Today's journal articles

Efficacy And Safety Of Lixisenatide Once Daily Versus Placebo In Type 2 Diabetes Insufficiently Controlled On Pioglitazone (Getgoal-P).

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New Clinical Trials

A Study in CKD Patients With Type 2 Diabetes Mellitus and Albuminuria

Previous Journal Entries

Omentin-1 Stimulates Human Osteoblast Proliferation through PI3K/Akt Signal Pathway.

Evaluating Second-Line Treatment Options for Type 2 Diabetes: Focus on Secondary Effects of GLP-1 Agonists and DPP-4 Inhibitors.

Blockage of Peripheral NPY Y1 and Y2 Receptors Modulates Barorefex Sensitivity of Diabetic Rats.

Efficacy and safety over 26 weeks of an oral treatment strategy including sitagliptin compared with an injectable treatment strategy with liraglutide in patients with type 2 diabetes mellitus inadequately controlled on metformin: a randomised clinical trial.

Therapeutic Effect of MG132 on the Aortic Oxidative Damage and Inflammatory Response in OVE26 Type 1 Diabetic Mice.

PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway.

Towards a humanized PPARγ reporter system for in vivo screening of obesogens.

N-glycosylation modulates the membrane sub-domain distribution and activity of glucose transporter 2 in pancreatic beta cells.

Apelin and APJ, a novel critical factor and therapeutic target for atherosclerosis.

Blockade of substance P receptor attenuates osteoporotic pain, but not bone loss, in ovariectomized mice.

A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice.

Renoprotective Effect of Pioglitazone by the Prevention of Glomerular Hyperfiltration through the Possible Restoration of Altered Macula Densa Signaling in Rats with Type 2 Diabetic Nephropathy.

Two Novel Vitamin D Receptor Modulators with Similar Structures Exhibit Different Hypercalcemic Effects in 5/6 Nephrectomized Uremic Rats.

Poly-ADP-Ribose-Polymerase Inhibition Ameliorates Hind Limb Ischemia Reperfusion Injury in a Murine Model of Type 2 Diabetes.

Orally efficacious novel small molecule 6Cl-TGQ stimulates insulin receptor and alleviates diabetes.

PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during Type 1 Diabetes.

ABLATION OF DIHYDROCERAMIDE DESATURASE-1, A THERAPEUTIC TARGET FOR THE TREATMENT OF METABOLIC DISEASES, SIMULTANEOUSLY STIMULATES ANABOLIC AND CATABOLIC SIGNALING.

Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function and Glucose Metabolism in Non-Diabetic Subjects.

A unique small molecule inhibitor of enolase clarifies its role in fundamental biological processes.

Design and synthesis of 2 - substituted benzoxazoles as novel PTP1B inhibitors.

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Piramal Enterprises Limited receives IND approval from the US FDA for its GPR40 agonist P11187; an anti-diabetic molecule

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