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Metabolic & Hormonal disorders



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Today's journal articles

Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells.

Do you need further information on any of the agents being evaluated in the trial(s) below?  Let us know...

New Clinical Trials

Safety and Efficacy of Exenatide Once Weekly Versus Liraglutide in Subjects With Type 2 Diabetes

A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1)in Type 2 Diabetes Mellitus

Previous Journal Entries

Direct medical cost of overweight and obesity in the USA: a quantitative systematic review.

Ritonavir protects against the development of atherosclerosis in APOE*3-Leiden mice.

Cost-effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in newly diagnosed type 2 diabetes in Germany.

Effect of month-long treatment with oral N-acetylcysteine on the oxidative stress and proteinuria in patients with diabetic nephropathy: a pilot study.

Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist.

Effectiveness of the Early Addition of Rosiglitazone to Control Hyperglycemia After Unsuccessful Submaximal Sulphonylurea Monotherapy: The Rosiglitazone Early Versus SULphonylurea Titration (RESULT) Study.

Fructose - 1,6 - bisphosphatase Inhibitors. 2. Design, synthesis, and structure - activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5' - adenosinemonophosphate (AMP) mimics.

A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model.

Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice.

The Effect of Colesevelam Hydrochloride on Insulin Sensitivity and Secretion in Patients With Type 2 Diabetes: A Pilot Study.

Gene Transfer of TRPC6(DN) (Dominant Negative) Restores Erectile Function in Diabetic Rats.

Novel bis - arylsulfonamides and aryl sulfonimides as inactivators of plasminogen activator inhibitor - 1 (PAI - 1).

Design, synthesis and in vitro characterization of Glucagon - Like Peptide - 1 derivatives for pancreatic beta cell imaging by SPECT.

A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats.

Effects of Exenatide on Systolic Blood Pressure in Subjects With Type 2 Diabetes.

Colestilan monotherapy significantly improves glycaemic control and LDL cholesterol levels in patients with type 2 diabetes: a randomized double-blind placebo-controlled study.

Critical role of arcuate Y4 receptors and the melanocortin system in pancreatic polypeptide-induced reduction in food intake in mice.

The SLIM Study: Slo-Niacin(R) and Atorvastatin Treatment of Lipoproteins and Inflammatory Markers in Combined Hyperlipidemia.

Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1.

Discovery of cyclicsulfonamide derivatives as 11beta - hydroxysteroid dehydrogenase 1 inhibitors.

Today's News Items

Recruitment Completed for ASSERT

Training Courses & Meetings

No events listed

Previous News Items

PROLOR BIOTECH REPORTS POSITIVE TOP-LINE RESULTS FROM PHASE I STUDY OF ITS LONGER-ACTING VERSION OF HUMAN GROWTH HORMONE

Repros\' New IND for the Investigation of AndroxalŽ in the Treatment of Type II Diabetes in Men with Secondary Hypogonadism is Now Effective