Today's headline articles

Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.

Today's journal articles

Combinational effect of PPARγ agonist and RXR agonist on the growth of SGC7901 gastric carcinoma cells in vitro.

Oxaliplatin Plus 5-Fluorouracil and Folinic Acid (OFF) in Gemcitabine-Pretreated Advanced Pancreatic Cancer: A Phase II Study.

Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-κB signaling pathway with distinct mechanisms.

Axitinib and/or bevacizumab with modified FOLFOX-6 as first-line therapy for metastatic colorectal cancer: A randomized phase 2 study.

A randomized phase II non-comparative study of pemetrexed‑carboplatin and gemcitabine‑vinorelbine in anthracycline- and taxane-pretreated advanced breast cancer patients.

Cognitive Complaints After Breast Cancer Treatments: Examining the Relationship With Neuropsychological Test Performance.

MiR - 125b regulates side population in breast cancer and confers a chemoresistant phenotype.

Multimodal imaging of tumor response to sorafenib combined with radiation therapy: comparison between diffusion-weighted MRI, choline spectroscopy and (18) F-FLT PET imaging.

Do you need further information on any of the agents being evaluated in the trial(s) below?  Let us know...

New Clinical Trials

A Multicenter, Open-label, Dose-finding Trial of OPC-41061 to Investigate Efficacy, Pharmacokinetics, Pharmacodynamics, and Safety in Patients With Carcinomatous Edema (Phase 2)

A Phase II Study of Dovitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands

Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer

Previous Journal Entries

MiR-150 Blocks MLL-AF9 Associated Leukemia By Repressing Multiple Oncogenes.

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias.

microRNA-125a-3p reduces cells proliferation and migration by targeting Fyn.

Total Synthesis of Potent Antitumor Macrolide, ( - ) - Zampanolide: An Oxidative Intramolecular Cyclization - Based Strategy.

Upregulation of microRNA-155 promotes the migration and invasion of colorectal cancer cells through the regulation of claudin-1 expression.

Proteomic and cytokine plasma biomarkers for predicting progression from colorectal adenoma to carcinoma in human patients.

Evaluation of the novel USPIO GEH121333 for MR imaging of cancer immune responses.

Role of mTOR Inhibition in Preventing Resistance and Restoring Sensitivity to Hormone-Targeted and HER2-Targeted Therapies in Breast Cancer.

Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo.

Anti-cancer effect of a quinoxaline derivative GK13 as a transglutaminase 2 inhibitor.

Anti-Cancer Effect of HS-345, a New Tropomyosin-Related Kinase A Inhibitor, on Human Pancreatic Cancer.

Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma.

Imaging and therapy of hSSTR2-transfected tumors using radiolabeled somatostatin analogs.

Antibody-Functionalized Magnetic Polymersomes: In vivo Targeting and Imaging of Bone Metastases using High Resolution MRI.

Nkx2-8 Downregulation Promotes Angiogenesis and Activates NF-κB in Esophageal Cancer.

Indole-3-carbinol inhibits cell proliferation and induces apoptosis in Hep-2 laryngeal cancer cells.

Risk of osteonecrosis of the jaw in cancer patients receiving denosumab: a meta-analysis of seven randomized controlled trials.

Phase 1 Dose-Escalation Study of VB-111, an Anti-Angiogenic Virotherapy, in Patients with Advanced Solid Tumors.

A novel platinum complex of the histone deacetylase inhibitor belinostat: Rational design, development and in vitro cytotoxicity.

Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs.

Today's News Items

Sanofi Reports Positive Topline Results from Pivotal Phase III JAKARTA Study for JAK2 Inhibitor in Myelofibrosis

New Analyses Identify Predictive Biomarkers For Vectibix® (Panitumumab) In Patients With Metastatic Colorectal Cancer

Training Courses & Meetings

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Previous News Items

Seattle Genetics Announces ADCETRIS® (Brentuximab Vedotin) Supplemental BLA Accepted for Filing by the FDA

FDA approves Tarceva (erlotinib) tablets and cobas EGFR Mutation Test for specific type of lung cancer

Bayer Receives U.S. FDA Approval for Cancer Treatment Xofigo® (radium 223 dichloride) Injection

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