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Cardiovascular disorders



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Today's headline articles

Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.

Today's journal articles

Effect of a New Class of Compounds of the Group of Substituted 5r1, 6h2-1,3,4-Thiadiazine-2-Amines on the Inflammatory and Cytokine Response in Experimental Myocardial Infarction.

PPARδ Agonist GW501516 Inhibits PDGF-Stimulated Pulmonary Arterial Smooth Muscle Cell Function Related to Pathological Vascular Remodeling.

Potentiated therapeutic angiogenesis by primed human mesenchymal stem cells in a mouse model of hindlimb ischemia.

Do you need further information on any of the agents being evaluated in the trial(s) below?  Let us know...

New Clinical Trials

AVJ-301 Clinical Trial: A Clinical Evaluation of AVJ-301 (Absorbâ„¢ BVS) in Japanese Population

A Phase 1 Study to Assess the Safety,Tolerability, and Pharmacokinetics of GS-6615 in Healthy Subjects

Previous Journal Entries

Intracoronary Adenosine versus Intravenous Adenosine during Primary PCI for ST-Elevation Myocardial Infarction: Which One Offers Better Outcomes in terms of Microvascular Obstruction?

Role of adenosine A2A receptor in organ-specific vascular reactivity following hemorrhagic shock in rats.

Role of Interferon Regulatory Factor 4 in the Regulation of Pathological Cardiac Hypertrophy.

A Highly Reproducible Model of Cerebral Ischemia/Reperfusion with Extended Survival in CB-17 Mice.

Reperfusion of cerebral artery thrombosis by the GPIb/vWF blockade with the nanobody ALX-0081 reduces brain infarct size in guinea pigs.

Inhibitory effects of p38 inhibitor against mitochondrial dysfunction in the early brain injury after subarachnoid hemorrhage in mice.

Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.

Apelin and APJ, a novel critical factor and therapeutic target for atherosclerosis.

Discovery of Rho-kinase inhibitors by docking-based virtual screening.

MicroRNA-21 and -146b are involved in the pathogenesis of murine viral myocarditis by regulating TH-17 differentiation.

A pilot study of the effect of spironolactone therapy on exercise capacity and endothelial dysfunction in pulmonary arterial hypertension: study protocol for a randomized controlled trial.

Increase ICAM-1 and LFA-1 expression by cerebrospinal fluid of subarachnoid hemorrhage patients: Involvement of TNF-α

Effect of New Method of Intracoronary Adenosine Injection during Primary Percutaneous Coronary Intervention on Microvascular Reperfusion Injury - Clinical Outcome and 1-Year Follow-Up.

Lifetime cost-effectiveness analysis of ticagrelor in patients with acute coronary syndromes based on the PLATO trial: a Singapore healthcare perspective.

The Role of Depression in Medication Adherence Among Heart Failure Patients.

Roles of Histone Deacetylation and AMP Kinase in Regulation of Cardiomyocyte PGC-1α Gene Expression in Hypoxia.

Etanercept Improves Lipid Profile and Oxidative Stress Measures in Patients with Juvenile Idiopathic Arthritis.

Epidermal growth factor receptor inhibitor PKI-166 governs cardiovascular protection without beneficial effects on the kidney in hypertensive 5/6 nephrectomised rats.

Current practice of antiarrhythmic drug therapy for prevention of atrial fibrillation in Europe: The European Heart Rhythm Association survey.

Aptamer BAX 499 Mediates Inhibition of Tissue Factor Pathway Inhibitor Via Interaction with Multiple Domains of the Protein.

Today's News Items

Bayer Submits Investigational Drug Riociguat for Patients with Chronic Thromboembolic Pulmonary Hypertension for Regulatory Approval in Japan

Training Courses & Meetings

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Previous News Items

SORIN GROUP ANNOUNCES FDA APPROVAL AND U.S. LAUNCH OF SMARTVIEW (tm) REMOTE MONITORING SOLUTION FOR PATIENTS WITH IMPLANTED CARDIAC DEFIBRILLATORS

FDA Accepts Biogen Idec’s Biologics License Application for First Long-Lasting Factor VIII Therapy for Hemophilia A