy: a retrospective analysis.
- Extended pain relief trial utilizing infiltration of Exparel(®), a long-acting multivesicular liposome formulation of bupivacaine: a Phase IV health economic trial in adult patients undergoing open colectomy.
- Differential effects of infliximab on absolute circulating blood leucocyte counts of innate immune cells in early and late rheumatoid arthritis patients.